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Protein

RNA polymerase sigma factor SigA

Gene

sigA

Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.SAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi336 – 355H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor SigAUniRule annotation
Gene namesi
Name:sigAUniRule annotationImported
Synonyms:rpoDImported
Ordered Locus Names:SYNPCC7002_A2014Imported
OrganismiSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)Imported
Taxonomic identifieri32049 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001688 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Interacts transiently with the RNA polymerase catalytic core.UniRule annotation

Protein-protein interaction databases

STRINGi32049.SYNPCC7002_A2014

Structurei

3D structure databases

ProteinModelPortaliQ59965
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini167 – 180RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini335 – 361RNA_pol_sigma70InterPro annotationAdd BLAST27

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni143 – 213Sigma-70 factor domain-2UniRule annotationAdd BLAST71
Regioni310 – 363Sigma-70 factor domain-4UniRule annotationAdd BLAST54

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili79 – 108Sequence analysisAdd BLAST30

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi167 – 170Interaction with polymerase core subunit RpoCUniRule annotation4

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105DG1 Bacteria
COG0568 LUCA
HOGENOMiHOG000270273
KOiK03086
OMAiIRVYLQE
OrthoDBiPOG091H0012

Family and domain databases

Gene3Di1.10.10.10, 2 hits
HAMAPiMF_00963 Sigma70_RpoD_SigA, 1 hit
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR009042 RNA_pol_sigma70_r1_2
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR012760 RNA_pol_sigma_RpoD_C
IPR017848 RNA_pol_sigma_RpoD_cyanobac
IPR028630 Sigma70_RpoD
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00140 Sigma70_r1_2, 1 hit
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02393 RpoD_Cterm, 1 hit
TIGR02997 Sig70-cyanoRpoD, 1 hit
TIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q59965-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQATNPVLD QTRNEGDIDY SALAEAQIKE GTDYVELTLP TKKSRKAKTS
60 70 80 90 100
RRKETATKKK PYTEDSIRIY LQEIGRIRLL RAEEEIELAR KIADLLELER
110 120 130 140 150
MREQLTEHES RVPTDKEWAE AAGMPLKDFR RRLFHGRRAK DKMVQSNLRL
160 170 180 190 200
VVSIAKKYMN RGLSFQDLIQ EGSLGLIRAA EKFDHEKGYK FSTYATWWIR
210 220 230 240 250
QAITRAIADQ SRTIRLPVHL YETISRIKKT TKILSQELGR KPTEEEIAER
260 270 280 290 300
MEMTIEKLRF IAKSAQLPIS LETPIGKEED SRLGDFIEAD GETPEDQVSK
310 320 330 340 350
SLLREDLENV LDTLSARERD VLRLRYGLDD GRMKTLEEIG QIFNVTRERI
360 370
RQIEAKALRK LRHPNRNSIL KEYIR
Length:375
Mass (Da):43,740
Last modified:November 1, 1996 - v1
Checksum:i1E3FC5C369D16DB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15574 Genomic DNA Translation: AAB41506.1
CP000951 Genomic DNA Translation: ACB00001.1
RefSeqiWP_012307623.1, NC_010475.1

Genome annotation databases

EnsemblBacteriaiACB00001; ACB00001; SYNPCC7002_A2014
KEGGisyp:SYNPCC7002_A2014

Similar proteinsi

Entry informationi

Entry nameiQ59965_SYNP2
AccessioniPrimary (citable) accession number: Q59965
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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