ID   ACKA_CLOTS              Reviewed;         400 AA.
AC   Q59331; O65981;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 50.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA;
OS   Clostridium thermosaccharolyticum (Thermoanaerobacterium
OS   thermosaccharolyticum).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacterales Family III. Incertae Sedis;
OC   Thermoanaerobacterium.
OX   NCBI_TaxID=1517;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 7956 / DSM 571 / LMG 2811 / NCA 3814 / NCIB 9385;
RA   Joerges A., Bronnenmeier K., Lottspeich F., Staudenbauer W.L.;
RL   Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 7956 / DSM 571 / LMG 2811 / NCA 3814 / NCIB 9385;
RA   van Rinsum A.;
RL   Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the activation of acetate to acetyl CoA and
CC       the secretion of acetate (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the acetokinase family.
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DR   EMBL; Z71384; CAA95986.1; -; Genomic_DNA.
DR   EMBL; AJ004870; CAA06175.1; -; Genomic_DNA.
DR   HSSP; P38502; 1G99.
DR   BRENDA; 2.7.2.1; 486.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:HAMAP.
DR   HAMAP; MF_00020; -; 1.
DR   InterPro; IPR000890; Acetate_kin.
DR   InterPro; IPR004372; AckA.
DR   PANTHER; PTHR21060; Acetate_kin; 1.
DR   PANTHER; PTHR21060:SF11; AckA; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    400       Acetate kinase.
FT                                /FTId=PRO_0000107550.
FT   CONFLICT    134    134       T -> K (in Ref. 2; CAA06175).
SQ   SEQUENCE   400 AA;  43820 MW;  7D18E412CB491BB8 CRC64;
     MKILVINCGS SSLKYQLIES KDGNVLAKGL AERIGINDSL LTHNANGEKI KIKKDMKDHK
     DAIKLVLDAL VNSDYGVIKD MSEIDAVGHR VVHGGEYFTS SVLITDDVLK AITDCIELAP
     LHNPANIEGI KACTQIMPDV PMVAVFDTAF HQTMPDYAYL YPIPYEYYTK YKIRKYGFHG
     TSHKYVSQRA AEILNKPIES LKIITCHLGN GSSIAAVKNG KSIDTSMGFT PLEGLAMGTR
     SGSIDPSIIS YLMEKENISA EEVVNILNKK SGVYGISGIS SDFRDLEDAA FKNGDKRAQL
     ALNVFAYRVK KTIGSYAAAM GGVDVIVFTA GIGENGPEIR EFILDGLEFL GFKLDKEKNK
     VRGEEAIIST ADSKVNVMVV PTNEEYMIAK DTEKIVESLK
//