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Q59ED7

- Q59ED7_HUMAN

UniProt

Q59ED7 - Q59ED7_HUMAN

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Protein
Submitted name: Putative uncharacterized protein
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. FMN binding Source: Ensembl
  2. NADP binding Source: Ensembl
  3. NADPH-hemoprotein reductase activity Source: UniProtKB-EC
  4. cytochrome-b5 reductase activity, acting on NAD(P)H Source: Ensembl
  5. electron carrier activity Source: Ensembl
  6. flavin adenine dinucleotide binding Source: Ensembl
  7. hydrolase activity Source: Ensembl
  8. iron ion binding Source: InterPro
  9. iron-cytochrome-c reductase activity Source: Ensembl
  10. nitric oxide dioxygenase activity Source: Ensembl

GO - Biological processi

  1. carnitine metabolic process Source: Ensembl
  2. cellular response to follicle-stimulating hormone stimulus Source: Ensembl
  3. cellular response to peptide hormone stimulus Source: Ensembl
  4. demethylation Source: Ensembl
  5. fatty acid oxidation Source: Ensembl
  6. flavonoid metabolic process Source: Ensembl
  7. internal peptidyl-lysine acetylation Source: Ensembl
  8. negative regulation of apoptotic process Source: Ensembl
  9. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
  10. negative regulation of lipase activity Source: Ensembl
  11. nitrate catabolic process Source: Ensembl
  12. nitric oxide catabolic process Source: Ensembl
  13. positive regulation of cholesterol biosynthetic process Source: Ensembl
  14. positive regulation of chondrocyte differentiation Source: Ensembl
  15. positive regulation of smoothened signaling pathway Source: Ensembl
  16. positive regulation of steroid hormone biosynthetic process Source: Ensembl
  17. regulation of growth plate cartilage chondrocyte proliferation Source: Ensembl
  18. response to drug Source: Ensembl
  19. response to nutrient Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  2. mitochondrion Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ59ED7.

Expressioni

Gene expression databases

ArrayExpressiQ59ED7.
BgeeiQ59ED7.

Structurei

3D structure databases

ProteinModelPortaliQ59ED7.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000282027.
HOVERGENiHBG000432.

Family and domain databases

Gene3Di1.20.990.10. 1 hit.
3.40.50.360. 1 hit.
InterProiIPR003097. FAD-binding_1.
IPR017927. Fd_Rdtase_FAD-bd.
IPR001094. Flavdoxin.
IPR008254. Flavodoxin/NO_synth.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR029039. Flavoprotein-like.
IPR023173. NADPH_Cyt_P450_Rdtase_dom3.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR023208. P450R.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PfamiPF00667. FAD_binding_1. 1 hit.
PF00258. Flavodoxin_1. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000208. P450R. 1 hit.
PRINTSiPR00369. FLAVODOXIN.
PR00371. FPNCR.
SUPFAMiSSF52218. SSF52218. 1 hit.
SSF63380. SSF63380. 1 hit.
PROSITEiPS51384. FAD_FR. 1 hit.
PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59ED7-1 [UniParc]FASTAAdd to Basket

« Hide

PGCQRFMINM GDSHVDTSST VSEAVAEEVS LFSMTDMILF SLIVGLLTYW    50
FLFRKKKEEV PEFTKIQTLT SSVRESSFVE KMKKTGRNII VFYGSQTGTA 100
EEFANRLSKD AHRYGMRGMS ADPEEYDLAD LSSLPEIDNA LVVFCMATYG 150
EGDPTDNAQD FYDWLQETDV DLSGVKFAVF GLGNKTYEHF NAMGKYVDKR 200
LEQLGAQRIF ELGLGDDDGN LEEDFITWRE QFWPAVCEHF GVEATGEESS 250
IRQYELVVHT DIDAAKVYMG EMGRLKSYEN QKPPFDAKNP FLAAVTTNRK 300
LNQGTERHLM HLELDISDSK IRYESGDHVA VYPANDSALV NQLGKILGAD 350
LDVVMSLNNL DEESNKKHPF PCPTSYRTAL TYYLDITNPP RTNVLYELAQ 400
YASEPSEQEL LRKMASSSGE GKELYLSWVV EARRHILAIL QDCPSLRPPI 450
DHLCELLPRL QARYYSIASS SKVHPNSVHI CAVVVEYETK AGRINKGVAT 500
NWLRAKEPAG ENGGRALVPM FVRKSQFRLP FKATTPVIMV GPGTGVAPFI 550
GFIQERAWLR QQGKEVGETL LYYGCRRSDE DYLYREELAQ FHRDGALTQL 600
NVAFSREQSH KVYVQHLLKQ DREHLWKLIE GGAHIYVCGD ARNMARDVQN 650
TFYDIVAELG AMEHAQAVDY IKKLMTKGRY SLDVWS 686
Length:686
Mass (Da):77,737
Last modified:April 26, 2005 - v1
Checksum:i453DAD59A3F48655
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209874 mRNA. Translation: BAD93111.1.
UniGeneiHs.354056.

Genome annotation databases

UCSCiuc003udy.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209874 mRNA. Translation: BAD93111.1 .
UniGenei Hs.354056.

3D structure databases

ProteinModelPortali Q59ED7.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q59ED7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc003udy.3. human.

Phylogenomic databases

HOGENOMi HOG000282027.
HOVERGENi HBG000432.

Gene expression databases

ArrayExpressi Q59ED7.
Bgeei Q59ED7.

Family and domain databases

Gene3Di 1.20.990.10. 1 hit.
3.40.50.360. 1 hit.
InterProi IPR003097. FAD-binding_1.
IPR017927. Fd_Rdtase_FAD-bd.
IPR001094. Flavdoxin.
IPR008254. Flavodoxin/NO_synth.
IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
IPR029039. Flavoprotein-like.
IPR023173. NADPH_Cyt_P450_Rdtase_dom3.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR023208. P450R.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view ]
Pfami PF00667. FAD_binding_1. 1 hit.
PF00258. Flavodoxin_1. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF000208. P450R. 1 hit.
PRINTSi PR00369. FLAVODOXIN.
PR00371. FPNCR.
SUPFAMi SSF52218. SSF52218. 1 hit.
SSF63380. SSF63380. 1 hit.
PROSITEi PS51384. FAD_FR. 1 hit.
PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Aorta endothelial cellImported.

Entry informationi

Entry nameiQ59ED7_HUMAN
AccessioniPrimary (citable) accession number: Q59ED7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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