Reviewed, UniProtKB/Swiss-Prot Q59979 (DEXT_STRSL)

Names and origin

Protein names

Recommended name:
    Dextranase
    EC=3.2.1.11
Alternative name(s):
    Alpha-1,6-glucan-6-glucanohydrolase

Gene names

Name:	dex
Synonyms:	dexS

Organism

Streptococcus salivarius

Taxonomic identifier

1304 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	822 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->6)-alpha-D-glucosidic linkages in dextran.
Sequence similarities	Belongs to the glycosyl hydrolase 66 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	dextranase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 38	38	Potential
	Chain	39 – 822	784	Dextranase		PRO_0000012240

Sequences

	Sequence		Length	Mass (Da)
	Q59979-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 31857D38D3F2C761	FASTA	822	87,924
	10 20 30 40 50 60 MTVNLTLQHA SEIIGQDNVD LTLAAGASAK VSNLTVASEW LTNNTGYLVT ISVNDKSGNV 70 80 90 100 110 120 LSSKRAGLSV EDDWTVFPRY GIVAGSPTDQ NSILVKNLEA YRKELELMKS MNINSYFFYD 130 140 150 160 170 180 AYNEATDPFP EGVDSFVQKW NTWSHTQVDT KAVKELVDQV HKSGAVAMLY NMISADSNPK 190 200 210 220 230 240 NPALPLAALA YNFYDSFGKK GEPMTYTIGD NPTQVYYDPA NPDWQKYIAG VMKSAMDRMG 250 260 270 280 290 300 FDGWQGDTIG DNRVTDYEHR NSTDEADSHM MSDSYASFIN AMKDLIGEKY YITINDVNGG 310 320 330 340 350 360 NDDKLAKARQ DVVYNELWTN GGSVIPGRMQ VAYGDLKARI DMVRNKTGKS LIVGAYMEEP 370 380 390 400 410 420 GIDYTVPGGK ATNGAGKDAL AGKPLQADAT LLVDATVAAA GGYHMSIAAL ANANAALNVL 430 440 450 460 470 480 QSAYYPTQYL SVAKDTIRKL YNYQQFITAY ENLLRGEGVT NSTQAVSTKN ASGEILSKDA 490 500 510 520 530 540 LGVTGDQVWT FAKSGKGFST VQMINMMGIN AGWHNEEGYA DNKTPDAQEN LTVRLSLAGK 550 560 570 580 590 600 TAQEAAKIAD QVYVTSPDDW ATSSMKKAQA SLETDENGQP VLVISVPKLT LWNMLYIKED 610 620 630 640 650 660 TTATPVEPVT NQAGKKVDNT VTSEASSETA KSENTTVNKG SEAPTDTKPS VEAPKLDETT 670 680 690 700 710 720 KPAPSVDELV NSAAVPVAIA VSETAHDKKD DNSVSNTDQG TVASDSITTP ASEAASTAAS 730 740 750 760 770 780 TVSSEVSESV TVSSEPSETE NSSEASTSES ATPTTTAISE SHAVVEPVAS LTESESQAST 790 800 810 820 SLVSETTSTI VSVAPSEVSE STSEEVILMD YQKTSIVGID SL

References

[1]	"Cloning and sequencing of the gene coding for dextranase from Streptococcus salivarius." Ohnishi Y., Kubo S., Ono Y., Nozaki M., Gonda Y., Okano H., Matsuya T., Matsushiro A., Morita T. Gene 156:93-96(1995) [PubMed: 7737522] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: M-33.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D29644 Genomic DNA. Translation: BAA06127.1.
PIR	JC4076.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH66. Glycoside Hydrolase Family 66.
Enzyme and pathway databases
BRENDA	3.2.1.11. 39093.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

DEXT_STRSL

Accession

Primary (citable) accession number: Q59979

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	April 14, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)