Q59330 (PTAS_THETC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Synonyms:	ptaA
Ordered Locus Names:	Tthe_1502

Organism

Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum) [Complete proteome] [HAMAP]

Taxonomic identifier

580327 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Thermoanaerobacterium

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Phosphate acetyltransferase		PRO_0000179127
Experimental info
	Sequence conflict	31 – 32	2	AA → GP in CAA06174. Ref.2
	Sequence conflict	91	1	I → L in CAA95985. Ref.1
	Sequence conflict	113 – 117	5	EGYAD → RRLCS in CAA95985. Ref.1
	Sequence conflict	125	1	H → D in CAA95985. Ref.1
	Sequence conflict	137	1	I → N in CAA95985. Ref.1
	Sequence conflict	247 – 248	2	AL → DV in CAA95985. Ref.1
	Sequence conflict	247 – 248	2	AL → DV in CAA06174. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q59330 [UniParc]. Last modified November 30, 2010. Version 2. Checksum: 11C4C57B4DA39D17	FASTA	328	34,945
	10 20 30 40 50 60 MSIIQSIIEK AKSNKKKIVL PEGAEPRTLK AADIVLKEGI ADLVLLGNAD EIRNAAEGLD 70 80 90 100 110 120 ISKAEIIDPL KSEKFDKYAT DFYELRKNKG ITLEKAKETI KDNIYFGCMM VKEGYADGLV 130 140 150 160 170 180 SGAIHATADL LRPAFQIVKT APGAKIVSSF FIMEVPNCEF GENGVFLFAD CAVNPSPNAE 190 200 210 220 230 240 ELASIAVQSA NTAKTLLGME PRVAMLSFST KGSASHELVD KVRTATEIAK NLIPDVAIDG 250 260 270 280 290 300 ELQLDAALVK EVAELKAPGS PVAGRANVLI FPDLQAGNIG YKLVQRLAKA NAIGPITQGM 310 320 GAPVNDLSRG CSYKDIVDVI ATTAVQAQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Joerges A., Bronnenmeier K., Lottspeich F., Staudenbauer W.L. Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.
[2]	van Rinsum A. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.
[3]	"Complete sequence of Thermoanaerobacterium thermosaccharolyticum DSM 571." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Hemme C.L., Woyke T. Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z71384 Genomic DNA. Translation: CAA95985.1. AJ004870 Genomic DNA. Translation: CAA06174.1. CP002171 Genomic DNA. Translation: ADL69012.1.
RefSeq	YP_003852096.1. NC_014410.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9707058.
GenomeReviews	Gene locus Tthe_1502 in contig CP002171_GR.
KEGG	ttm:Tthe_1502.
PATRIC	42452351. VBITheThe89703_1522.
Organism-specific databases
CMR	Search...
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K00625.
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTAS_THETC

Accession

Primary (citable) accession number: Q59330
Secondary accession number(s): D9TNN7, O65980

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 30, 2010
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program