Reviewed, UniProtKB/Swiss-Prot Q59088 (G6PI_ACIAD)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	ACIAD0101

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	557 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 557	557	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000180580
Sites
	Active site	361	1	Proton donor By similarity
	Active site	392	1	By similarity
	Active site	520	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q59088-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: D74AF214B139E4DC	FASTA	557	63,280
	10 20 30 40 50 60 MNKNIEQFPR KTTLTPQQKL EQLMEQHKTV HLTELFDKEQ DRFAKYCVGC EDLVFDFSKQ 70 80 90 100 110 120 RINQPILDAL VQLAESKQLN KWIDTLFSQN KINYTEQREA MHWALRLPAD NQVYPELAKQ 130 140 150 160 170 180 VSDQLERMYQ LVNKIHEGQY RGATGEVIQD VVNIGVGGSD LGPLMVSHAL SDFKVKTAKP 190 200 210 220 230 240 LNIRFVSTMD GSQLSDILHQ LRPETTLFIV SSKSFSTIDT LSNAHTARKW LEKALGRESS 250 260 270 280 290 300 ILKSHFIGVS TKPDKMTEWG IHPDNQFLLW DWVGGRYSLW SCIGLPIALT IGVEGFKAFL 310 320 330 340 350 360 AGAHGIDEHF RTTEFHQNIP VLMGLMGIWN TNYLNLKTHA VLPYDGRLKY FTSYLQQLEM 370 380 390 400 410 420 ESNGKSTQRN GQKVENTTCP IVWGEVGPNA QHAFYQLLHQ GTQKVSCDFI APMHRYNANH 430 440 450 460 470 480 FTYVENADAL IDQHLLALSN CLAQSRLLAF GNDALKVDQR EQLPAYKQYE GNQPSTTMLL 490 500 510 520 530 540 KELSPRTMGK LIALYEHKVF VQSVIWDINP FDQWGVEKGK EIANDLLPIL NGESSDLSHL 550 DDSTQGLIQF LLGKSNG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stark M., Kaplan N., Ron E. Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	X89900 Genomic DNA. Translation: CAA61993.1. CR543861 Genomic DNA. Translation: CAG67079.1.
PIR	S58164.
RefSeq	YP_044901.1.
3D structure databases
HSSP	HSSP built from PDB template 1JIQ based on UniProtKB P06744.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59088.
Genome annotation databases
GeneID	2879592.
GenomeReviews	Gene locus ACIAD0101 in contig CR543861_GR.
KEGG	aci:ACIAD0101.
NMPDR	fig|62977.3.peg.16.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q59088.
OMA	LANSCEL.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD0101-MON.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_ACIAD

Accession

Primary (citable) accession number: Q59088

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	November 3, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)