Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q59ED7

- Q59ED7_HUMAN

UniProt

Q59ED7 - Q59ED7_HUMAN

Protein
Submitted name:

Putative uncharacterized protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. cytochrome-b5 reductase activity, acting on NAD(P)H Source: Ensembl
    2. electron carrier activity Source: Ensembl
    3. flavin adenine dinucleotide binding Source: Ensembl
    4. FMN binding Source: Ensembl
    5. hydrolase activity Source: Ensembl
    6. iron-cytochrome-c reductase activity Source: Ensembl
    7. iron ion binding Source: InterPro
    8. NADP binding Source: Ensembl
    9. NADPH-hemoprotein reductase activity Source: Ensembl
    10. nitric oxide dioxygenase activity Source: Ensembl

    GO - Biological processi

    1. carnitine metabolic process Source: Ensembl
    2. cellular response to follicle-stimulating hormone stimulus Source: Ensembl
    3. cellular response to peptide hormone stimulus Source: Ensembl
    4. demethylation Source: Ensembl
    5. fatty acid oxidation Source: Ensembl
    6. flavonoid metabolic process Source: Ensembl
    7. internal peptidyl-lysine acetylation Source: Ensembl
    8. negative regulation of apoptotic process Source: Ensembl
    9. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
    10. negative regulation of lipase activity Source: Ensembl
    11. nitrate catabolic process Source: Ensembl
    12. nitric oxide catabolic process Source: Ensembl
    13. positive regulation of cholesterol biosynthetic process Source: Ensembl
    14. positive regulation of chondrocyte differentiation Source: Ensembl
    15. positive regulation of smoothened signaling pathway Source: Ensembl
    16. positive regulation of steroid hormone biosynthetic process Source: Ensembl
    17. regulation of growth plate cartilage chondrocyte proliferation Source: Ensembl
    18. response to drug Source: Ensembl
    19. response to nutrient Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: Ensembl
    2. mitochondrion Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ59ED7.

    Expressioni

    Gene expression databases

    ArrayExpressiQ59ED7.
    BgeeiQ59ED7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59ED7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000282027.
    HOVERGENiHBG000432.

    Family and domain databases

    Gene3Di1.20.990.10. 1 hit.
    3.40.50.360. 1 hit.
    InterProiIPR003097. FAD-binding_1.
    IPR017927. Fd_Rdtase_FAD-bd.
    IPR001094. Flavdoxin.
    IPR008254. Flavodoxin/NO_synth.
    IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
    IPR029039. Flavoprotein-like.
    IPR023173. NADPH_Cyt_P450_Rdtase_dom3.
    IPR001433. OxRdtase_FAD/NAD-bd.
    IPR023208. P450R.
    IPR017938. Riboflavin_synthase-like_b-brl.
    [Graphical view]
    PfamiPF00667. FAD_binding_1. 1 hit.
    PF00258. Flavodoxin_1. 1 hit.
    PF00175. NAD_binding_1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000208. P450R. 1 hit.
    PRINTSiPR00369. FLAVODOXIN.
    PR00371. FPNCR.
    SUPFAMiSSF52218. SSF52218. 1 hit.
    SSF63380. SSF63380. 1 hit.
    PROSITEiPS51384. FAD_FR. 1 hit.
    PS50902. FLAVODOXIN_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59ED7-1 [UniParc]FASTAAdd to Basket

    « Hide

    PGCQRFMINM GDSHVDTSST VSEAVAEEVS LFSMTDMILF SLIVGLLTYW    50
    FLFRKKKEEV PEFTKIQTLT SSVRESSFVE KMKKTGRNII VFYGSQTGTA 100
    EEFANRLSKD AHRYGMRGMS ADPEEYDLAD LSSLPEIDNA LVVFCMATYG 150
    EGDPTDNAQD FYDWLQETDV DLSGVKFAVF GLGNKTYEHF NAMGKYVDKR 200
    LEQLGAQRIF ELGLGDDDGN LEEDFITWRE QFWPAVCEHF GVEATGEESS 250
    IRQYELVVHT DIDAAKVYMG EMGRLKSYEN QKPPFDAKNP FLAAVTTNRK 300
    LNQGTERHLM HLELDISDSK IRYESGDHVA VYPANDSALV NQLGKILGAD 350
    LDVVMSLNNL DEESNKKHPF PCPTSYRTAL TYYLDITNPP RTNVLYELAQ 400
    YASEPSEQEL LRKMASSSGE GKELYLSWVV EARRHILAIL QDCPSLRPPI 450
    DHLCELLPRL QARYYSIASS SKVHPNSVHI CAVVVEYETK AGRINKGVAT 500
    NWLRAKEPAG ENGGRALVPM FVRKSQFRLP FKATTPVIMV GPGTGVAPFI 550
    GFIQERAWLR QQGKEVGETL LYYGCRRSDE DYLYREELAQ FHRDGALTQL 600
    NVAFSREQSH KVYVQHLLKQ DREHLWKLIE GGAHIYVCGD ARNMARDVQN 650
    TFYDIVAELG AMEHAQAVDY IKKLMTKGRY SLDVWS 686
    Length:686
    Mass (Da):77,737
    Last modified:April 26, 2005 - v1
    Checksum:i453DAD59A3F48655
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209874 mRNA. Translation: BAD93111.1.
    UniGeneiHs.354056.

    Genome annotation databases

    UCSCiuc003udy.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209874 mRNA. Translation: BAD93111.1 .
    UniGenei Hs.354056.

    3D structure databases

    ProteinModelPortali Q59ED7.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q59ED7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc003udy.3. human.

    Phylogenomic databases

    HOGENOMi HOG000282027.
    HOVERGENi HBG000432.

    Gene expression databases

    ArrayExpressi Q59ED7.
    Bgeei Q59ED7.

    Family and domain databases

    Gene3Di 1.20.990.10. 1 hit.
    3.40.50.360. 1 hit.
    InterProi IPR003097. FAD-binding_1.
    IPR017927. Fd_Rdtase_FAD-bd.
    IPR001094. Flavdoxin.
    IPR008254. Flavodoxin/NO_synth.
    IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase.
    IPR029039. Flavoprotein-like.
    IPR023173. NADPH_Cyt_P450_Rdtase_dom3.
    IPR001433. OxRdtase_FAD/NAD-bd.
    IPR023208. P450R.
    IPR017938. Riboflavin_synthase-like_b-brl.
    [Graphical view ]
    Pfami PF00667. FAD_binding_1. 1 hit.
    PF00258. Flavodoxin_1. 1 hit.
    PF00175. NAD_binding_1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000208. P450R. 1 hit.
    PRINTSi PR00369. FLAVODOXIN.
    PR00371. FPNCR.
    SUPFAMi SSF52218. SSF52218. 1 hit.
    SSF63380. SSF63380. 1 hit.
    PROSITEi PS51384. FAD_FR. 1 hit.
    PS50902. FLAVODOXIN_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Aorta endothelial cellImported.

    Entry informationi

    Entry nameiQ59ED7_HUMAN
    AccessioniPrimary (citable) accession number: Q59ED7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.