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Q59832

- GLGB2_STRCO

UniProt

Q59832 - GLGB2_STRCO

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Protein

1,4-alpha-glucan branching enzyme GlgB 2

Gene
glgB2, glgBII, SCO7332, SC4G10.11c
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei421 – 4211Nucleophile By similarity
Active sitei474 – 4741Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB 2 (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2
Alpha-(1->4)-glucan branching enzyme 2
Glycogen branching enzyme 2
Short name:
BE 2
Gene namesi
Name:glgB2
Synonyms:glgBII
Ordered Locus Names:SCO7332
ORF Names:SC4G10.11c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7417411,4-alpha-glucan branching enzyme GlgB 2UniRule annotationPRO_0000188750Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi100226.SCO7332.

Structurei

3D structure databases

ProteinModelPortaliQ59832.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiHENIENP.
OrthoDBiEOG6JX7GT.
PhylomeDBiQ59832.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59832-1 [UniParc]FASTAAdd to Basket

« Hide

MALRDTSIPE PSGPVPPAPG ACATAPPLDP TDRGRLLAGA HHDPHSLLGA    50
HPVPGGIAFR VLRPFAREVG VVVDGERHTL ASEEDGLFSG VLPLAGIPSY 100
TLVVAYEQGE TQETHDPYRF LPALGELDLH LIGEGRHEQL WQALGAEPMT 150
HEGVTGTRFT VWAPNAQGVR VATDFTHWDG TAFPMRSLGS SGVWELFLPG 200
VGEGTRYKFE IHSRYGHRFL KADPMARAAE EPPNTASVVT ASRYEWGDAQ 250
WMRTRADTPV HEAPFSVYEV HLPSWRPGLT YRELAEELPA YVKDLGFTHV 300
ELMPVAEHPY GPSWGYQVTG FYAPTARLGS PDDFRFLVDA LHRAGIGVIM 350
DWVPAHFPKD DWALGRFDGD PLYEPGDSRR AEHPDWGTYT FDFARTEVRN 400
FLVANAVYWC EEFHIDGLRV DAVASMLYLD YSRDSGQWEP NQYGGREDLA 450
AMAFLQEMNA TVYRRCPGVV TIAEESTAWG GVTRPTDTGG LGFGLKWNMG 500
WMHDSLEYVA HEPVHRRYHH HEMTFSMVYA YSENYVLPIS HDEVVHGKQA 550
LVSKMPGDWW QRRANVRAYL GFMWAHPGKQ LLFMGQEFAQ GAEWSEKQGP 600
EWWLLDEGYH SAGDHRGVQD LVRELNTRYT RTPALWQRDT DPAGFRWVSV 650
DAAEDNVFAF LRYGTDGTPL LAVSNFSPVV RHEYGLAVGD EAVAWQEVLN 700
TDAEEYGGGG VGNPDPVKPE DGSIRITLPP LATVWLMPYA L 741
Length:741
Mass (Da):82,776
Last modified:August 15, 2003 - v2
Checksum:i5FB7A44120677759
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti561 – 5611Q → H in CAA52109. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X73903 Genomic DNA. Translation: CAA52109.1.
AL939131 Genomic DNA. Translation: CAB92878.1.
PIRiS70078. S34218.
RefSeqiNP_631386.1. NC_003888.3.
WP_011031592.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB92878; CAB92878; CAB92878.
GeneIDi1102770.
KEGGisco:SCO7332.
PATRICi23744587. VBIStrCoe124346_7436.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X73903 Genomic DNA. Translation: CAA52109.1 .
AL939131 Genomic DNA. Translation: CAB92878.1 .
PIRi S70078. S34218.
RefSeqi NP_631386.1. NC_003888.3.
WP_011031592.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q59832.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO7332.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB92878 ; CAB92878 ; CAB92878 .
GeneIDi 1102770.
KEGGi sco:SCO7332.
PATRICi 23744587. VBIStrCoe124346_7436.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi HENIENP.
OrthoDBi EOG6JX7GT.
PhylomeDBi Q59832.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Tissue-specific glycogen branching isoenzymes in a multicellular prokaryote, Streptomyces coelicolor A3(2)."
    Bruton C.J., Plaskitt K.A., Chater K.F.
    Mol. Microbiol. 18:89-99(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: A3(2) / NRRL B-16638.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiGLGB2_STRCO
AccessioniPrimary (citable) accession number: Q59832
Secondary accession number(s): Q9KY06
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: August 15, 2003
Last modified: September 3, 2014
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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