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Q59482 (DEOD_KLEPN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Synonyms:pnp
OrganismKlebsiella pneumoniae
Taxonomic identifier573 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_0000063139

Sequences

Sequence LengthMass (Da)Tools
Q59482 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: BC7514EDF5BB27F5

FASTA23926,196
        10         20         30         40         50         60 
MATPHINAEM GDFADVVLMP GDPLRANSIA ETFLEDAREV NNVRGMLGFT GTYKGRRKIS 

        70         80         90        100        110        120 
VMGHGMGIPS CSIYTKELIT DFGVKKIIRV GSCGAVREDV KLREVVIGHG ACTDSKVNRL 

       130        140        150        160        170        180 
RFKDHDFPAI ADFGMVRNAV DAKALGVEAR RSNIFSADLF YTPDPSMFDV MEKYGILGVE 

       190        200        210        220        230 
MEAAGIYGVA AEFGAKALTI CTVSDHIRTH EQTIAAERQT TFNDMIKIAL ESVLLRDKE 

« Hide

References

[1]"Molecular cloning and nucleotide sequence of purine nucleoside phosphorylase and uridine phosphorylase genes from Klebsiella sp."
Takehara M., Ling F., Izawa S., Inoue Y., Kimura A.
Biosci. Biotechnol. Biochem. 59:1987-1990(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LF1202.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X87881 Genomic DNA. Translation: CAA61136.1.

3D structure databases

ProteinModelPortalQ59482.
SMRQ59482. Positions 2-238.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ59482.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_KLEPN
AccessionPrimary (citable) accession number: Q59482
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families