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Protein

RNA polymerase sigma factor SigA

Gene

sigA

Organism
Chlamydophila psittaci (Chlamydia psittaci)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.SAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi515 – 534H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, Sigma factorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factor SigAUniRule annotation
Gene namesi
Name:sigAUniRule annotationImported
OrganismiChlamydophila psittaci (Chlamydia psittaci)Imported
Taxonomic identifieri83554 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Interacts transiently with the RNA polymerase catalytic core.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ59302.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini345 – 358RNA_pol_sigma70InterPro annotationAdd BLAST14
Domaini514 – 540RNA_pol_sigma70InterPro annotationAdd BLAST27

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni321 – 391Sigma-70 factor domain-2UniRule annotationAdd BLAST71
Regioni400 – 476Sigma-70 factor domain-3UniRule annotationAdd BLAST77
Regioni489 – 542Sigma-70 factor domain-4UniRule annotationAdd BLAST54

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi345 – 348Interaction with polymerase core subunit RpoCUniRule annotation4

Sequence similaritiesi

Belongs to the sigma-70 factor family. RpoD/SigA subfamily.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105DG1. Bacteria.
COG0568. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_00963. Sigma70_RpoD_SigA. 1 hit.
InterProiView protein in InterPro
IPR014284. RNA_pol_sigma-70_dom.
IPR000943. RNA_pol_sigma70.
IPR009042. RNA_pol_sigma70_r1_2.
IPR007627. RNA_pol_sigma70_r2.
IPR007624. RNA_pol_sigma70_r3.
IPR007630. RNA_pol_sigma70_r4.
IPR007127. RNA_pol_sigma_70_r1_1.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR012760. RNA_pol_sigma_RpoD_C.
IPR028630. Sigma70_RpoD.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF03979. Sigma70_r1_1. 1 hit.
PF00140. Sigma70_r1_2. 1 hit.
PF04542. Sigma70_r2. 1 hit.
PF04539. Sigma70_r3. 1 hit.
PF04545. Sigma70_r4. 1 hit.
PRINTSiPR00046. SIGMA70FCT.
SUPFAMiSSF88659. SSF88659. 2 hits.
SSF88946. SSF88946. 2 hits.
TIGRFAMsiTIGR02393. RpoD_Cterm. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiView protein in PROSITE
PS00715. SIGMA70_1. 1 hit.
PS00716. SIGMA70_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59302-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLMNTQNGQA MEAAHEEEAQ KKLEELVSLA KDQGFITYEE INEILPMSFD
60 70 80 90 100
TPEQIDQVLI FLTGMDIQVL NQADVERQKE RKKEAKELEG LAKRTEGTPD
110 120 130 140 150
DPVRMYLKEM GTVPLLTREE EVEISKRIEK AQVQIERIIL RFRYSSKEAI
160 170 180 190 200
SIAQYLINGK ERFDKIISEK EVEDKAHFLK LLPKLISLLK EEDAYLESLL
210 220 230 240 250
FRLKQNNLSK EETAKLNDDL EKCRIRTQAY LRCFHCRHNV TEDFGEVVFK
260 270 280 290 300
AYDSFLQLEQ QINDLKVRAE RNKFAAAKLD AAKRRLYKRE VAAGRTLEEF
310 320 330 340 350
KKDVRMLQRW MDKSQEAKKE MVESNLRLVI SIAKKYTNRG LSFLDLIQEG
360 370 380 390 400
NMGLMKAVEK FEYRRGYKFS TYATWWIRQA VTRAIADQAR TIRIPVHMIE
410 420 430 440 450
TINKVLRGAK KLMMETGKEP TPEELAEELG LTPDRVREIY KIAQHPISLQ
460 470 480 490 500
AEVGEGGESS FGDFLEDTGV ESPAEATGYS MLKDKMKEVL KTLTDRERFV
510 520 530 540 550
LIHRFGLLDG KPKTLEEVGS AFNVTRERIR QIEAKALRKM RHPIRSKQLR
560 570
AFLDLLEEEK ITGKAKNIKG K
Length:571
Mass (Da):66,246
Last modified:November 1, 1996 - v1
Checksum:i5C89C2E5F7CA40EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U04442 Genomic DNA. Translation: AAA50747.1.
PIRiI40872.

Similar proteinsi

Entry informationi

Entry nameiQ59302_CHLPS
AccessioniPrimary (citable) accession number: Q59302
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)