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Q59649 (TRPF_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:PA3113
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [Reference proteome] [HAMAP]
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 211211N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154369

Sequences

Sequence LengthMass (Da)Tools
Q59649 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: CD88FDAF865D421B

FASTA21122,299
        10         20         30         40         50         60 
MPAVRIKICG ITRVEDALAA AAAGADAIGL VFYAKSPRAV DIHRAREIVR ALPPFVTSVG 

        70         80         90        100        110        120 
LFVNASRCEL GEILDAVPLD LLQFHGDERA EDCEGHRRPY LKALRMKPGD DIVGRAAAYP 

       130        140        150        160        170        180 
GAAGILLDTY VEGVPGGTGA AFDWSLVPTD LGKPLVLAGG LTPDNVGRAV EQVKPYAVDV 

       190        200        210 
SGGVEASKGI KDAARVRAFV DAVRSRRRDE T 

« Hide

References

« Hide 'large scale' references
[1]"The trpF nucleotide sequence and its promoter analysis in Pseudomonas aeruginosa."
Murata T.
Microbiol. Immunol. 40:107-114(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
[2]"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen."
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R. expand/collapse author list , Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.
Nature 406:959-964(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D83654 Genomic DNA. Translation: BAA12028.1.
AE004091 Genomic DNA. Translation: AAG06501.1.
PIRD83257.
RefSeqNP_251803.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ59649.
SMRQ59649. Positions 4-200.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208964.PA3113.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG06501; AAG06501; PA3113.
GeneID877681.
KEGGpae:PA3113.
PATRIC19840799. VBIPseAer58763_3265.

Organism-specific databases

PseudoCAPPA3113.

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.
OMAPDYAGFV.
OrthoDBEOG6N94DF.
PhylomeDBQ59649.

Enzyme and pathway databases

UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_PSEAE
AccessionPrimary (citable) accession number: Q59649
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways