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Protein

Putative endoplasmin-like protein

Gene

HSP90B2P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Putative molecular chaperone.By similarity

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative endoplasmin-like protein
Alternative name(s):
Putative heat shock protein 90 kDa beta member 2
Gene namesi
Name:HSP90B2P
Synonyms:GRP94B, GRP94P1, TRAP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:12099 HSP90B2P
neXtProtiNX_Q58FF3

Pathology & Biotechi

Organism-specific databases

DisGeNETi7190

Polymorphism and mutation databases

DMDMi74706932

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003492581 – 399Putative endoplasmin-like proteinAdd BLAST399

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki130Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

EPDiQ58FF3
MaxQBiQ58FF3
PeptideAtlasiQ58FF3
PRIDEiQ58FF3

PTM databases

iPTMnetiQ58FF3
PhosphoSitePlusiQ58FF3
SwissPalmiQ58FF3

Expressioni

Gene expression databases

CleanExiHS_TRAP1

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ58FF3, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ58FF3
SMRiQ58FF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 90 family.Curated

Phylogenomic databases

HOGENOMiHOG000031988
HOVERGENiHBG007374
InParanoidiQ58FF3
PhylomeDBiQ58FF3

Family and domain databases

Gene3Di1.20.120.790, 1 hit
InterProiView protein in InterPro
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit

Sequencei

Sequence statusi: Complete.

Q58FF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV
60 70 80 90 100
PRGLFDEYGS KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS
110 120 130 140 150
LNVSCETLQQ HKLLKVIRKK LVHKTLDMIK KIADEKYNDT FWKEFGTNIK
160 170 180 190 200
LGVIEDHSNR TCLAKLLRFQ SSHHPADITS LHQDVERMKE KQDKICLMAG
210 220 230 240 250
GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS EKTKESHEAV
260 270 280 290 300
EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI
310 320 330 340 350
MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL
360 370 380 390
DLAVVEEPDE EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL
Length:399
Mass (Da):45,859
Last modified:April 26, 2005 - v1
Checksum:i8DB8E2D7E202E3CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY956768 mRNA Translation: AAX38255.1
UniGeneiHs.656611

Similar proteinsi

Entry informationi

Entry nameiENPLL_HUMAN
AccessioniPrimary (citable) accession number: Q58FF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health