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Q58FF3

- ENPLL_HUMAN

UniProt

Q58FF3 - ENPLL_HUMAN

Protein

Putative endoplasmin-like protein

Gene

HSP90B2P

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Putative molecular chaperone.By similarity

    GO - Molecular functioni

    1. ATP binding Source: InterPro

    GO - Biological processi

    1. protein folding Source: InterPro
    2. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative endoplasmin-like protein
    Alternative name(s):
    Putative heat shock protein 90 kDa beta member 2
    Gene namesi
    Name:HSP90B2P
    Synonyms:GRP94B, GRP94P1, TRAP1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:12099. HSP90B2P.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Putative endoplasmin-like proteinPRO_0000349258Add
    BLAST

    Proteomic databases

    MaxQBiQ58FF3.
    PaxDbiQ58FF3.
    PRIDEiQ58FF3.

    Expressioni

    Gene expression databases

    CleanExiHS_TRAP1.
    GenevestigatoriQ58FF3.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000368186.

    Structurei

    3D structure databases

    ProteinModelPortaliQ58FF3.
    SMRiQ58FF3. Positions 6-355.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the heat shock protein 90 family.Curated

    Phylogenomic databases

    eggNOGiCOG0326.
    HOGENOMiHOG000031988.
    HOVERGENiHBG007374.
    InParanoidiQ58FF3.
    PhylomeDBiQ58FF3.

    Family and domain databases

    InterProiIPR001404. Hsp90_fam.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    [Graphical view]
    PANTHERiPTHR11528. PTHR11528. 1 hit.
    PfamiPF00183. HSP90. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q58FF3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV    50
    PRGLFDEYGS KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS 100
    LNVSCETLQQ HKLLKVIRKK LVHKTLDMIK KIADEKYNDT FWKEFGTNIK 150
    LGVIEDHSNR TCLAKLLRFQ SSHHPADITS LHQDVERMKE KQDKICLMAG 200
    GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS EKTKESHEAV 250
    EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI 300
    MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL 350
    DLAVVEEPDE EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL 399
    Length:399
    Mass (Da):45,859
    Last modified:April 26, 2005 - v1
    Checksum:i8DB8E2D7E202E3CE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY956768 mRNA. Translation: AAX38255.1.
    UniGeneiHs.656611.

    Genome annotation databases

    UCSCiuc031quj.1. human.

    Polymorphism databases

    DMDMi74706932.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY956768 mRNA. Translation: AAX38255.1 .
    UniGenei Hs.656611.

    3D structure databases

    ProteinModelPortali Q58FF3.
    SMRi Q58FF3. Positions 6-355.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000368186.

    Polymorphism databases

    DMDMi 74706932.

    Proteomic databases

    MaxQBi Q58FF3.
    PaxDbi Q58FF3.
    PRIDEi Q58FF3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc031quj.1. human.

    Organism-specific databases

    GeneCardsi GC15P099797.
    HGNCi HGNC:12099. HSP90B2P.
    neXtProti NX_Q58FF3.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0326.
    HOGENOMi HOG000031988.
    HOVERGENi HBG007374.
    InParanoidi Q58FF3.
    PhylomeDBi Q58FF3.

    Gene expression databases

    CleanExi HS_TRAP1.
    Genevestigatori Q58FF3.

    Family and domain databases

    InterProi IPR001404. Hsp90_fam.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    [Graphical view ]
    PANTHERi PTHR11528. PTHR11528. 1 hit.
    Pfami PF00183. HSP90. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The HSP90 family of genes in the human genome: insights into their divergence and evolution."
      Chen B., Piel W.H., Gui L., Bruford E., Monteiro A.
      Genomics 86:627-637(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiENPLL_HUMAN
    AccessioniPrimary (citable) accession number: Q58FF3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Could be the product of a pseudogene.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3