Q59967 (SRPH_SYNE7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine acetyltransferase, plasmid
Short name=SAT
EC=2.3.1.30

Gene names

Name:	srpH
Ordered Locus Names:	Synpcc7942_B2663
ORF Names:	pANL39

Encoded on

Plasmid pANL

Organism

Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) [Complete proteome] [HAMAP]

Taxonomic identifier

1140 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
Pathway	Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the transferase hexapeptide repeat family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis
Cellular component	Cytoplasm
Domain	Repeat
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	cysteine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Serine acetyltransferase, plasmid		PRO_0000068688

Sequences

	Sequence		Length	Mass (Da)
	Q59967 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 00BB74D8AABB1E70	FASTA	319	34,570
	10 20 30 40 50 60 MSLSPRSDRT EIRRSWGLDS IVSALSQAST DPLPHHLLSD QFYPLPSRES LGLILHGLRS 70 80 90 100 110 120 VLFPRHFGDP ELSVETTHYF IGNTLDKTLN LLNEQIRREL WLQHVTQGTP EATPAVLSQH 130 140 150 160 170 180 ASELTQAFAQ ALPEIKRLLD SDVNAAYLGD PAAQSISEIL FCYPGITAIT FHRLAHRLYQ 190 200 210 220 230 240 LGLPLLARIT AEVSHSETGI DIHPGAAIGG SFFIDHGTGV VIGETCVIGD RVRIYQAVTL 250 260 270 280 290 300 GAKSFPRDET GALIKGQARH PVIEDDVVIY AGATLLGRIT VGRGSTIGGN VWLTRSVPAG 310 SFISQAQIRS DNFESGGGI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Two enzymes together capable of cysteine biosynthesis are encoded on a cyanobacterial plasmid." Nicholson M.L., Gaasenbeek M., Laudenbach D.E. Mol. Gen. Genet. 247:623-632(1995) [PubMed: 7603442] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"pANL, the large plasmid of Synechococcus elongatus PCC 7942." Holtman C.K., Chen Y., Sandoval P., Socias T., Mohler B.J., Youderian P., Golden S.S. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Complete sequence of plasmid 1 of Synechococcus elongatus PCC 7942." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7942.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U23436 Genomic DNA. Translation: AAA86726.1. AF441790 Genomic DNA. Translation: AAM81165.1. CP000101 Genomic DNA. Translation: ABB58692.1.
RefSeq	NP_665778.1. NC_004073.2. YP_398712.1. NC_007595.1.
3D structure databases
ProteinModelPortal	Q59967.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59967.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1010217. 3772772.
GenomeReviews	Gene locus Synpcc7942_B2663 in contig CP000101_GR.
KEGG	syf:Synpcc7942_B2663.
PATRIC	23784916. VBISynElo51371_0009.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1045.
HOGENOM	HBG754554.
PhylomeDB	Q59967.
ProtClustDB	CLSK904121.
Enzyme and pathway databases
BioCyc	SYNEL:SYNPCC7942_B2663-MONOMER.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00640.
Pfam	PF00132. Hexapep. 1 hit. [Graphical view]
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SRPH_SYNE7

Accession

Primary (citable) accession number: Q59967
Secondary accession number(s): Q7BA85

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program