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Q59198 (CISY_BARDO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Citrate synthase

EC=2.3.3.16
Gene names
Name:gltA
OrganismBartonella doshiae
Taxonomic identifier33044 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length320 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.

Miscellaneous

Citrate synthase is found in nearly all cells capable of oxidative metabolism.

Sequence similarities

Belongs to the citrate synthase family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processcellular carbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncitrate (Si)-synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›320›320Citrate synthase
PRO_0000169932

Sites

Active site2491 By similarity
Active site3071 By similarity

Experimental info

Non-terminal residue11
Non-terminal residue3201

Sequences

Sequence LengthMass (Da)Tools
Q59198 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 22F7BA8B2452297C

FASTA32036,285
        10         20         30         40         50         60 
TYIDGDKGIL LYRGYPIEQL AEKGDFLESC YLLLYGELPT QQEKNDFDRR IMQHTMVHEQ 

        70         80         90        100        110        120 
FSRFFQGFRR DSHPMAVMVA CLGAMSAFYH DSIDITDPQQ RMIASIRLIS KVPTLAAMAY 

       130        140        150        160        170        180 
KYSIGQAFVY PHNSLSYAAN FLRMCFAVPC EEYQVNPVLT RAMDRIFILH ADHEQNASTS 

       190        200        210        220        230        240 
TVRLAGSSGA NPFACIAAGV ACLWGPAHGG ANEACLKMLK EIGSVKKIPE FIARAKDKND 

       250        260        270        280        290        300 
PFRLMGFGHR VYKNYDPRAK IMQKTCHEVL KELNRQDDPL LDIAIELEHI ALNDEYFIEK 

       310        320 
KLYPNVDFYS GITLKALGFP 

« Hide

References

[1]"Comparison of partial citrate synthase gene (gltA) sequences for phylogenetic analysis of Bartonella species."
Birtles R.J., Raoult D.
Int. J. Syst. Bacteriol. 46:891-897(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: R18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z70017 Genomic DNA. Translation: CAA93839.1.

3D structure databases

ProteinModelPortalQ59198.
SMRQ59198. Positions 1-320.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ59198.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00223; UER00717.

Family and domain databases

Gene3D1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-II.
[Graphical view]
PANTHERPTHR11739. PTHR11739. 1 hit.
PfamPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001369. Citrate_synth. 1 hit.
PRINTSPR00143. CITRTSNTHASE.
SUPFAMSSF48256. SSF48256. 1 hit.
TIGRFAMsTIGR01798. cit_synth_I. 1 hit.
PROSITEPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCISY_BARDO
AccessionPrimary (citable) accession number: Q59198
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways