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Q59977 (CISY_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Citrate synthase

EC=2.3.3.16
Gene names
Name:gltA
Ordered Locus Names:sll0401
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Sequence similarities

Belongs to the citrate synthase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Citrate synthase
PRO_0000169974

Sites

Active site2661 By similarity
Active site3201 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q59977 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: CD0A4A41F617F27E

FASTA39744,831
        10         20         30         40         50         60 
MNYMMTDNEV FKEGLAGVPA AKSRVSHVDG TDGILEYRGI RIEELAKSSS FIEVAYLLIW 

        70         80         90        100        110        120 
GKLPTQAEIE EFEYEIRTHR RIKYHIRDMM KCFPETGHPM DALQTSAAAL GLFYARRALD 

       130        140        150        160        170        180 
DPKYIRAAVV RLLAKIPTMV AAFHMIREGN DPIQPNDKLD YASNFLYMLT EKEPDPFAAK 

       190        200        210        220        230        240 
VFDVCLTLHA EHTMNASTFS ARVTASTLTD PYAVVASAVG TLAGPLHGGA NEEVLNMLEE 

       250        260        270        280        290        300 
IGSVENVRPY VEKCLANKQR IMGFGHRVYK VKDPRAIILQ DLAEQLFAKM GHDEYYEIAV 

       310        320        330        340        350        360 
ELEKVVEEYV GQKGIYPNVD FYSGLVYRKL DIPADLFTPL FAIARVAGWL AHWKEQLSVN 

       370        380        390 
KIYRPTQIYI GDHNLSYVPM TERVVSVARN EDPNAII 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27184 / PCC 6803 / N-1.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA10262.1.
PIRS74344.
RefSeqNP_442192.1. NC_000911.1.
YP_005652251.1. NC_017277.1.
YP_007452068.1. NC_020286.1.

3D structure databases

ProteinModelPortalQ59977.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ59977. 2 interactions.
STRING1148.sll0401.

Proteomic databases

PaxDbQ59977.
PRIDEQ59977.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA10262; BAA10262; BAA10262.
GeneID952604.
KEGGsyn:sll0401.
syy:SYNGTS_2298.
syz:MYO_123220.
PATRIC23842006. VBISynSp132158_2545.

Phylogenomic databases

eggNOGCOG0372.
HOGENOMHOG000021225.
KOK01647.
OMASCKSRIT.
OrthoDBEOG6P8TP4.
PhylomeDBQ59977.

Enzyme and pathway databases

UniPathwayUPA00223; UER00717.

Family and domain databases

Gene3D1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProIPR011278. 2-MeCitrate/Citrate_synth_I.
IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
[Graphical view]
PANTHERPTHR11739. PTHR11739. 1 hit.
PfamPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001369. Citrate_synth. 1 hit.
PRINTSPR00143. CITRTSNTHASE.
SUPFAMSSF48256. SSF48256. 1 hit.
TIGRFAMsTIGR01800. cit_synth_II. 1 hit.
PROSITEPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCISY_SYNY3
AccessionPrimary (citable) accession number: Q59977
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways