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Protein
Submitted name:

Tungsten formylmethanofuran dehydrogenase

Gene

fwdF

Organism
Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding

Protein family/group databases

TCDBi3.D.8.1.1. the na(+)- or h(+)-pumping formyl methanofuran dehydrogenase (fmf-dh) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Tungsten formylmethanofuran dehydrogenaseImported (EC:1.2.99.5Imported)
Gene namesi
Name:fwdFImported
OrganismiMethanothermobacter thermautotrophicus (Methanobacterium thermoformicicum)Imported
Taxonomic identifieri145262 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

Interactioni

Protein-protein interaction databases

STRINGi187420.MTH1554.

Structurei

3D structure databases

ProteinModelPortaliQ59575.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 51314Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini62 – 91304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini106 – 135304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini145 – 174304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini185 – 214304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini230 – 259304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini262 – 291304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini299 – 328304Fe-4S ferredoxin-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4102T9T. Archaea.
ENOG410ZN2K. LUCA.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR016459. Formylmethanofuran_DH_fsu.
[Graphical view]
PfamiPF00037. Fer4. 2 hits.
PF12838. Fer4_7. 3 hits.
[Graphical view]
PIRSFiPIRSF005658. FwdF. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 8 hits.
PS51379. 4FE4S_FER_2. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59575-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METTEVIEGK NITVERTGEE NRKLIFQDCL CAVCGLCGEI CPVSAIEVNP
60 70 80 90 100
TGAMVRTEQD ESKILIDENK CVLCGMCSSI CPFQALDLQI DGTSIKELAE
110 120 130 140 150
YPKILKSAEI DDETCIQCKA CETACPQDAI TITRELPERK DLITGEIEID
160 170 180 190 200
KDTCIYCGMC EEMCPVDAIE IEHQIPSSSS PTVATDINVD EDKCVHCGIC
210 220 230 240 250
KRICPVDAIM QVCRICPYGE YEIKVPEVTG TSYIDPELCV NCGWCQEICP
260 270 280 290 300
VDAATVTKPF EGELIIDQDT CQACETCVMA CPCNVLSFPK PEKSGEKPTK
310 320 330 340
LYKDERFCIY CGACERSCPV NAIEVKRSRI NTTPIKSKAW KNAFESLLK
Length:349
Mass (Da):38,578
Last modified:November 1, 1996 - v1
Checksum:i838AA10D876053FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87970 Genomic DNA. Translation: CAA61210.1.
PIRiS63542. S57453.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87970 Genomic DNA. Translation: CAA61210.1.
PIRiS63542. S57453.

3D structure databases

ProteinModelPortaliQ59575.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187420.MTH1554.

Protein family/group databases

TCDBi3.D.8.1.1. the na(+)- or h(+)-pumping formyl methanofuran dehydrogenase (fmf-dh) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4102T9T. Archaea.
ENOG410ZN2K. LUCA.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR016459. Formylmethanofuran_DH_fsu.
[Graphical view]
PfamiPF00037. Fer4. 2 hits.
PF12838. Fer4_7. 3 hits.
[Graphical view]
PIRSFiPIRSF005658. FwdF. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 8 hits.
PS51379. 4FE4S_FER_2. 8 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The tungsten formylmethanofuran dehydrogenase from Methanobacterium thermoautotrophicum contains sequence motifs characteristic for enzymes containing molybdopterin dinucleotide."
    Hochheimer A., Schmitz R.A., Thauer R.K., Hedderich R.
    Eur. J. Biochem. 234:910-920(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Marburg/DSM 2133Imported.

Entry informationi

Entry nameiQ59575_METTF
AccessioniPrimary (citable) accession number: Q59575
Secondary accession number(s): O08489
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.