Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q59110 (DSRB_ARCFU) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sulfite reductase, dissimilatory-type subunit beta
EC=1.8.99.3
Alternative name(s):
Hydrogensulfite reductase subunit beta
Gene names
Name:dsrB
Ordered Locus Names:AF_0424
OrganismArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifier224325 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.

Catalytic activity

(O3S.S.SO3)2- + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.

Cofactor

Binds 1 4Fe-4S cluster per subunit.

Binds 2 sirohemes per subunit.

Subunit structure

Heterotetramer of two alpha and two beta subunits.

Subcellular location

Membrane. Note: Although the protein complex is found in the soluble fraction it may be membrane-associated in vivo.

Sequence similarities

Contains 1 4Fe-4S ferredoxin-type domain.

Biophysicochemical properties

Temperature dependence:

Highly thermostable. Inactive towards methylviologen below 55 degrees Celsius.

Sequence caution

The sequence AAB90811.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366Sulfite reductase, dissimilatory-type subunit beta
PRO_0000080027

Regions

Domain232 – 262314Fe-4S ferredoxin-type

Sites

Metal binding1401Iron (heme axial ligand) Potential
Metal binding1781Iron (heme axial ligand) Potential
Metal binding1821Iron (heme axial ligand) Potential
Metal binding2201Iron-sulfur (4Fe-4S) Potential
Metal binding2411Iron-sulfur (4Fe-4S) Potential
Metal binding2441Iron-sulfur (4Fe-4S) Potential
Metal binding2471Iron-sulfur (4Fe-4S) Potential

Secondary structure

1 ................................................................... 366
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q59110 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: BA8E4C59216459DA

FASTA36641,570
        10         20         30         40         50         60 
MVVEGVKTDF GPPYFRDLLH PVIAKNYGKW KYHEVVKPGV IKRVAESGDV IYVVRFGTPR 

        70         80         90        100        110        120 
LLSIYTVREL CDIADKYSDG YLRWTSRNNV EFFVTDESKI DDLINEVQER VGFPCGGTWD 

       130        140        150        160        170        180 
AVKGEYGLSN IVHTQGWIHC HTPAIDASGI VKAVMDELYE YFTDHKLPAM CRISLACCAN 

       190        200        210        220        230        240 
MCGAVHASDI AIVGIHRTPP IPNDEAIRKT CEIPSTVAAC PTGALKPDMK NKTIKVDVEK 

       250        260        270        280        290        300 
CMYCGNCYTM CPGMPLFDPE NDGAAIMVGG KLSEARRMPE LSKVVVPWVP NEPPRWPTLV 

       310        320        330        340        350        360 
KYVKQILEAW AANANKHERL IEWVDRIGWE RFFELTGLEF TQHLIDDYRI TPYFYSEFRA 


STQFKW

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M95624 Genomic DNA. Translation: AAB17214.1.
AE000782 Genomic DNA. Translation: AAB90811.1. Different initiation.
PIRH69302.
RefSeqNP_069260.1. NC_000917.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3MM5X-ray1.80B/E1-366[»]
3MM6X-ray1.90B/E1-366[»]
3MM7X-ray1.90B/E1-366[»]
3MM8X-ray2.28B/E1-366[»]
3MM9X-ray2.10B/E1-366[»]
3MMAX-ray2.30B/E1-366[»]
3MMBX-ray2.30B/E1-366[»]
3MMCX-ray2.04B/E1-366[»]
ProteinModelPortalQ59110.
SMRQ59110. Positions 4-366.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1483640.
GenomeReviewsGene locus AF_0424 in contig AE000782_GR.
KEGGafu:AF0424.
NMPDRfig|224325.1.peg.419.
TIGRAF_0424.

Phylogenomic databases

HOGENOMHBG405736.
OMAWLHCDIP.
ProtClustDBCLSK862601.

Enzyme and pathway databases

BioCycAFUL224325:AF_0424-MONOMER.
MetaCyc:MONOMER-12501.

Family and domain databases

InterProIPR001450. 4Fe4S-bd_dom.
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR011808. DsrB.
IPR005117. NiRdtase/SiRdtase_haem-b_fer.
IPR006067. NO2/SO3_Rdtase_4Fe4S_dom.
[Graphical view]
KOK11181.
PfamPF00037. Fer4. 1 hit.
PF01077. NIR_SIR. 1 hit.
PF03460. NIR_SIR_ferr. 1 hit.
[Graphical view]
SUPFAMSSF55124. NiR_SiRalpha_1/3. 1 hit.
TIGRFAMsTIGR02066. DsrB. 1 hit.
PROSITEPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDSRB_ARCFU
AccessionPrimary (citable) accession number: Q59110
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 16, 2011
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents