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Protein

Alpha-amylase

Gene

amy

Organism
Streptomyces sp.
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:amyImported
OrganismiStreptomyces sp.Imported
Taxonomic identifieri1931 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence analysisAdd
BLAST
Chaini32 – 459428Alpha-amylaseSequence analysisPRO_5004252395Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ59964.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 365328AamyInterPro annotationAdd
BLAST
Domaini374 – 45784Aamy_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59964-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQHRFRLIGG TLAGVLTVAG LTTLAPWQSQ ATPPGEKTVT VTMFERPYAD
60 70 80 90 100
VASACTDQLG PAGYGYVQVS PATEHIQGDQ WWTSYQPVSY RIAGRLGDRD
110 120 130 140 150
GFAAMVDACH SAGVKVVADA VINHMAAGSG TGTGGTAYTK YDYPGYFGDA
160 170 180 190 200
DFHTCRTAIK DYTDRGDVQN CELVGLSDLD TGKDEVRSTI AAYLDGLRSM
210 220 230 240 250
GVDGFRIDAA KHMAADDVAI QGQDERPPGS GSPEVIQGGG EAVQPEEYTE
260 270 280 290 300
IGDVDEFRYG GHLKSAFQGG GIAQLKAVAD RKLGSASART FVDNWDTERN
310 320 330 340 350
GSTLTYKDGA AYTLANVFML ASPYGSPNVY SGYEWSDADA GPPSGADGWT
360 370 380 390 400
DTHAQQTITG LVGFRNAVGS AELTDWWDNG GSALAFGRGD KGFVALNNAD
410 420 430 440 450
DALTETFTTS LPAGTYCNVA AASPDDCDGN TVTVGDDGAV QATVPARGAL

ALHTGAQAG
Length:459
Mass (Da):47,975
Last modified:November 1, 1996 - v1
Checksum:i8D916FDD2CAC1275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08602 Genomic DNA. Translation: AAA82875.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08602 Genomic DNA. Translation: AAA82875.1.

3D structure databases

ProteinModelPortaliQ59964.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of an alpha-amylase gene from Streptomyces sp WL6."
    Chen I., Marcos A.T., da Costa S.O., Martin J.F., Padilla G.
    Biochem. Mol. Biol. Int. 35:1059-1067(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WL6Imported.

Entry informationi

Entry nameiQ59964_STRSQ
AccessioniPrimary (citable) accession number: Q59964
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.