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Protein
Submitted name:

CholecystoKinin Receptor homolog

Gene

ckr-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
CholecystoKinin Receptor homologImported
Gene namesi
Name:ckr-2Imported
ORF Names:CELE_Y39A3B.5Imported, Y39A3B.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY39A3B.5c; CE38443; WBGene00021439; ckr-2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 44HelicalSequence analysisAdd BLAST24
Transmembranei65 – 87HelicalSequence analysisAdd BLAST23
Transmembranei93 – 114HelicalSequence analysisAdd BLAST22
Transmembranei135 – 157HelicalSequence analysisAdd BLAST23
Transmembranei183 – 204HelicalSequence analysisAdd BLAST22
Transmembranei296 – 319HelicalSequence analysisAdd BLAST24
Transmembranei339 – 361HelicalSequence analysisAdd BLAST23
Transmembranei382 – 401HelicalSequence analysisAdd BLAST20
Transmembranei413 – 434HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ59E84.

Expressioni

Gene expression databases

BgeeiWBGene00021439.
ExpressionAtlasiQ59E84. differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y39A3B.5d.

Structurei

3D structure databases

ProteinModelPortaliQ59E84.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 358G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST324

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00860000133695.
HOGENOMiHOG000020523.

Family and domain databases

InterProiIPR009126. Cholcskin_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01822. CCYSTOKININR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59E84-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTVHQEEIC RFRGTTENYT IAVTFFMIFL LSVVGNSVVL IVIIKQRAMR
60 70 80 90 100
SITNIYLMNL AASDMMLSVV CMPPTLVSMV MNCWMFGNYM CKILAYLQPV
110 120 130 140 150
VVTASAYTLA VIAFERYFAI CKPLHSRIWQ TRSHAYAMIT LVWVIAIAAN
160 170 180 190 200
ILMLFMYEQQ TYSSNGYTCA PIHPPIYHFA YQVYMTVVLL VIPLVVMAGL
210 220 230 240 250
YGNVITSLKS GIKLEIASVD PPLATATTTA IVASMTDEQK LSFWNKLSNK
260 270 280 290 300
LTFSQQDKTV QHPNFGHRKS DTSICLENPS LRSTHTQKSA MAKQRVIKML
310 320 330 340 350
IVVVIIFFCC WTPSYIWWLL LIAGDSFQSL NLSVWNSDIN TFITLLTYIS
360 370 380 390 400
SCTNPITYCF LNKKFRNAVY ATFGRKKNMR HHFQKVYFDI FELLIFFKIN
410 420 430 440 450
YQKSIKSPVS VFSNYLFFGF SAPLISVNLS LILFRSTFRS TAELITLTKE
460 470
SRDKLLTGTN THKFVVISLF V
Length:471
Mass (Da):53,739
Last modified:April 26, 2005 - v1
Checksum:i051A2B8595E9C586
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD73015.1.
RefSeqiNP_001022844.1. NM_001027673.3.
UniGeneiCel.9837.

Genome annotation databases

EnsemblMetazoaiY39A3B.5c; Y39A3B.5c; WBGene00021439.
GeneIDi175341.
UCSCiY39A3B.5c. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD73015.1.
RefSeqiNP_001022844.1. NM_001027673.3.
UniGeneiCel.9837.

3D structure databases

ProteinModelPortaliQ59E84.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.Y39A3B.5d.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ59E84.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY39A3B.5c; Y39A3B.5c; WBGene00021439.
GeneIDi175341.
UCSCiY39A3B.5c. c. elegans.

Organism-specific databases

CTDi175341.
WormBaseiY39A3B.5c; CE38443; WBGene00021439; ckr-2.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00860000133695.
HOGENOMiHOG000020523.

Gene expression databases

BgeeiWBGene00021439.
ExpressionAtlasiQ59E84. differential.

Family and domain databases

InterProiIPR009126. Cholcskin_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01822. CCYSTOKININR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ59E84_CAEEL
AccessioniPrimary (citable) accession number: Q59E84
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.