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Q59179

- TPIS_BUCAP

UniProt

Q59179 - TPIS_BUCAP

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Protein
Triosephosphate isomerase
Gene
tpiA, tpi, BUsg_297
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91Substrate By similarity
Binding sitei11 – 111Substrate By similarity
Active sitei96 – 961Electrophile By similarity
Active sitei168 – 1681Proton acceptor By similarity

GO - Molecular functioni

  1. triose-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
  3. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis, Pentose shunt

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-311-MONOMER.
UniPathwayiUPA00109; UER00189.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Triosephosphate isomerase (EC:5.3.1.1)
Short name:
TIM
Alternative name(s):
Triose-phosphate isomerase
Gene namesi
Name:tpiA
Synonyms:tpi
Ordered Locus Names:BUsg_297
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 254254Triosephosphate isomeraseUniRule annotation
PRO_0000090196Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi198804.BUsg297.

Structurei

3D structure databases

ProteinModelPortaliQ59179.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0149.
KOiK01803.
OMAiPAIYLDQ.
OrthoDBiEOG66QM23.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00147_B. TIM_B.
InterProiIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
PANTHERiPTHR21139. PTHR21139. 1 hit.
PfamiPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMiSSF51351. SSF51351. 1 hit.
TIGRFAMsiTIGR00419. tim. 1 hit.
PROSITEiPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59179-1 [UniParc]FASTAAdd to Basket

« Hide

MKKKIIAANW KLNGSIKTIS YFLTFLKSQI SSFLKNNIII IAPPTVFLER    50
VYKDINSINI HLAAQNIDVN LTGAFTGENS ALMMKDIGVK YIIIGHSERR 100
LLHNENNEII AKKFCLVKNL NLVPILCIGE TEAEKKSNKT EKILKEQLNS 150
IFNSFGEKAF RNAVIAYEPI WSIGTGVSAD PKNVQLIHKF IKNYIKKYDI 200
VSAENLIVQY GGSVTSLNAG NFLKQPDIDG LLIGSASLKH EEFLKIIKIS 250
DSFL 254
Length:254
Mass (Da):28,458
Last modified:November 1, 1997 - v1
Checksum:iDFA12B60F9E68E10
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43549 Genomic DNA. Translation: AAC05431.1.
AE013218 Genomic DNA. Translation: AAM67852.1.
RefSeqiNP_660641.1. NC_004061.1.
WP_011053819.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67852; AAM67852; BUsg_297.
GeneIDi1005501.
KEGGibas:BUsg297.
PATRICi21247403. VBIBucAph100086_0311.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43549 Genomic DNA. Translation: AAC05431.1 .
AE013218 Genomic DNA. Translation: AAM67852.1 .
RefSeqi NP_660641.1. NC_004061.1.
WP_011053819.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q59179.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg297.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67852 ; AAM67852 ; BUsg_297 .
GeneIDi 1005501.
KEGGi bas:BUsg297.
PATRICi 21247403. VBIBucAph100086_0311.

Phylogenomic databases

eggNOGi COG0149.
KOi K01803.
OMAi PAIYLDQ.
OrthoDBi EOG66QM23.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00189 .
UPA00138 .
BioCyci BAPH198804:GHMG-311-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00147_B. TIM_B.
InterProi IPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view ]
PANTHERi PTHR21139. PTHR21139. 1 hit.
Pfami PF00121. TIM. 1 hit.
[Graphical view ]
SUPFAMi SSF51351. SSF51351. 1 hit.
TIGRFAMsi TIGR00419. tim. 1 hit.
PROSITEi PS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of a DNA fragment from Buchnera aphidicola (Aphid endosymbiont) containing the genes aspS-trxB-serS-serC-aroA-rpsA-himD-tpiA."
    Thao M.L., Baumann P.
    Curr. Microbiol. 35:68-69(1997)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiTPIS_BUCAP
AccessioniPrimary (citable) accession number: Q59179
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 3, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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