Reviewed, UniProtKB/Swiss-Prot Q59602 (CATA_NEIGO)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:

katA

Organism

Neisseria gonorrhoeae

Taxonomic identifier

485 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Catalase		PRO_0000084991
Sites
	Active site	59	1	By similarity
	Active site	131	1	By similarity
	Metal binding	339	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q59602-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: CBF76FD8951B0D5F	FASTA	500	56,671
	10 20 30 40 50 60 MTTSKCPVTH LTMNNGAPVA DNQNSLTAGT RGPLLTQDLW LNEKLADFVR EVIPERRMHA 70 80 90 100 110 120 KGSGAFGTFT VTRDITKYTR AKIFSEVGKK TEMFGRLATV AGERGADAYT RVRGFALKFY 130 140 150 160 170 180 TEEGNWDVVG NNTPVFYPDL RKFPDLNKAV KRSAHQYSSA TNNWDFWALL PEALHQVTIV 190 200 210 220 230 240 MSDRGIPASY RHMHGFGSHT YSLWNEAGER FWVKFHFRSQ QGIKNLTNEE AAKIIADDRE 250 260 270 280 290 300 SHQRDLYEAI ERGEFPKWTM YIQVMPEADA AKVPYHPFDL TKVWPKKDYP LIEVAEFELN 310 320 330 340 350 360 RNPENFFADV EQSAFAPSNL VPGIGASPDK MLQARLFNYA DAQRYRLGVN FRQIPVNRPR 370 380 390 400 410 420 CPVHSNQRDG QGRATELRQP AHYEPNSFGQ WSQQPDFAEP PLKINGDAAH WDYRQDDDDY 430 440 450 460 470 480 FSQPRALFNL MNDAQKQALF DNTAAAMGDA PDFIKYRHIR NCYRCDPAYG EGGSKALGLT 490 500 VEEPQAARAT DPALGQGGLL

References

[1]	"Cloning and characterization of the catalase gene of Neisseria gonorrhoeae: use of the gonococcus as a host organism for recombinant DNA." Johnson S.R., Steiner B.M., Perkins G.H. Infect. Immun. 64:2627-2634(1996) [PubMed: 8698488] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U35457 Genomic DNA. Translation: AAB18144.1.
3D structure databases
HSSP	HSSP built from PDB template 1M85 based on UniProtKB P42321.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.6. 588.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_NEIGO

Accession

Primary (citable) accession number: Q59602

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)