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Q59E88

- Q59E88_HUMAN

UniProt

Q59E88 - Q59E88_HUMAN

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Protein
Submitted name: DnaJ (Hsp40) homolog, subfamily A, member 3 variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. small GTPase regulator activity Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. T cell differentiation in thymus Source: Ensembl
  2. activation-induced cell death of T cells Source: Ensembl
  3. cell aging Source: Ensembl
  4. embryo development Source: Ensembl
  5. mitochondrial DNA replication Source: Ensembl
  6. positive regulation of T cell proliferation Source: Ensembl
  7. protein folding Source: InterPro
  8. response to heat Source: InterPro
  9. skeletal muscle acetylcholine-gated channel clustering Source: Ensembl
  10. small GTPase mediated signal transduction Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotation

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DnaJ (Hsp40) homolog, subfamily A, member 3 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. extrinsic component of plasma membrane Source: Ensembl
  3. intracellular membrane-bounded organelle Source: HPA
  4. mitochondrion Source: HPA
  5. neuromuscular junction Source: Ensembl
  6. nucleus Source: Ensembl
  7. postsynaptic membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ59E88.

Expressioni

Gene expression databases

ArrayExpressiQ59E88.
BgeeiQ59E88.

Structurei

3D structure databases

ProteinModelPortaliQ59E88.

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation

Phylogenomic databases

HOVERGENiHBG051371.
KOiK09504.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
HAMAPiMF_01152. DnaJ.
InterProiIPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
[Graphical view]
PfamiPF01556. CTDII. 1 hit.
PF00226. DnaJ. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 1 hit.
SSF57938. SSF57938. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59E88-1 [UniParc]FASTAAdd to Basket

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ARCSTRWLLV VVGTPRLPAI SGRGARPPRE GVVGAWLSRK LSVPAFASSL    50
TSCGPRALLT LRPGVSLTGT KHNPFICTAS FHTSAPLAKE DYYQILGVPR 100
NASQKEIKKA YYQLAKKYHP DTNKDDPKAK EKFSQLAEAY EVLSDEVKRK 150
QYDAYGSAGF DPGASGSQHS YWKGGPTVDP EELFRKIFGE FSSSSFGDFQ 200
TVFDQPQEYF MELTFNQAAK GVNKEFTVNI MDTCERCNGK GNEPGTKVQH 250
CHYCGGSGME TINTGPFVMR STCRRCGGRG SIIISPCVVC RGAGQAKQKK 300
RVMIPVPAGV EDGQTVRMPV GKREIFITFR VQKSPVFRRD GADIHSDLFI 350
SIAQALLGGT ARAQGLYETI NVTIPPGTQT DQKIRMGGKG IPRINSYGYG 400
DHYIHIKIRV PKRLTSRQQS LILSYAEDET DVEGTVNGVT LTSSGGSTMD 450
SSAGSKARRE AGEDEEGFLS KLKKMFTS 478
Length:478
Mass (Da):52,286
Last modified:May 10, 2005 - v1
Checksum:iF79D9A5FC3B18DD9
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209923 mRNA. Translation: BAD93160.1.
RefSeqiNP_005138.3. NM_005147.5.
UniGeneiHs.459779.

Genome annotation databases

GeneIDi9093.
KEGGihsa:9093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209923 mRNA. Translation: BAD93160.1 .
RefSeqi NP_005138.3. NM_005147.5.
UniGenei Hs.459779.

3D structure databases

ProteinModelPortali Q59E88.
ModBasei Search...

Proteomic databases

PRIDEi Q59E88.

Protocols and materials databases

DNASUi 9093.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9093.
KEGGi hsa:9093.

Organism-specific databases

CTDi 9093.

Phylogenomic databases

HOVERGENi HBG051371.
KOi K09504.

Miscellaneous databases

GenomeRNAii 9093.
NextBioi 34071.

Gene expression databases

ArrayExpressi Q59E88.
Bgeei Q59E88.

Family and domain databases

Gene3Di 1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
HAMAPi MF_01152. DnaJ.
InterProi IPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
[Graphical view ]
Pfami PF01556. CTDII. 1 hit.
PF00226. DnaJ. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
[Graphical view ]
PRINTSi PR00625. JDOMAIN.
SMARTi SM00271. DnaJ. 1 hit.
[Graphical view ]
SUPFAMi SSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 1 hit.
SSF57938. SSF57938. 1 hit.
PROSITEi PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Aorta endothelial cellImported.

Entry informationi

Entry nameiQ59E88_HUMAN
AccessioniPrimary (citable) accession number: Q59E88
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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