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Protein

RNA polymerase principal sigma factor HrdD

Gene

hrdD

Organism
Streptomyces griseus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi294 – 313H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Sigma factor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase principal sigma factor HrdD
Gene namesi
Name:hrdD
OrganismiStreptomyces griseus
Taxonomic identifieri1911 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000939951 – 332RNA polymerase principal sigma factor HrdDAdd BLAST332

Structurei

3D structure databases

ProteinModelPortaliQ59914
SMRiQ59914
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi124 – 137Polymerase core bindingAdd BLAST14

Sequence similaritiesi

Belongs to the sigma-70 factor family.Curated

Family and domain databases

Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR009042 RNA_pol_sigma70_r1_2
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00140 Sigma70_r1_2, 1 hit
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q59914-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATRAVARRQ PAASGETGAA GSVRATGEIA DRDLVGMYLD EIARTPLLDA
60 70 80 90 100
AKEVELSQTI EAGVYAGKIL DGEVDSDSAG ASREELEALV AEGERAKDVF
110 120 130 140 150
IRSNLRLVVA VARRYPRSGL PLLDLIQEGN AGLVRAVEKF DYAKGFKFST
160 170 180 190 200
YATWWIRQAI TRSIADQSRT IRLPVHLVEE LGRIRRVQRE FNRENGRDPE
210 220 230 240 250
PAEIAAELSS TPERVTDVLD WARDPVSLNM SVDDEGETQF GDLLEDTSAV
260 270 280 290 300
SPEQSVLTLL RSEELDDLIG QLDDRTASII KMRYGIEDGR ERTLTEVGKQ
310 320 330
HGLTRERIRQ IEKHALLELK RMAHDTGFDA AA
Length:332
Mass (Da):36,769
Last modified:November 1, 1996 - v1
Checksum:iA5807F38CEDB0838
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79980 Genomic DNA Translation: CAA56305.1
PIRiS49185

Similar proteinsi

Entry informationi

Entry nameiHRDD_STRGR
AccessioniPrimary (citable) accession number: Q59914
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health