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Protein

Catalase

Gene

katA

Organism
Neisseria gonorrhoeae
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei59 – 591PROSITE-ProRule annotation
Active sitei131 – 1311PROSITE-ProRule annotation
Metal bindingi339 – 3391Iron (heme axial ligand)By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase (EC:1.11.1.6)
Gene namesi
Name:katA
OrganismiNeisseria gonorrhoeae
Taxonomic identifieri485 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500CatalasePRO_0000084991Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ59602.
SMRiQ59602. Positions 11-483.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.Curated

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59602-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTSKCPVTH LTMNNGAPVA DNQNSLTAGT RGPLLTQDLW LNEKLADFVR
60 70 80 90 100
EVIPERRMHA KGSGAFGTFT VTRDITKYTR AKIFSEVGKK TEMFGRLATV
110 120 130 140 150
AGERGADAYT RVRGFALKFY TEEGNWDVVG NNTPVFYPDL RKFPDLNKAV
160 170 180 190 200
KRSAHQYSSA TNNWDFWALL PEALHQVTIV MSDRGIPASY RHMHGFGSHT
210 220 230 240 250
YSLWNEAGER FWVKFHFRSQ QGIKNLTNEE AAKIIADDRE SHQRDLYEAI
260 270 280 290 300
ERGEFPKWTM YIQVMPEADA AKVPYHPFDL TKVWPKKDYP LIEVAEFELN
310 320 330 340 350
RNPENFFADV EQSAFAPSNL VPGIGASPDK MLQARLFNYA DAQRYRLGVN
360 370 380 390 400
FRQIPVNRPR CPVHSNQRDG QGRATELRQP AHYEPNSFGQ WSQQPDFAEP
410 420 430 440 450
PLKINGDAAH WDYRQDDDDY FSQPRALFNL MNDAQKQALF DNTAAAMGDA
460 470 480 490 500
PDFIKYRHIR NCYRCDPAYG EGGSKALGLT VEEPQAARAT DPALGQGGLL
Length:500
Mass (Da):56,671
Last modified:November 1, 1996 - v1
Checksum:iCBF76FD8951B0D5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35457 Genomic DNA. Translation: AAB18144.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35457 Genomic DNA. Translation: AAB18144.1.

3D structure databases

ProteinModelPortaliQ59602.
SMRiQ59602. Positions 11-483.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCATA_NEIGO
AccessioniPrimary (citable) accession number: Q59602
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 14, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.