Q59081 (SODC_AGGAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1

Gene names

Name:

sodC

Organism

Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans)

Taxonomic identifier

714 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Aggregatibacter

Protein attributes

Sequence length	87 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Periplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
Gene Ontology (GO)
Biological process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›87	›87	Superoxide dismutase [Cu-Zn]		PRO_0000164160
Sites
	Metal binding	18	1	Copper; catalytic By similarity
	Metal binding	18	1	Zinc; structural By similarity
	Metal binding	27	1	Zinc; structural By similarity
	Metal binding	36	1	Zinc; structural By similarity
	Metal binding	39	1	Zinc; structural By similarity
	Metal binding	74	1	Copper; catalytic By similarity
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	87	1

Sequences

	Sequence		Length	Mass (Da)
	Q59081 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 6704173D25976550	FASTA	87	9,287
	10 20 30 40 50 60 EPKEKDGKLT AGLGAGGHWD PKDTKQHGYP WQDDAHLGDL PALTVLHDGT AANPVLAPRI 70 80 KHLDDVRGHS LMIHAGGDNH SDHPAPL

References

[1]	"Bacterial [Cu,Zn]-superoxide dismutase: phylogenetically distinct from the eukaryotic enzyme, and not so rare after all!" Kroll J.S., Langford P.R., Wilks K.E., Keil A.D. Microbiology 141:2271-2279(1995) [PubMed: 7496539] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 43718 / FDC Y4 / Serotype b.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X83122 Genomic DNA. Translation: CAA58203.1.
PIR	I39485.
3D structure databases
ProteinModelPortal	Q59081.
SMR	Q59081. Positions 1-87.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001424. SOD_Cu_Zn_dom. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. Partial match. PS00332. SOD_CU_ZN_2. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC_AGGAC

Accession

Primary (citable) accession number: Q59081

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1996
Last modified:	July 27, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program