Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q59049 (APT_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Adenine phosphoribosyltransferase
Short name=APRT
EC=2.4.2.7
Gene names
Name:apt
Ordered Locus Names:MJ1655
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus

Protein attributes

Sequence length183 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. HAMAP MF_00004

Catalytic activity

AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004

Pathway

Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004

Subunit structure

Homodimer By similarity. HAMAP MF_00004

Subcellular location

Cytoplasm HAMAP MF_00004.

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Ontologies

Keywords
   Biological processPurine salvage
   Cellular componentCytoplasm
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processadenine salvage

Inferred from electronic annotation. Source: InterPro

purine ribonucleoside salvage

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionadenine phosphoribosyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 183183Adenine phosphoribosyltransferase HAMAP MF_00004
PRO_0000149496

Sequences

Sequence LengthMass (Da)Tools
Q59049 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: A20172DC74A941FB

FASTA18320,218
        10         20         30         40         50         60 
MLLEETLKSC PIVKRGEYHY FIHPISDGVP VVEPKLLREV ATRIIKIGDF EGATKLVTAE 

        70         80         90        100        110        120 
AMGIPLVTTL SLYTDIPYVI MRKREYKLPG EIPVFQSTGY SKGQLYLNGI EKGDKVVIID 

       130        140        150        160        170        180 
DVISTGGTMI AIIDALKRAG AEIKDIICVI ERGEGKKIVE EKTGYKIKTL VKIDVVDGKV 


VIL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L77117 Genomic DNA. Translation: AAB99676.1.
PIRE64506.
RefSeqNP_248665.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ59049.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1452564.
GenomeReviewsGene locus MJ1655 in contig L77117_GR.
KEGGmja:MJ_1655.
NMPDRfig|243232.1.peg.1702.
TIGRMJ1655.

Phylogenomic databases

HOGENOMHBG496859.
OMANYFIHPI.
ProtClustDBPRK02304.

Enzyme and pathway databases

BioCycMJAN243232:MJ_1655-MONOMER.

Family and domain databases

HAMAPMF_00004. Aden_phosphoribosyltr.
[Tree]
InterProIPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase.
[Graphical view]
KOK00759.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
PROSITEPS00103. PUR_PYR_PR_TRANSFER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPT_METJA
AccessionPrimary (citable) accession number: Q59049
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 16, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents