Reviewed, UniProtKB/Swiss-Prot Q59437 (BGLA_ENTAG)

Names and origin

Protein names

Recommended name:
    Beta-glucosidase A
    EC=3.2.1.21
Alternative name(s):
    Gentiobiase
    Beta-D-glucoside glucohydrolase

Gene names

Name:

bglA

Organism

Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans)

Taxonomic identifier

549 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pantoea

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.
Sequence similarities	Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cellulose degradation Polysaccharide degradation
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	beta-glucosidase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 480	480	Beta-glucosidase A		PRO_0000063877
Sites
	Active site	177	1	Proton donor Potential
	Active site	378	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q59437-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 60493E7CDD69C403	FASTA	480	53,889
	10 20 30 40 50 60 MKNGMLALGM TAADVPDNFL WGAASAAYQV EGATNKDGKG RSVWDYYLDE KHLAGPGISG 70 80 90 100 110 120 ALRLTFTDRD QYLKDIQLFK ELGLNSYRFS HRLDTYYPDG QGPVNLRAVA HYRQFITDLE 130 140 150 160 170 180 AAGIKPLVTL YHWDMPESLS AAGGWENRES VEWFQRYAEV IFANFSDQVD QFVLINEPTV 190 200 210 220 230 240 EVATKIMAEK RLKGEELTLP PIVPAGSYLE TSLKSYNHIL LASAAAAESF KVKGYKGRLG 250 260 270 280 290 300 IALPFFPVLT TENASDEDKA DARLVDGILN RWFLDAMYKG NYPADVLKLA ADRHLNIDVQ 310 320 330 340 350 360 PGDAERIHDA GLGFLGINYY APFFIRHQKN ASEVYSPEII FPKNEKLAFN GAVRPDQFSA 370 380 390 400 410 420 LLERVRDEYG NPPVIITENG AGFEGEDQLT NGKVNDVNRC LYLVDHIHAM RESIARGANV 430 440 450 460 470 480 QGYYVWSSHD NLEWLSGYKS RFGMIYVDYD TQKRTPKLSA EIYGKIIRGE NISDVDCKSD

References

[1]

"Cloning and nucleotide sequence of the bglA gene from Erwinia herbicola and expression of beta-glucosidase activity in Escherichia coli." Marri L., Valentini S., Venditti D. FEMS Microbiol. Lett. 128:135-138(1995) [PubMed: 7750731] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: WD4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X79911 Genomic DNA. Translation: CAA56282.1.
PIR	S49182.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH1. Glycoside Hydrolase Family 1.
Enzyme and pathway databases
BRENDA	3.2.1.21. 3054.
Family and domain databases
InterPro	IPR001360. Glyco_hydro_1. IPR018120. Glyco_hydro_1_AS. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
PANTHER	PTHR10353. Glyco_hydro_1. 1 hit.
Pfam	PF00232. Glyco_hydro_1. 1 hit. [Graphical view]
PRINTS	PR00131. GLHYDRLASE1.
PROSITE	PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit. PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BGLA_ENTAG

Accession

Primary (citable) accession number: Q59437

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 24, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)