Q59091 (PCAJ_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
3-oxoadipate CoA-transferase subunit B
EC=2.8.3.6

Alternative name(s):
Beta-ketoadipate:succinyl-CoA transferase subunit B

Gene names

Name:	pcaJ
Ordered Locus Names:	ACIAD1705
AND
Name:	catJ
Ordered Locus Names:	ACIAD1449

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.
Pathway	Aromatic compound metabolism; beta-ketoadipate pathway; acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2.
Subunit structure	Heterodimer By similarity.
Sequence similarities	Belongs to the 3-oxoacid CoA-transferase subunit B family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Molecular function	Transferase
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological_process	beta-ketoadipate pathway Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	3-oxoadipate CoA-transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 217	217	3-oxoadipate CoA-transferase subunit B		PRO_0000157917
Sites
	Active site	50	1	By similarity
Experimental info
	Sequence conflict	39	1	L → LM in AAC37147. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q59091 [UniParc]. Last modified August 31, 2004. Version 2. Checksum: 7630238C4DC39D16	FASTA	217	23,165
	10 20 30 40 50 60 MSYHKLTRDQ IAQRVAQDIP EGSYVNLGIG LPTKIASYLP ADKDVFLHSE NGLLAFGPPP 70 80 90 100 110 120 AAGEEDPELI NAGKEYVTML EGGCFFHHGD SFAMMRGGHL DICVLGAFQI AANGDLANWH 130 140 150 160 170 180 TGAPDAIPSV GGAMDLAVGA KKVFVTTDHV TKKGEPKIVA ELTYPATGQK CVDRIYTDLC 190 200 210 IIDVVPEGLK VIEKVEGLSF EELQRLTGAT LIDATQG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Contrasting patterns of evolutionary divergence within the Acinetobacter calcoaceticus pca operon." Kowalchuk G.A., Hartnett G.B., Benson A., Houghton J.E., Ngai K.-L., Ornston L.N. Gene 146:23-30(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-38 (PCAJ).
[2]	"Unusual G + C content and codon usage in catIJF, a segment of the ben-cat supra-operonic cluster in the Acinetobacter calcoaceticus chromosome." Shanley M.S., Harrison A., Parales R.E., Kowalchuk G., Mitchell D.J., Ornston L.N. Gene 138:59-65(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (CATJ).
[3]	"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (PCAJ AND CATJ). Strain: ADP1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L05770 Genomic DNA. Translation: AAC37147.1. AF009224 Genomic DNA. Translation: AAC46433.1. CR543861 Genomic DNA. Translation: CAG68312.1. CR543861 Genomic DNA. Translation: CAG68547.1.
PIR	B44570.
RefSeq	YP_046134.1. NC_005966.1. YP_046369.1. NC_005966.1.
3D structure databases
ProteinModelPortal	Q59091.
ModBase	Search...
Protein-protein interaction databases
STRING	62977.ACIAD1705.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG68312; CAG68312; ACIAD1449. CAG68547; CAG68547; ACIAD1705.
GeneID	2879439. 2879925.
KEGG	aci:ACIAD1449. aci:ACIAD1705.
PATRIC	20740708. VBIAciSp98416_1306.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2057.
HOGENOM	HOG000221245.
KO	K01032.
OMA	TWVMMDL.
ProtClustDB	CLSK707318.
Enzyme and pathway databases
BioCyc	ASP62977:GJVV-1376-MONOMER. ASP62977:GJVV-1617-MONOMER.
UniPathway	UPA00157; UER00262.
Family and domain databases
InterPro	IPR012791. 3-oxoacid_CoA-transf_B. IPR004165. CoA_trans_fam_I. IPR004164. CoA_transf_AS. [Graphical view]
PANTHER	PTHR13707. PTHR13707. 1 hit.
Pfam	PF01144. CoA_trans. 1 hit. [Graphical view]
SMART	SM00882. CoA_trans. 1 hit. [Graphical view]
TIGRFAMs	TIGR02428. pcaJ_scoB_fam. 1 hit.
PROSITE	PS01274. COA_TRANSF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCAJ_ACIAD

Accession

Primary (citable) accession number: Q59091
Secondary accession number(s): Q43934

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	August 31, 2004
Last modified:	May 1, 2013
This is version 85 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program