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Protein

RNA polymerase sigma factor

Gene

ML1014

Organism
Mycobacterium leprae (strain TN)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciMLEP272631:G1GT5-1101-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Ordered Locus Names:ML1014Imported
OrganismiMycobacterium leprae (strain TN)Imported
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi

Organism-specific databases

LepromaiML1014

Interactioni

Protein-protein interaction databases

STRINGi272631.ML1014

Structurei

3D structure databases

ProteinModelPortaliQ59531
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 123RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini279 – 305RNA_pol_sigma70InterPro annotationAdd BLAST27

Sequence similaritiesi

Belongs to the sigma-70 factor family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DG1 Bacteria
COG0568 LUCA
HOGENOMiHOG000270273
KOiK03087
OMAiYQRWLAE
OrthoDBiPOG091H0012

Family and domain databases

Gene3Di1.10.10.10, 2 hits
InterProiView protein in InterPro
IPR014284 RNA_pol_sigma-70_dom
IPR000943 RNA_pol_sigma70
IPR009042 RNA_pol_sigma70_r1_2
IPR007627 RNA_pol_sigma70_r2
IPR007624 RNA_pol_sigma70_r3
IPR007630 RNA_pol_sigma70_r4
IPR013325 RNA_pol_sigma_r2
IPR013324 RNA_pol_sigma_r3/r4-like
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00140 Sigma70_r1_2, 1 hit
PF04542 Sigma70_r2, 1 hit
PF04539 Sigma70_r3, 1 hit
PF04545 Sigma70_r4, 1 hit
PRINTSiPR00046 SIGMA70FCT
SUPFAMiSSF88659 SSF88659, 2 hits
SSF88946 SSF88946, 1 hit
TIGRFAMsiTIGR02937 sigma70-ECF, 1 hit
PROSITEiView protein in PROSITE
PS00715 SIGMA70_1, 1 hit
PS00716 SIGMA70_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q59531-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEATTNRVD SDLDAQSPAA DLVRVYLNGI GKTALLNAAD EVELAKRIEA
60 70 80 90 100
GLYAEHLLQT RKRFGEGRKR ALAAVARDGA AARRHLLEAN LRLVVSLAKR
110 120 130 140 150
YTGRGMPLLD LIQEGNLGLI RAMEKFDYTK GFKFSTYATW WIRQAITRGM
160 170 180 190 200
ADQSRTIRLP VHLVEQVNKL ARIKREMHQN LGREATDEEL AAESGIPIEK
210 220 230 240 250
INDLLEHSRD PVSLDMPVGS EEEAPLGDFI EDAEAMSAEN AVIAELLHTD
260 270 280 290 300
IRSVLATLDE REHQVIRLRF GLDDGQPRTL DQIGKLFGLS RERVRQIERD
310
VMCKLRNGER ADRLRSYAS
Length:319
Mass (Da):35,847
Last modified:November 1, 1996 - v1
Checksum:iF76F45186D4BA477
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL583920 Genomic DNA Translation: CAC31395.1
PIRiH87035
RefSeqiNP_301750.1, NC_002677.1
WP_010908074.1, NC_002677.1

Genome annotation databases

EnsemblBacteriaiCAC31395; CAC31395; CAC31395
GeneIDi910072
KEGGimle:ML1014
PATRICifig|272631.5.peg.1844

Entry informationi

Entry nameiQ59531_MYCLE
AccessioniPrimary (citable) accession number: Q59531
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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