Q59EG0 (Q59EG0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Basement membrane-specific heparan sulfate proteoglycan core protein variant EMBL BAD93088.1
Organism	Homo sapiens (Human) EMBL BAD93088.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	2331 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat SAAS SAAS001791
PTM	Disulfide bond SAAS SAAS001791
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD93088.1

Sequences

	Sequence		Length	Mass (Da)
	Q59EG0 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: ABACA99726A7A34C	FASTA	2,331	246,413
	10 20 30 40 50 60 SVTEGQTLDL NCVVAGSAHA QVTWYRRGGS LPPHTQVHGS RLRLPQVSPA DSGEYVCRVE 70 80 90 100 110 120 NGSGPKEASI TVSVLHGTHS GPSYTPVPGS TRPIRIEPSS SHVAEGQTLD LNCVVPGQAH 130 140 150 160 170 180 AQVTWHKRGG SLPARHQTHG SLLRLHQVTP ADSGEYVCHV VGTSGPLEAS VLVTIEASVI 190 200 210 220 230 240 PGPIPPVRIE SSSSTVAEGQ TLDLSCVVAG QAHAQVTWYK RGGSLPARHQ VRGSRLYIFQ 250 260 270 280 290 300 ASPADAGQYV CRASNGMEAS ITVTVTGTQG ANLAYPAGST QPIRIEPSSS QVAEGQTLDL 310 320 330 340 350 360 NCVVPGQSHA QVTWHKRGGS LPVRHQTHGS LLRLYQASPA DSGEYVCRVL GSSVPLEASV 370 380 390 400 410 420 LVTIEPAGSV PALGVTPTVR IESSSSQVAE GQTLDLNCLV AGQAHAQVTW HKRGGSLPAR 430 440 450 460 470 480 HQVHGSRLRL LQVTPADSGE YVCRVVGSSG TQEASVLVTI QQRLSGSHSQ GVAYPVRIES 490 500 510 520 530 540 SSASLANGHT LDLNCLVASQ APHTITWYKR GGSLPSRHQI VGSRLRIPQV TPADSGEYVC 550 560 570 580 590 600 HVSNGAGSRE TSLIVTIQGS GSSHVPSVSP PIRIESSSPT VVEGQTLDLN CVVARQPQAI 610 620 630 640 650 660 ITWYKRGGSL PSRHQTHGSH LRLHQMSVAD SGEYVCRANN NIDALEASIV ISVSPSAGSP 670 680 690 700 710 720 SAPGSSMPIR IESSSSHVAE GETLDLNCVV PGQAHAQVTW HKRGGSLPSH HQTRGSRLRL 730 740 750 760 770 780 HHVSPADSGE YVCRVMGSSG PLEASVLVTI EASGSSAVHV PAPGGAPPIR IEPSSSRVAE 790 800 810 820 830 840 GQTLDLKCVV PGQAHAQVTW HKRGGNLPAR HQVHGPLLRL NQVSPADSGE YSCQVTGSSG 850 860 870 880 890 900 TLEASVLVTI EPSSPGPIPA PGLAQPIYIE ASSSHVTEGQ TLDLNCVVPG QAHAQVTWYK 910 920 930 940 950 960 RGGSLPARHQ THGSQLRLHL VSPADSGEYV CRAASGPGPE QEASFTVTVP PSEGSSYRLR 970 980 990 1000 1010 1020 SPVISIDPPS STVQQGQDAS FKCLIHDGAA PISLEWKTRN QELEDNVHIS PNGSIITIVG 1030 1040 1050 1060 1070 1080 TRPSNHGTYR CVASNAYGVA QSVVNLSVHG PPTVSVLPEG PVWVKVGKAV TLECVSAGEP 1090 1100 1110 1120 1130 1140 RSSARWTRIS STPAKLEQRT YGLMDSHAVL QISSAKPSDA GTYVCLAQNA LGTAQKQVEV 1150 1160 1170 1180 1190 1200 IVDTGAMAPG APQVQAEEAE LTVEAGHTAT LRCSATGSPA PTIHWSKLRS PLPWQYRLEG 1210 1220 1230 1240 1250 1260 DTLIIPRVAQ QDSGQYICNA TSPAGHAEAT IILHVESPPY ATTVPEHASV QAGETVQLQC 1270 1280 1290 1300 1310 1320 LAHGTPPLTF QWSRVGSSLP GRATARNELL HFERAAPEDS GRYRCRVTNK VGSAEAFAQL 1330 1340 1350 1360 1370 1380 LVQGPPGSLP ATSIPAGSTP TVQVTPQLET KSIGASVEFH CAVPSDRGTQ LRWFKEGGQL 1390 1400 1410 1420 1430 1440 PPGHSVQDGV LRIQNLDQSC QGTYICQAHG PWGKAQASAQ LVIQALPSVL INIRTSVQTV 1450 1460 1470 1480 1490 1500 VVGHAVEFEC LALGDPKPQV TWSKVGGHLR PGIVQSGGVV RIAHVELADA GQYRCTATNA 1510 1520 1530 1540 1550 1560 AGTTQSHVLL LVQALPQISM PQEVRVPAGS AAVFPCIASG YPTPDISWSK LDGSLPPDSR 1570 1580 1590 1600 1610 1620 LENNMLMLPS VRPQDAGTYV CTATNRQGKV KAFAHLQVPE RVVPYFTQTP YSFLPLPTIK 1630 1640 1650 1660 1670 1680 DAYRKFEIKI TFRPDSADGM LLYNGQKRVP GSPTNLANRQ PDFISFGLVG GRPEFRFDAG 1690 1700 1710 1720 1730 1740 SGMATIRHPT PLALGHFHTV TLLRSLTQGS LIVGDLAPVN GTSQGKFQGL DLNEELYLGG 1750 1760 1770 1780 1790 1800 YPDYGAIPKA GLSSGFIGCV RELRIQGEEI VFHDLNLTAH GISHCPTCRD RPCQNGGQCH 1810 1820 1830 1840 1850 1860 DSESSSYVCV CPAGFTGSRC EHSQALHCHP EACGPDATCV NRPDGRGYTC RCHLGRSGLR 1870 1880 1890 1900 1910 1920 CEEGVTVTTP SLSGAGSYLA LPALTNTHHE LRLDVEFKPL APDGVLLFSG GKSGPVEDFV 1930 1940 1950 1960 1970 1980 SLAMVGGHLE FRYELGSGLA VLRSAEPLAL GRWHRVSAER LNKDGSLRVN GGRPVLRSSP 1990 2000 2010 2020 2030 2040 GKSQGLNLHT LLYLGGVEPS VPLSPATNMS AHFRGCVGEV SVNGKRLDLT YSFLGSQGIG 2050 2060 2070 2080 2090 2100 QCYDSSPCER QPCQHGATCM PAGEYEFQCL CRDGFKGDLC EHEENPCQLR EPCLHGGTCQ 2110 2120 2130 2140 2150 2160 GTRCLCLPGF SGPRCQQGSG HGIAESDWHL EGSGGNDAPG QYGAYFHDDG FLAFPGHVFS 2170 2180 2190 2200 2210 2220 RSLPEVPETI ELEVRTSTAS GLLLWQGVEV GEAGQGKDFI SLGLQDGHLV FRYQLGSGEA 2230 2240 2250 2260 2270 2280 RLVSEDPIND GEWHRVTALR EGRRGSIQVD GEELVSGRSP GPNVAVNAKG NVYIGGAPDV 2290 2300 2310 2320 2330 ATLTGGRFSS GITGCVKNLV LHSARPGAPP PQPLDLQHRA QAGANTRPCP S

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Aorta endothelial cell EMBL BAD93088.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209851 mRNA. Translation: BAD93088.1.
IPI	IPI00024284.
UniGene	Hs.562227.
3D structure databases
ProteinModelPortal	Q59EG0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59EG0.
Proteomic databases
PRIDE	Q59EG0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000049276.
HOVERGEN	HBG008174.
Gene expression databases
ArrayExpress	Q59EG0.
Family and domain databases
Gene3D	2.60.120.200. 3 hits. 2.60.40.10. 17 hits.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR000742. EG-like_dom. IPR013032. EGF-like_CS. IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR013098. Ig_I-set. IPR003598. Ig_sub2. IPR001791. Laminin_G. [Graphical view]
Pfam	PF00008. EGF. 1 hit. PF12661. hEGF. 2 hits. PF07679. I-set. 15 hits. PF00054. Laminin_G_1. 2 hits. PF02210. Laminin_G_2. 1 hit. [Graphical view]
SMART	SM00181. EGF. 4 hits. SM00408. IGc2. 17 hits. SM00282. LamG. 3 hits. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 3 hits.
PROSITE	PS00022. EGF_1. 4 hits. PS01186. EGF_2. 3 hits. PS50026. EGF_3. 4 hits. PS50835. IG_LIKE. 17 hits. PS50025. LAM_G_DOMAIN. 3 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q59EG0_HUMAN

Accession

Primary (citable) accession number: Q59EG0

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	March 6, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.