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Q59330 (PTAS_THETC) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Synonyms:ptaA
Ordered Locus Names:Tthe_1502
OrganismThermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum) [Complete proteome] [HAMAP]
Taxonomic identifier580327 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisThermoanaerobacterium

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 328328Phosphate acetyltransferase
PRO_0000179127

Experimental info

Sequence conflict31 – 322AA → GP in CAA06174. Ref.2
Sequence conflict911I → L in CAA95985. Ref.1
Sequence conflict113 – 1175EGYAD → RRLCS in CAA95985. Ref.1
Sequence conflict1251H → D in CAA95985. Ref.1
Sequence conflict1371I → N in CAA95985. Ref.1
Sequence conflict247 – 2482AL → DV in CAA95985. Ref.1
Sequence conflict247 – 2482AL → DV in CAA06174. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q59330 [UniParc].

Last modified November 30, 2010. Version 2.
Checksum: 11C4C57B4DA39D17

FASTA32834,945
        10         20         30         40         50         60 
MSIIQSIIEK AKSNKKKIVL PEGAEPRTLK AADIVLKEGI ADLVLLGNAD EIRNAAEGLD 

        70         80         90        100        110        120 
ISKAEIIDPL KSEKFDKYAT DFYELRKNKG ITLEKAKETI KDNIYFGCMM VKEGYADGLV 

       130        140        150        160        170        180 
SGAIHATADL LRPAFQIVKT APGAKIVSSF FIMEVPNCEF GENGVFLFAD CAVNPSPNAE 

       190        200        210        220        230        240 
ELASIAVQSA NTAKTLLGME PRVAMLSFST KGSASHELVD KVRTATEIAK NLIPDVAIDG 

       250        260        270        280        290        300 
ELQLDAALVK EVAELKAPGS PVAGRANVLI FPDLQAGNIG YKLVQRLAKA NAIGPITQGM 

       310        320 
GAPVNDLSRG CSYKDIVDVI ATTAVQAQ 

« Hide

References

« Hide 'large scale' references
[1]Joerges A., Bronnenmeier K., Lottspeich F., Staudenbauer W.L.
Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.
[2]van Rinsum A.
Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.
[3]"Complete sequence of Thermoanaerobacterium thermosaccharolyticum DSM 571."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Hemme C.L., Woyke T.
Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z71384 Genomic DNA. Translation: CAA95985.1.
AJ004870 Genomic DNA. Translation: CAA06174.1.
CP002171 Genomic DNA. Translation: ADL69012.1.
RefSeqYP_003852096.1. NC_014410.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL69012; ADL69012; Tthe_1502.
GeneID9707058.
KEGGttm:Tthe_1502.
PATRIC42452351. VBITheThe89703_1522.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000053796.
KOK00625.

Enzyme and pathway databases

BioCycTTHE580327:GHGH-1545-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

InterProIPR012147. P_Ac_Bu_trans.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTAS_THETC
AccessionPrimary (citable) accession number: Q59330
Secondary accession number(s): D9TNN7, O65980
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 30, 2010
Last modified: October 16, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways