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Protein

1,4-alpha-glucan branching enzyme GlgB 2

Gene

glgB2

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.By similarity

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei421NucleophileBy similarity1
Active sitei474Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB 2 (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2
Alpha-(1->4)-glucan branching enzyme 2
Glycogen branching enzyme 2
Short name:
BE 2
Gene namesi
Name:glgB2
Synonyms:glgBII
Ordered Locus Names:SCO7332
ORF Names:SC4G10.11c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887501 – 7411,4-alpha-glucan branching enzyme GlgB 2Add BLAST741

Proteomic databases

PRIDEiQ59832

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi100226.SCO7332

Structurei

3D structure databases

ProteinModelPortaliQ59832
SMRiQ59832
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA
HOGENOMiHOG000283037
InParanoidiQ59832
KOiK00700
OMAiDKRRQPI
OrthoDBiPOG091H08D1
PhylomeDBiQ59832

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 2 hits
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q59832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRDTSIPE PSGPVPPAPG ACATAPPLDP TDRGRLLAGA HHDPHSLLGA
60 70 80 90 100
HPVPGGIAFR VLRPFAREVG VVVDGERHTL ASEEDGLFSG VLPLAGIPSY
110 120 130 140 150
TLVVAYEQGE TQETHDPYRF LPALGELDLH LIGEGRHEQL WQALGAEPMT
160 170 180 190 200
HEGVTGTRFT VWAPNAQGVR VATDFTHWDG TAFPMRSLGS SGVWELFLPG
210 220 230 240 250
VGEGTRYKFE IHSRYGHRFL KADPMARAAE EPPNTASVVT ASRYEWGDAQ
260 270 280 290 300
WMRTRADTPV HEAPFSVYEV HLPSWRPGLT YRELAEELPA YVKDLGFTHV
310 320 330 340 350
ELMPVAEHPY GPSWGYQVTG FYAPTARLGS PDDFRFLVDA LHRAGIGVIM
360 370 380 390 400
DWVPAHFPKD DWALGRFDGD PLYEPGDSRR AEHPDWGTYT FDFARTEVRN
410 420 430 440 450
FLVANAVYWC EEFHIDGLRV DAVASMLYLD YSRDSGQWEP NQYGGREDLA
460 470 480 490 500
AMAFLQEMNA TVYRRCPGVV TIAEESTAWG GVTRPTDTGG LGFGLKWNMG
510 520 530 540 550
WMHDSLEYVA HEPVHRRYHH HEMTFSMVYA YSENYVLPIS HDEVVHGKQA
560 570 580 590 600
LVSKMPGDWW QRRANVRAYL GFMWAHPGKQ LLFMGQEFAQ GAEWSEKQGP
610 620 630 640 650
EWWLLDEGYH SAGDHRGVQD LVRELNTRYT RTPALWQRDT DPAGFRWVSV
660 670 680 690 700
DAAEDNVFAF LRYGTDGTPL LAVSNFSPVV RHEYGLAVGD EAVAWQEVLN
710 720 730 740
TDAEEYGGGG VGNPDPVKPE DGSIRITLPP LATVWLMPYA L
Length:741
Mass (Da):82,776
Last modified:August 15, 2003 - v2
Checksum:i5FB7A44120677759
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti561Q → H in CAA52109 (PubMed:8596463).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73903 Genomic DNA Translation: CAA52109.1
AL939131 Genomic DNA Translation: CAB92878.1
PIRiS70078 S34218
RefSeqiNP_631386.1, NC_003888.3
WP_011031592.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAB92878; CAB92878; CAB92878
GeneIDi1102770
KEGGisco:SCO7332
PATRICifig|100226.15.peg.7436

Similar proteinsi

Entry informationi

Entry nameiGLGB2_STRCO
AccessioniPrimary (citable) accession number: Q59832
Secondary accession number(s): Q9KY06
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: August 15, 2003
Last modified: May 23, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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