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Protein

Catalase

Gene

katA

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

Enzyme regulationi

Activated by peroxide.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei53 – 531PROSITE-ProRule annotation
Active sitei126 – 1261PROSITE-ProRule annotation
Metal bindingi336 – 3361Iron (heme axial ligand)By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase (EC:1.11.1.6)
Gene namesi
Name:katA
Synonyms:catA
OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifieri303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 479479CatalasePRO_0000084995Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_0481.

Structurei

3D structure databases

ProteinModelPortaliQ59714.
SMRiQ59714. Positions 2-479.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.Curated

Phylogenomic databases

eggNOGiENOG4105CH6. Bacteria.
COG0753. LUCA.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59714-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKILTTASG APVADNQNSR SAGPRGPLLL DDFHLIEKLA HFNRENIPER
60 70 80 90 100
RVHAKGSGAY GTFTVTRDIT GYTSAKLFEQ VGKQTETFLR FSTVGGERGS
110 120 130 140 150
ADTERDPRGF AVKFYTEEGN WDIVGNNTPV FFIRDPLKFP DFIHTQKRHP
160 170 180 190 200
QSNLKNAQIF WDSWSHSPEA LHQVTILFSD RGIPDGYRHM HGFGSHTYSL
210 220 230 240 250
INAQGERTWV KWHFKTQQGI KNLAPADAAR LAGTDPDYAQ RDLFEAIERG
260 270 280 290 300
DYPRWTVCIQ VMSEAEAASR DENPFDVTKT WSQKDYPLIE VGVLELNRNP
310 320 330 340 350
LNYFAEVEQA AFGPSNMVPG VGLSPDRMLQ GRVFAYADAH RYRVGTNHQQ
360 370 380 390 400
LPVNAPRCPV NSYQRDGSMA TGSYGSAPNY EPNSYAAAPK QSPRHAEPAL
410 420 430 440 450
ALNGSADRYD HREDADYYSH AGALFRLMSD EQKALLISNI AGTMAGVSEN
460 470
VIQRQLQYFF KADPAYGEGI AKGLGINLA
Length:479
Mass (Da):53,381
Last modified:November 1, 1996 - v1
Checksum:iEFE3CBDE67778571
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U63511 Genomic DNA. Translation: AAB88219.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U63511 Genomic DNA. Translation: AAB88219.1.

3D structure databases

ProteinModelPortaliQ59714.
SMRiQ59714. Positions 2-479.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_0481.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105CH6. Bacteria.
COG0753. LUCA.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of adjacent genes encoding the major catalase and a bacterioferritin from the plant-beneficial bacterium Pseudomonas putida."
    Kim Y.C., Miller C.D., Anderson A.J.
    Gene 199:219-224(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Corvallis.

Entry informationi

Entry nameiCATA_PSEPU
AccessioniPrimary (citable) accession number: Q59714
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: November 11, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.