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Reviewed, UniProtKB/Swiss-Prot Q59296 (CATA_CAMJE)

Last modified January 19, 2010. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Catalase
    EC=1.11.1.6
Gene names
Name: katA
Ordered Locus Names: Cj1385
OrganismCampylobacter jejuni [Complete proteome] [HAMAP]
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length507 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Sequence similarities

Belongs to the catalase family.

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

fliYQ0PC741EBI-1195173,EBI-1191111

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 507507Catalase
PRO_0000084983

Sites

Active site521 By similarity
Active site1241 By similarity
Metal binding3341Iron (heme axial ligand) By similarity

Experimental info

Sequence conflict231T → A in CAL35497. Ref.2
Sequence conflict821I → V in CAL35497. Ref.2
Sequence conflict1771R → S in CAL35497. Ref.2
Sequence conflict2831L → F in CAL35497. Ref.2
Sequence conflict4401T → A in CAL35497. Ref.2
Sequence conflict4551E → K in CAL35497. Ref.2
Sequence conflict472 – 50736FPIVS…YEPEA → LEK in CAL35497. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q59296-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B1320894668E867E

FASTA50758,416
        10         20         30         40         50         60 
MKKLTNDFGN IIADNQNSLS AGTKGPLLMQ DYLLLEKLAH QNRERIPERT VHAKGSGAYG 

        70         80         90        100        110        120 
EIKITADLSA YTKAKIFQKG EITPLFLRFS TVAGEAGAAD AERDVRGFAI KFYTKEGNWD 

       130        140        150        160        170        180 
LVGNNTPTFF IRDAYKFPDF IHTQKRDPRT HLRSNNAAWD FWSLCPESLH QVTILMRDRG 

       190        200        210        220        230        240 
IPASYRHMHG FGSHTYSFIN DKNERFWVKF HFKTQQGIKN LTNQEAAELI AKDRESHQRD 

       250        260        270        280        290        300 
LYNAIENKDF PKWKVQVQIL AEKDIEKLGF NPFDLTKIWP HSLVPLMDIG EMILNKNPQN 

       310        320        330        340        350        360 
YFNEVEQAAF SPSNIVPGIG FSPDKMLQAR IFSYPDAQRY RIGTNYHLLP VNRAKSEVNT 

       370        380        390        400        410        420 
YNVAGAMNFD SYKNDAAYYE PNSYDNSPKE DKSYLEPDLV LEGVAQRYAP LDNDFYTQPR 

       430        440        450        460        470        480 
ALFNLMNDDQ KTQLFHNIAT SMEGVDEKII TRALEHFEKI SPDYAKGIKK AFPIVSRIRA 

       490        500 
WRNHGHRCFL CEIVIRSQFH TTYEPEA 

« Hide

References

« Hide 'large scale' references
[1]"Molecular characterization of katA from Campylobacter jejuni and generation of a catalase-deficient mutant of Campylobacter coli by interspecific allelic exchange."
Grant K.A., Park S.F.
Microbiology 141:1369-1376(1995) [PubMed: 7670638] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 33560 / CIP 702 / DSM 4688 / NCTC 11351.
[2]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed: 10688204] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X85130 Genomic DNA. Translation: CAA59444.1.
AL111168 Genomic DNA. Translation: CAL35497.1.
PIRF81283.
I40767.
RefSeqYP_002344773.1.

3D structure databases

SMRQ59296. Positions 2-474.
ModBaseSearch...

Protein-protein interaction databases

IntActQ59296. 38 interactions.

Protein family/group databases

PeroxiBase5383. CjejKat01.

Genome annotation databases

GeneID905678.
GenomeReviewsGene locus Cj1385 in contig AL111168_GR.
KEGGcje:Cj1385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG339355.

Enzyme and pathway databases

BioCycCJEJ192222:CJ1385-MONOMER.
BRENDA1.11.1.6. 255835.

Family and domain databases

InterProIPR002226. Catalase.
IPR020835. Catalase-like_haem-dep.
IPR010582. Catalase-rel_immune_responsive.
IPR011614. Catalase_N.
IPR018028. Catalase_rel_subgroup.
[Graphical view]
Gene3DG3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHERPTHR11465. Catalase. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PRINTSPR00067. CATALASE.
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. False negative.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA_CAMJE
AccessionPrimary (citable) accession number: Q59296
Secondary accession number(s): Q0P8M4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: January 19, 2010
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents