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Q59477 (DHAT_KLEPN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,3-propanediol dehydrogenase

EC=1.1.1.202
Alternative name(s):
1,3-propanediol oxidoreductase
3-hydroxypropionaldehyde reductase
Gene names
Name:dhaT
OrganismKlebsiella pneumoniae
Taxonomic identifier573 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH.

Cofactor

Iron By similarity.

Subunit structure

Homooctamer By similarity.

Sequence similarities

Belongs to the iron-containing alcohol dehydrogenase family.

Ontologies

Keywords
   LigandIron
NAD
   Molecular functionOxidoreductase
   Technical term3D-structure
Gene Ontology (GO)
   Molecular_function1,3-propanediol dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3873871,3-propanediol dehydrogenase
PRO_0000087842

Sequences

Sequence LengthMass (Da)Tools
Q59477 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 37E7BD4CDF2EC409

FASTA38741,466
        10         20         30         40         50         60 
MSYRMFDYLV PNVNFFGPNA ISVVGERCQL LGGKKALLVT DKGLRAIKDG AVDKTLHYLR 

        70         80         90        100        110        120 
EAGIEVAIFD GVEPNPKDTN VRDGLAVFRR EQCDIIVTVG GGSPHDCGKG IGIAATHEGD 

       130        140        150        160        170        180 
LYQYAGIETL TNPLPPIVAV NTTAGTASEV TRHCVLTNTE TKVKFVIVSW RNLPSVSIND 

       190        200        210        220        230        240 
PLLMIGKPAA LTAATGMDAL THAVEAYISK DANPVTDAAA MQAIRLIARN LRQAVALGSN 

       250        260        270        280        290        300 
LQARENMAYA SLLAGMAFNN ANLGYVHAMA HQLGGLYDMP HGVANAVLLP HVARYNLIAN 

       310        320        330        340        350        360 
PEKFADIAEL MGENITGLST LDAAEKAIAA ITRLSMDIGI PQHLRDLGVK EADFPYMAEM 

       370        380 
ALKDGNAFSN PRKGNEQEIA AIFRQAF 

« Hide

References

[1]Skraly F.A., Willard B.L., Cameron D.C.
Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 25955.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U30903 Genomic DNA. Translation: AAA74260.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3BFJX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T1-387[»]
ProteinModelPortalQ59477.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycRETL1328306-WGS:GSTH-2932-MONOMER.
BRENDA1.1.1.31. 5163.

Family and domain databases

InterProIPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
[Graphical view]
PfamPF00465. Fe-ADH. 1 hit.
[Graphical view]
PROSITEPS00913. ADH_IRON_1. 1 hit.
PS00060. ADH_IRON_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ59477.

Entry information

Entry nameDHAT_KLEPN
AccessionPrimary (citable) accession number: Q59477
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references