Q59094 (SODM_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Mn]
EC=1.15.1.1

Gene names

Name:	sodA
Synonyms:	sodM
Ordered Locus Names:	ACIAD1070

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 manganese ion per subunit By similarity.
Subcellular location	Periplasm Probable.
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Ligand	Manganese Metal-binding
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 228	205	Superoxide dismutase [Mn]		PRO_0000032903
Sites
	Metal binding	49	1	Manganese By similarity
	Metal binding	100	1	Manganese By similarity
	Metal binding	188	1	Manganese By similarity
	Metal binding	192	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q59094 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4475C9AD9FFEE0F8	FASTA	228	25,741
	10 20 30 40 50 60 MTRSLKTTLI LLASSVISMS ALAEFKQAPL PYATNALQPA IDQQTMEIHY GKHHKAYVDN 70 80 90 100 110 120 LNAQIKTYPE LDKTDLIQLQ KQISKYNTAV RNNGGGHFNH TFFWESLAAT NKTGQPSPAL 130 140 150 160 170 180 VKQITQDFGS LDAFKQKFNE AASGRFGSGW AWLIVTPNGK LAVTSTPNQD NPLMDLSETK 190 200 210 220 GTPLLGLDVW EHAYYLKYQN RRADYIKAFW SVVNWNKVNE RYNEAIKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of a putative periplasmic Mn superoxide dismutase from Acinetobacter calcoaceticus ADP1." Geissdoerfer W., Ratajczak A., Hillen W. Gene 186:305-308(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ADP1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z46863 Genomic DNA. Translation: CAA86923.1. CR543861 Genomic DNA. Translation: CAG67957.1.
PIR	JC6320.
RefSeq	YP_045779.1. NC_005966.1.
3D structure databases
ProteinModelPortal	Q59094.
SMR	Q59094. Positions 24-225.
ModBase	Search...
Protein-protein interaction databases
STRING	62977.ACIAD1070.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG67957; CAG67957; ACIAD1070.
GeneID	2880832.
KEGG	aci:ACIAD1070.
PATRIC	20739990. VBIAciSp98416_0959.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0605.
HOGENOM	HOG000013584.
KO	K04564.
OMA	KFTETAT.
Enzyme and pathway databases
BioCyc	ASP62977:GJVV-1009-MONOMER.
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSF	PIRSF000349. SODismutase. 1 hit.
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODM_ACIAD

Accession

Primary (citable) accession number: Q59094

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program