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Protein

Probable RNA polymerase sigma-C factor

Gene

sigC

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi362 – 38120H-T-H motifBy similarityAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable RNA polymerase sigma-C factor
Gene namesi
Name:sigC
Ordered Locus Names:sll0184
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Probable RNA polymerase sigma-C factorPRO_0000093937Add
BLAST

Proteomic databases

PaxDbiQ59996.

Interactioni

Protein-protein interaction databases

IntActiQ59996. 13 interactions.
STRINGi1148.sll0184.

Structurei

3D structure databases

ProteinModelPortaliQ59996.
SMRiQ59996. Positions 145-236.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi193 – 20614Polymerase core bindingAdd
BLAST

Sequence similaritiesi

Belongs to the sigma-70 factor family.Curated

Phylogenomic databases

eggNOGiCOG0568.
HOGENOMiHOG000270273.
InParanoidiQ59996.
KOiK03087.
OMAiAQKVQRY.
OrthoDBiEOG6XHC70.
PhylomeDBiQ59996.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR009042. RNA_pol_sigma70_r1_2.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR017848. RNA_pol_sigma_RpoD_cyanobac.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00140. Sigma70_r1_2. 1 hit.
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02997. Sig70-cyanoRpoD. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59996-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPSNDEPP LTNVRDLEAM LPLEEEDLTA DSQDLEYTAV AHRQQFSTDL
60 70 80 90 100
VRLYLQDIGR IPLLKRDEEV HIAQQVQSYL RLVEIQNRAA ESDAAIDQYQ
110 120 130 140 150
TAIAVHDQLL VQLGHRPSYE RWAKILGQTV ATLKQTLKSG KKRWAELAGL
160 170 180 190 200
TVEELENIEK QGITAKAHMI KANLRLVVSV AKKYQNRGLE LLDLIQEGTL
210 220 230 240 250
GLERAVEKFD PTKGYRFSTY SYWWIRQGIT RAIATQSRMI RLPVHITEKL
260 270 280 290 300
NKIKRAQRKI SQEKGHTPKI DEVAEELGMT PEQVREVLTQ VPRSVSLELK
310 320 330 340 350
VGQDKDTELM DLLETDTQSP EDELMREALQ NDMQEILLDL TPREQEVIAL
360 370 380 390 400
RFGFQDGVAH SLSEIGRILN LSRERVRQIE AKALQKLRHP RRRDRIRDYY

ENLG
Length:404
Mass (Da):46,581
Last modified:October 31, 1997 - v1
Checksum:iCDCBE67BF031D0F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10419.1.
PIRiS76573.
RefSeqiNP_442349.1. NC_000911.1.
YP_005652409.1. NC_017277.1.
YP_007452225.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA10419; BAA10419; BAA10419.
KEGGisyn:sll0184.
PATRICi23842374. VBISynSp132158_2727.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA10419.1.
PIRiS76573.
RefSeqiNP_442349.1. NC_000911.1.
YP_005652409.1. NC_017277.1.
YP_007452225.1. NC_020286.1.

3D structure databases

ProteinModelPortaliQ59996.
SMRiQ59996. Positions 145-236.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ59996. 13 interactions.
STRINGi1148.sll0184.

Proteomic databases

PaxDbiQ59996.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10419; BAA10419; BAA10419.
KEGGisyn:sll0184.
PATRICi23842374. VBISynSp132158_2727.

Phylogenomic databases

eggNOGiCOG0568.
HOGENOMiHOG000270273.
InParanoidiQ59996.
KOiK03087.
OMAiAQKVQRY.
OrthoDBiEOG6XHC70.
PhylomeDBiQ59996.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR009042. RNA_pol_sigma70_r1_2.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR017848. RNA_pol_sigma_RpoD_cyanobac.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00140. Sigma70_r1_2. 1 hit.
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
[Graphical view]
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02997. Sig70-cyanoRpoD. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiRPSC_SYNY3
AccessioniPrimary (citable) accession number: Q59996
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1997
Last sequence update: October 31, 1997
Last modified: March 31, 2015
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.