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Protein
Submitted name:

Phospholipase D1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Phospholipase D1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164742228.

PTM / Processingi

Proteomic databases

PaxDbiQ59EA4.
PRIDEiQ59EA4.

Expressioni

Gene expression databases

GenevisibleiQ59EA4. HS.

Structurei

3D structure databases

ProteinModelPortaliQ59EA4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 235PXInterPro annotationAdd BLAST132
Domaini482 – 509PLD phosphodiesteraseInterPro annotationAdd BLAST28
Domaini876 – 903PLD phosphodiesteraseInterPro annotationAdd BLAST28

Phylogenomic databases

eggNOGiKOG1329. Eukaryota.
COG1502. LUCA.
HOGENOMiHOG000246972.
HOVERGENiHBG006650.
KOiK01115.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.30.1520.10. 1 hit.
InterProiView protein in InterPro
IPR011993. PH-like_dom_sf.
IPR001849. PH_domain.
IPR001683. Phox.
IPR025202. PLD-like_dom.
IPR001736. PLipase_D/transphosphatidylase.
IPR016555. PLipase_D_euk.
IPR015679. PLipase_D_fam.
IPR036871. PX_dom_sf.
PANTHERiPTHR18896. PTHR18896. 2 hits.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
PF00614. PLDc. 1 hit.
PF13091. PLDc_2. 1 hit.
PF00787. PX. 1 hit.
PIRSFiPIRSF009376. Phospholipase_D_euk. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SM00155. PLDc. 2 hits.
SM00312. PX. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF64268. SSF64268. 1 hit.
PROSITEiView protein in PROSITE
PS50035. PLD. 2 hits.
PS50195. PX. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q59EA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ANAQVLAAPS PCSPFAFTLS KVNMSLKNEP RVNTSALQKI AADMSNIIEN
60 70 80 90 100
LDTRELHFEG EEVDYDVSPS DPKIQEVYIP FSAIYNTQGF KEPNIQTYLS
110 120 130 140 150
GCPIKAQVLE VERFTSTTRV PSINLYTIEL THGEFKWQVK RKFKHFQEFH
160 170 180 190 200
RELLKYKAFI RIPIPTRRHT FRRQNVREEP REMPSLPRSS ENMIREEQFL
210 220 230 240 250
GRRKQLEDYL TKILKMPMYR NYHATTEFLD ISQLSFIHDL GPKGIEGMIM
260 270 280 290 300
KRSGGHRIPG LNCCGQGRAC YRWSKRWLIV KDSFLLYMKP DSGAIAFVLL
310 320 330 340 350
VDKEFKIKVG KKETETKYGI RIDNLSRTLI LKCNSYRHAR WWGGAIEEFI
360 370 380 390 400
QKHGTNFLKD HRFGSYAAIQ ENALAKWYVN AKGYFEDVAN AMEEANEEIF
410 420 430 440 450
ITDWWLSPEI FLKRPVVEGN RWRLDCILKR KAQQGVRIFI MLYKEVELAL
460 470 480 490 500
GINSEYTKRT LMRLHPNIKV MRHPDHVSST VYLWAHHEKL VIIDQSVAFV
510 520 530 540 550
GGIDLAYGRW DDNEHRLTDV GSVKRVTSGP SLGSLPPAAM ESMESLRLKD
560 570 580 590 600
KNEPVQNLPI QKSIDDVDSK LKGIGKPRKF SKFSLYKQLH RHHLHDADSI
610 620 630 640 650
SSIDSTSNTG SIRSLQTGVG ELHGETRFWH GKDYCNFVFK DWVQLDKPFA
660 670 680 690 700
DFIDRYSTPR MPWHDIASAV HGKAARDVAR HFIQRWNFTK IMKSKYRSLS
710 720 730 740 750
YPFLLPKSQT TAHELRYQVP GSVHANVQLL RSAADWSAGI KYHEESIHAA
760 770 780 790 800
YVHVIENSRH YIYIENQFFI SCADDKVVFN KIGDAIAQRI LKAHRENQKY
810 820 830 840 850
RVYVVIPLLP GFEGDISTGG GNALQAIMHF NYRTMCRGEN SILGQLKAEL
860 870 880 890 900
GNQWINYISF CGLRTHAELE GNLVTELIYV HSKLLIADDN TVIIGSANIN
910 920 930 940 950
DRSMLGKRDS EMAVIVQDTE TVPSVMDGKE YQAGRFARGL RLQCFRVVLG
960 970 980 990 1000
YLDDPSEDIQ DPVSDKFFKE VWVSTAARNA TIYDKVFRCL PNDEVHNLIQ
1010 1020 1030 1040 1050
LRDFINKPVL AKEDPIRAEE ELKKIRGFLV QFPFYFLSEE SLLPSVGTKE

AIVPMEVWT
Length:1,059
Mass (Da):122,009
Last modified:April 26, 2005 - v1
Checksum:iBC5A4072C54AC053
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209907 mRNA. Translation: BAD93144.1.
RefSeqiNP_001123553.1. NM_001130081.2.
NP_002653.1. NM_002662.4.
UniGeneiHs.382865.
Hs.732969.

Genome annotation databases

GeneIDi5337.
KEGGihsa:5337.

Similar proteinsi

Entry informationi

Entry nameiQ59EA4_HUMAN
AccessioniPrimary (citable) accession number: Q59EA4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 22, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.