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Protein

1,3-propanediol dehydrogenase

Gene

dhaT

Organism
Klebsiella pneumoniae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH.

Cofactori

Fe cationBy similarity

GO - Molecular functioni

  1. 1,3-propanediol dehydrogenase activity Source: UniProtKB-EC
  2. metal ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Iron, NAD

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-2932-MONOMER.
BRENDAi1.1.1.31. 5163.

Names & Taxonomyi

Protein namesi
Recommended name:
1,3-propanediol dehydrogenase (EC:1.1.1.202)
Alternative name(s):
1,3-propanediol oxidoreductase
3-hydroxypropionaldehyde reductase
Gene namesi
Name:dhaT
OrganismiKlebsiella pneumoniae
Taxonomic identifieri573 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3873871,3-propanediol dehydrogenasePRO_0000087842Add
BLAST

Interactioni

Subunit structurei

Homooctamer.By similarity

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BFJX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T1-387[»]
ProteinModelPortaliQ59477.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ59477.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]
PROSITEiPS00913. ADH_IRON_1. 1 hit.
PS00060. ADH_IRON_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59477-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYRMFDYLV PNVNFFGPNA ISVVGERCQL LGGKKALLVT DKGLRAIKDG
60 70 80 90 100
AVDKTLHYLR EAGIEVAIFD GVEPNPKDTN VRDGLAVFRR EQCDIIVTVG
110 120 130 140 150
GGSPHDCGKG IGIAATHEGD LYQYAGIETL TNPLPPIVAV NTTAGTASEV
160 170 180 190 200
TRHCVLTNTE TKVKFVIVSW RNLPSVSIND PLLMIGKPAA LTAATGMDAL
210 220 230 240 250
THAVEAYISK DANPVTDAAA MQAIRLIARN LRQAVALGSN LQARENMAYA
260 270 280 290 300
SLLAGMAFNN ANLGYVHAMA HQLGGLYDMP HGVANAVLLP HVARYNLIAN
310 320 330 340 350
PEKFADIAEL MGENITGLST LDAAEKAIAA ITRLSMDIGI PQHLRDLGVK
360 370 380
EADFPYMAEM ALKDGNAFSN PRKGNEQEIA AIFRQAF
Length:387
Mass (Da):41,466
Last modified:November 1, 1996 - v1
Checksum:i37E7BD4CDF2EC409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30903 Genomic DNA. Translation: AAA74260.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30903 Genomic DNA. Translation: AAA74260.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BFJX-ray2.70A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T1-387[»]
ProteinModelPortaliQ59477.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-2932-MONOMER.
BRENDAi1.1.1.31. 5163.

Miscellaneous databases

EvolutionaryTraceiQ59477.

Family and domain databases

InterProiIPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]
PROSITEiPS00913. ADH_IRON_1. 1 hit.
PS00060. ADH_IRON_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Skraly F.A., Willard B.L., Cameron D.C.
    Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 25955.

Entry informationi

Entry nameiDHAT_KLEPN
AccessioniPrimary (citable) accession number: Q59477
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.