SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q59181

- PGK_BORBU

UniProt

Q59181 - PGK_BORBU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoglycerate kinase

Gene
pgk, BB_0056
Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371Substrate By similarity
Binding sitei119 – 1191Substrate By similarity
Binding sitei152 – 1521Substrate By similarity
Binding sitei202 – 2021ATP By similarity
Binding sitei293 – 2931ATP; via carbonyl oxygen By similarity
Binding sitei324 – 3241ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi350 – 3534ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBBUR224326:G9SO-55-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:BB_0056
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001807: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Phosphoglycerate kinaseUniRule annotationPRO_0000145911Add
BLAST

Proteomic databases

PRIDEiQ59181.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi224326.BB0056.

Structurei

3D structure databases

ProteinModelPortaliQ59181.
SMRiQ59181. Positions 1-393.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 243Substrate binding By similarity
Regioni60 – 634Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59181-1 [UniParc]FASTAAdd to Basket

« Hide

MSIKTVKDFS SFAGKRALVR CDFNVPLKEG SISDDTRIRA ALSTIEYLKE    50
RGARIVLVSH LGRPDGKKNP KYSLKPVANR LSELLGQDVK MLSDCIGSEV 100
VNSTLQMKDG DVVLLENVRF YAEEEKNDKN FAKKLSENGD VFVNDAFGAA 150
HRAHASTVGV ADYLPSVGGF LMEKEDKFLG GILKNPERPF VSIIGGSKVS 200
SKIAVLESLL SKSNVVVIGG GMAYTFLHSE GYSIGKSLLE DEYIGIASSF 250
LKKAKELGVK VILPLDHIVA DDFNKNSIPE YIDSFNIPEN KIGMDIGANT 300
LKEIENVVKT AKTIIWNGPL GVFEFDSFSK GTAKVAEMVA SCSGLTVVGG 350
GDSVAAVNKF NLSDKITHVS TGGGASLEYL EGRILPGIKV LEN 393
Length:393
Mass (Da):42,346
Last modified:December 15, 1998 - v2
Checksum:iEB437EFD5F7AFFDE
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti164 – 1641L → S in AAB53931. 1 Publication
Sequence conflicti177 – 1782KF → NS in AAB53931. 1 Publication
Sequence conflicti190 – 1901F → S in AAB53931. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28760 Genomic DNA. Translation: AAB53931.1.
AE000783 Genomic DNA. Translation: AAC66451.1.
L32595 Genomic DNA. Translation: AAC41405.1.
PIRiH70106.
RefSeqiNP_212190.1. NC_001318.1.

Genome annotation databases

EnsemblBacteriaiAAC66451; AAC66451; BB_0056.
GeneIDi1194892.
KEGGibbu:BB_0056.
PATRICi20556717. VBIBorBur75917_0454.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28760 Genomic DNA. Translation: AAB53931.1 .
AE000783 Genomic DNA. Translation: AAC66451.1 .
L32595 Genomic DNA. Translation: AAC41405.1 .
PIRi H70106.
RefSeqi NP_212190.1. NC_001318.1.

3D structure databases

ProteinModelPortali Q59181.
SMRi Q59181. Positions 1-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224326.BB0056.

Proteomic databases

PRIDEi Q59181.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC66451 ; AAC66451 ; BB_0056 .
GeneIDi 1194892.
KEGGi bbu:BB_0056.
PATRICi 20556717. VBIBorBur75917_0454.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci BBUR224326:G9SO-55-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A glyceraldehyde-3-phosphate dehydrogenase homolog in Borrelia burgdorferi and Borrelia hermsii."
    Anda P., Gebbia J.A., Backenson P.B., Coleman J.L., Benach J.L.
    Infect. Immun. 64:262-268(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.
  3. "Conservation of gene arrangement and an unusual organization of rRNA genes in the linear chromosomes of the Lyme disease spirochaetes Borrelia burgdorferi, B. garinii and B. afzelii."
    Ojaimi C., Davidson B.E., Saint-Girons I., Old I.G.
    Microbiology 140:2931-2940(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 346-393.
    Strain: 212.

Entry informationi

Entry nameiPGK_BORBU
AccessioniPrimary (citable) accession number: Q59181
Secondary accession number(s): Q59186
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: June 11, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi