Q59E88 (Q59E88_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: DnaJ (Hsp40) homolog, subfamily A, member 3 variant EMBL BAD93160.1
Organism	Homo sapiens (Human) EMBL BAD93160.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	478 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat RuleBase RU003538
Ligand	Metal-binding RuleBase RU004484 Zinc RuleBase RU004484
Molecular function	Chaperone RuleBase RU003417
Gene Ontology (GO)
Biological_process	T cell differentiation in thymus Inferred from electronic annotation. Source: Compara activation-induced cell death of T cells Inferred from electronic annotation. Source: Compara cell aging Inferred from electronic annotation. Source: Compara embryo development Inferred from electronic annotation. Source: Compara mitochondrial DNA replication Inferred from electronic annotation. Source: Compara positive regulation of T cell proliferation Inferred from electronic annotation. Source: Compara protein folding Inferred from electronic annotation. Source: InterPro response to heat Inferred from electronic annotation. Source: InterPro skeletal muscle acetylcholine-gated channel clustering Inferred from electronic annotation. Source: Compara small GTPase mediated signal transduction Inferred from electronic annotation. Source: Compara
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara extrinsic to plasma membrane Inferred from electronic annotation. Source: Compara mitochondrion Inferred from electronic annotation. Source: Compara neuromuscular junction Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara postsynaptic membrane Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW small GTPase regulator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD93160.1

Sequences

	Sequence		Length	Mass (Da)
	Q59E88 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: F79D9A5FC3B18DD9	FASTA	478	52,286
	10 20 30 40 50 60 ARCSTRWLLV VVGTPRLPAI SGRGARPPRE GVVGAWLSRK LSVPAFASSL TSCGPRALLT 70 80 90 100 110 120 LRPGVSLTGT KHNPFICTAS FHTSAPLAKE DYYQILGVPR NASQKEIKKA YYQLAKKYHP 130 140 150 160 170 180 DTNKDDPKAK EKFSQLAEAY EVLSDEVKRK QYDAYGSAGF DPGASGSQHS YWKGGPTVDP 190 200 210 220 230 240 EELFRKIFGE FSSSSFGDFQ TVFDQPQEYF MELTFNQAAK GVNKEFTVNI MDTCERCNGK 250 260 270 280 290 300 GNEPGTKVQH CHYCGGSGME TINTGPFVMR STCRRCGGRG SIIISPCVVC RGAGQAKQKK 310 320 330 340 350 360 RVMIPVPAGV EDGQTVRMPV GKREIFITFR VQKSPVFRRD GADIHSDLFI SIAQALLGGT 370 380 390 400 410 420 ARAQGLYETI NVTIPPGTQT DQKIRMGGKG IPRINSYGYG DHYIHIKIRV PKRLTSRQQS 430 440 450 460 470 LILSYAEDET DVEGTVNGVT LTSSGGSTMD SSAGSKARRE AGEDEEGFLS KLKKMFTS

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Aorta endothelial cell EMBL BAD93160.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209923 mRNA. Translation: BAD93160.1.
IPI	IPI00294610.
RefSeq	NP_005138.3. NM_005147.5.
UniGene	Hs.744096.
3D structure databases
ProteinModelPortal	Q59E88.
ModBase	Search...
Proteomic databases
PRIDE	Q59E88.
Protocols and materials databases
DNASU	9093.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9093.
KEGG	hsa:9093.
Organism-specific databases
CTD	9093.
Phylogenomic databases
HOVERGEN	HBG051371.
KO	K09504.
Gene expression databases
ArrayExpress	Q59E88.
Bgee	Q59E88.
Family and domain databases
Gene3D	1.10.287.110. 1 hit. 2.10.230.10. 1 hit.
HAMAP	MF_01152. DnaJ.
InterPro	IPR012724. DnaJ. IPR002939. DnaJ_C. IPR001623. DnaJ_domain. IPR018253. DnaJ_domain_CS. IPR008971. HSP40/DnaJ_pept-bd. IPR001305. HSP_DnaJ_Cys-rich_dom. [Graphical view]
Pfam	PF00226. DnaJ. 1 hit. PF01556. DnaJ_C. 1 hit. PF00684. DnaJ_CXXCXGXG. 1 hit. [Graphical view]
PRINTS	PR00625. JDOMAIN.
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
SUPFAM	SSF46565. DnaJ_N. 1 hit. SSF49493. HSP40_DnaJ_pep. 2 hits. SSF57938. HSP_DnaJ_cys-rich. 1 hit.
PROSITE	PS00636. DNAJ_1. 1 hit. PS50076. DNAJ_2. 1 hit. PS51188. ZF_CR. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	9093.
NextBio	34071.

Entry information

Entry name

Q59E88_HUMAN

Accession

Primary (citable) accession number: Q59E88

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 29, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.