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Q59463 (Q59463_HYPME) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Hydroxypyruvate reductase EMBL BAA06662.1
EC=1.1.1.81 EMBL BAA06662.1
OrganismHyphomicrobium methylovorum EMBL BAA06662.1
Taxonomic identifier84 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Hyphomicrobiaceae › Hyphomicrobium

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
   LigandPyruvate EMBL BAA06662.1
   Molecular functionOxidoreductase EMBL BAA06662.1
Gene Ontology (GO)
   Molecular_functionNAD binding

Inferred from electronic annotation. Source: InterPro

hydroxypyruvate reductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q59463 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 05B6239F49D7BC26

FASTA32235,727
        10         20         30         40         50         60 
MSKKKILITW PLPEAAMARA RESYDVIAHG DDPKITIDEM IETAKSVDAL LITLNEKCRK 

        70         80         90        100        110        120 
EVIDRIPENI KCISTYSIGF DHIDLDACKA RGIKVGNAPH GVTVATAEIA MLLLLGSARR 

       130        140        150        160        170        180 
AGEGEKMIRT RSWPGWQPLQ LVGQRLDNKT LGIYGFGKIG QALAQRARGF DMNVHYYDIY 

       190        200        210        220        230        240 
RAKPEVEAKY NATYHDSLDS LLKVSQFFSI NAPSTPETRY FFNKETIEKL PQGAIVVNTA 

       250        260        270        280        290        300 
RGDLVKDDDV IAALKSGRLA YAGFDVFAGE PNINEGYYDL PNTFLFPHLG SAAIEARNQM 

       310        320 
GFEALDNIDA FFAGKDMPFK LA

« Hide

References

[1]"Cloning and expression of the gene for hydroxypyruvate reductase (D-glycerate dehydrogenase from an obligate methylotroph Hyphomicrobium methylovorum GM2."
Yoshida T., Yamaguchi K., Hagishita T., Mitsunaga T., Miyata A., Tanabe T., Toh H., Ohshiro T., Shimao M., Izumi Y.
Eur. J. Biochem. 223:727-732(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: GM2 EMBL BAA06662.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D31857 Genomic DNA. Translation: BAA06662.1.
PIRS48189.

3D structure databases

HSSPHSSP built from PDB template 1GDH based on UniProtKB P36234.
ProteinModelPortalQ59463.
SMRQ59463. Positions 3-322.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.720. 2 hits.
InterProIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_2_OHA_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ59463_HYPME
AccessionPrimary (citable) accession number: Q59463
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info