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Q59198

- CISY_BARDO

UniProt

Q59198 - CISY_BARDO

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Protein

Citrate synthase

Gene

gltA

Organism
Bartonella doshiae
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei249 – 2491PROSITE-ProRule annotation
Active sitei307 – 3071PROSITE-ProRule annotation

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase (EC:2.3.3.16)
Gene namesi
Name:gltA
OrganismiBartonella doshiae
Taxonomic identifieri33044 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›320›320Citrate synthasePRO_0000169932Add
BLAST

Proteomic databases

PRIDEiQ59198.

Structurei

3D structure databases

ProteinModelPortaliQ59198.
SMRiQ59198. Positions 1-320.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.Curated

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59198 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TYIDGDKGIL LYRGYPIEQL AEKGDFLESC YLLLYGELPT QQEKNDFDRR
60 70 80 90 100
IMQHTMVHEQ FSRFFQGFRR DSHPMAVMVA CLGAMSAFYH DSIDITDPQQ
110 120 130 140 150
RMIASIRLIS KVPTLAAMAY KYSIGQAFVY PHNSLSYAAN FLRMCFAVPC
160 170 180 190 200
EEYQVNPVLT RAMDRIFILH ADHEQNASTS TVRLAGSSGA NPFACIAAGV
210 220 230 240 250
ACLWGPAHGG ANEACLKMLK EIGSVKKIPE FIARAKDKND PFRLMGFGHR
260 270 280 290 300
VYKNYDPRAK IMQKTCHEVL KELNRQDDPL LDIAIELEHI ALNDEYFIEK
310 320
KLYPNVDFYS GITLKALGFP
Length:320
Mass (Da):36,285
Last modified:November 1, 1997 - v1
Checksum:i22F7BA8B2452297C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei320 – 3201

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z70017 Genomic DNA. Translation: CAA93839.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z70017 Genomic DNA. Translation: CAA93839.1 .

3D structure databases

ProteinModelPortali Q59198.
SMRi Q59198. Positions 1-320.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q59198.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .

Family and domain databases

Gene3Di 1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001369. Citrate_synth. 1 hit.
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparison of partial citrate synthase gene (gltA) sequences for phylogenetic analysis of Bartonella species."
    Birtles R.J., Raoult D.
    Int. J. Syst. Bacteriol. 46:891-897(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: R18.

Entry informationi

Entry nameiCISY_BARDO
AccessioniPrimary (citable) accession number: Q59198
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 1, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3