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Protein
Submitted name:

MutL protein homolog 1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
MutL protein homolog 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiQ59EG3
PRIDEiQ59EG3

Structurei

3D structure databases

ProteinModelPortaliQ59EG3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 200DNA_mis_repairInterPro annotationAdd BLAST120

Phylogenomic databases

eggNOGiKOG1979 Eukaryota
COG0323 LUCA
HOGENOMiHOG000176000
HOVERGENiHBG006374

Family and domain databases

Gene3Di3.30.230.10, 1 hit
3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR011186 DNA_mismatch_repair_MLH1
IPR013507 DNA_mismatch_S5_2-like
IPR036890 HATPase_C_sf
IPR032189 Mlh1_C
IPR038973 MutL/Mlh/Pms
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
PANTHERiPTHR10073 PTHR10073, 2 hits
PTHR10073:SF40 PTHR10073:SF40, 2 hits
PfamiView protein in Pfam
PF01119 DNA_mis_repair, 1 hit
PF16413 Mlh1_C, 2 hits
SMARTiView protein in SMART
SM01340 DNA_mis_repair, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit

Sequencei

Sequence statusi: Fragment.

Q59EG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KPLLNHVLAI KGPRSRWRTF FYNIATRRKA LKNPSEEYGK ILEVVGRYSV
60 70 80 90 100
HNAGISFSVK KQGETVADVR TLPNASTVDN IRSIFGNAVS RELIEIGCED
110 120 130 140 150
KTLAFKMNGY ISNANYSVKK CIFLLFINHR LVESTSLRKA IETVYAAYLP
160 170 180 190 200
KNTHPFLYLS LEISPQNVDV NVHPTKHEVH FLHEESILER VQQHIESKLL
210 220 230 240 250
GSNSSRMYFT QTLLPGLAGP SGEMVKSTTS LTSSSTSGSS DKVYAHQMVR
260 270 280 290 300
TDSREQKLDA FLQPLSKPLS SQPQAIVTED KTDISSGRAR QQDEEMLELP
310 320 330 340 350
APAEVAAKNQ SLEGDTTKGT SEMSEKRGPT SSNPRKRHRE DSDVEMVEDD
360 370 380 390 400
SRKEMTAACT PRRRIINLTS VLSLQEEINE QGHEVLREML HNHSFVGCVN
410 420 430 440 450
PQWALAQHQT KLYLLNTTKL SEELFYQILI YDFANFGVLR LSEPAPLFDL
460 470 480 490 500
AMLALDSPES GWTEEDGPKE GLAEYIVEFL KKKAEMLADY FSLEIDESEV
510 520 530 540 550
PGSIPNSWKW TVEHIVYKAL RSHILPPKHF TEDGNILQLA NLPDLYKVFE

RC
Length:552
Mass (Da):62,370
Last modified:April 26, 2005 - v1
Checksum:i01E87FCC54DBF6F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209848 mRNA Translation: BAD93085.1
RefSeqiNP_001245200.1, NM_001258271.1
UniGeneiHs.195364

Genome annotation databases

GeneIDi4292

Similar proteinsi

Entry informationi

Entry nameiQ59EG3_HUMAN
AccessioniPrimary (citable) accession number: Q59EG3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 20, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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