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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei361Proton donorBy similarity1
Active sitei392By similarity1
Active sitei520By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciASP62977:G1GJ8-93-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:ACIAD0101
OrganismiAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Taxonomic identifieri62977 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter
Proteomesi
  • UP000000430 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001805801 – 557Glucose-6-phosphate isomeraseAdd BLAST557

Interactioni

Protein-protein interaction databases

STRINGi62977.ACIAD0101

Structurei

3D structure databases

ProteinModelPortaliQ59088
SMRiQ59088
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiSFIIPDD
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q59088-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKNIEQFPR KTTLTPQQKL EQLMEQHKTV HLTELFDKEQ DRFAKYCVGC
60 70 80 90 100
EDLVFDFSKQ RINQPILDAL VQLAESKQLN KWIDTLFSQN KINYTEQREA
110 120 130 140 150
MHWALRLPAD NQVYPELAKQ VSDQLERMYQ LVNKIHEGQY RGATGEVIQD
160 170 180 190 200
VVNIGVGGSD LGPLMVSHAL SDFKVKTAKP LNIRFVSTMD GSQLSDILHQ
210 220 230 240 250
LRPETTLFIV SSKSFSTIDT LSNAHTARKW LEKALGRESS ILKSHFIGVS
260 270 280 290 300
TKPDKMTEWG IHPDNQFLLW DWVGGRYSLW SCIGLPIALT IGVEGFKAFL
310 320 330 340 350
AGAHGIDEHF RTTEFHQNIP VLMGLMGIWN TNYLNLKTHA VLPYDGRLKY
360 370 380 390 400
FTSYLQQLEM ESNGKSTQRN GQKVENTTCP IVWGEVGPNA QHAFYQLLHQ
410 420 430 440 450
GTQKVSCDFI APMHRYNANH FTYVENADAL IDQHLLALSN CLAQSRLLAF
460 470 480 490 500
GNDALKVDQR EQLPAYKQYE GNQPSTTMLL KELSPRTMGK LIALYEHKVF
510 520 530 540 550
VQSVIWDINP FDQWGVEKGK EIANDLLPIL NGESSDLSHL DDSTQGLIQF

LLGKSNG
Length:557
Mass (Da):63,280
Last modified:November 1, 1996 - v1
Checksum:iD74AF214B139E4DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89900 Genomic DNA Translation: CAA61993.1
CR543861 Genomic DNA Translation: CAG67079.1
PIRiS58164
RefSeqiWP_004930760.1, NC_005966.1

Genome annotation databases

EnsemblBacteriaiCAG67079; CAG67079; ACIAD0101
KEGGiaci:ACIAD0101

Similar proteinsi

Entry informationi

Entry nameiG6PI_ACIAD
AccessioniPrimary (citable) accession number: Q59088
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: February 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome