Reviewed, UniProtKB/Swiss-Prot Q59714 (CATA_PSEPU)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:	katA
Synonyms:	catA

Organism

Pseudomonas putida

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	479 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Enzyme regulation	Activated by peroxide.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 479	479	Catalase		PRO_0000084995
Sites
	Active site	53	1	By similarity
	Active site	126	1	By similarity
	Metal binding	336	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q59714-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: EFE3CBDE67778571	FASTA	479	53,381
	10 20 30 40 50 60 MSKILTTASG APVADNQNSR SAGPRGPLLL DDFHLIEKLA HFNRENIPER RVHAKGSGAY 70 80 90 100 110 120 GTFTVTRDIT GYTSAKLFEQ VGKQTETFLR FSTVGGERGS ADTERDPRGF AVKFYTEEGN 130 140 150 160 170 180 WDIVGNNTPV FFIRDPLKFP DFIHTQKRHP QSNLKNAQIF WDSWSHSPEA LHQVTILFSD 190 200 210 220 230 240 RGIPDGYRHM HGFGSHTYSL INAQGERTWV KWHFKTQQGI KNLAPADAAR LAGTDPDYAQ 250 260 270 280 290 300 RDLFEAIERG DYPRWTVCIQ VMSEAEAASR DENPFDVTKT WSQKDYPLIE VGVLELNRNP 310 320 330 340 350 360 LNYFAEVEQA AFGPSNMVPG VGLSPDRMLQ GRVFAYADAH RYRVGTNHQQ LPVNAPRCPV 370 380 390 400 410 420 NSYQRDGSMA TGSYGSAPNY EPNSYAAAPK QSPRHAEPAL ALNGSADRYD HREDADYYSH 430 440 450 460 470 AGALFRLMSD EQKALLISNI AGTMAGVSEN VIQRQLQYFF KADPAYGEGI AKGLGINLA

References

[1]	"Identification of adjacent genes encoding the major catalase and a bacterioferritin from the plant-beneficial bacterium Pseudomonas putida." Kim Y.C., Miller C.D., Anderson A.J. Gene 199:219-224(1997) [PubMed: 9358059] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Corvallis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U63511 Genomic DNA. Translation: AAB88219.1.
3D structure databases
HSSP	HSSP built from PDB template 1M85 based on UniProtKB P42321.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.6. 403.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_PSEPU

Accession

Primary (citable) accession number: Q59714

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)