Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative endoplasmin-like protein

Gene

HSP90B2P

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Putative molecular chaperone.By similarity

GO - Molecular functioni

  1. ATP binding Source: InterPro

GO - Biological processi

  1. protein folding Source: InterPro
  2. response to stress Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative endoplasmin-like protein
Alternative name(s):
Putative heat shock protein 90 kDa beta member 2
Gene namesi
Name:HSP90B2P
Synonyms:GRP94B, GRP94P1, TRAP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:12099. HSP90B2P.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Putative endoplasmin-like proteinPRO_0000349258Add
BLAST

Proteomic databases

MaxQBiQ58FF3.
PaxDbiQ58FF3.
PRIDEiQ58FF3.

Expressioni

Gene expression databases

CleanExiHS_TRAP1.
GenevestigatoriQ58FF3.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000368186.

Structurei

3D structure databases

ProteinModelPortaliQ58FF3.
SMRiQ58FF3. Positions 6-355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 90 family.Curated

Phylogenomic databases

eggNOGiCOG0326.
HOGENOMiHOG000031988.
HOVERGENiHBG007374.
InParanoidiQ58FF3.
PhylomeDBiQ58FF3.

Family and domain databases

InterProiIPR001404. Hsp90_fam.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58FF3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV
60 70 80 90 100
PRGLFDEYGS KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS
110 120 130 140 150
LNVSCETLQQ HKLLKVIRKK LVHKTLDMIK KIADEKYNDT FWKEFGTNIK
160 170 180 190 200
LGVIEDHSNR TCLAKLLRFQ SSHHPADITS LHQDVERMKE KQDKICLMAG
210 220 230 240 250
GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS EKTKESHEAV
260 270 280 290 300
EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI
310 320 330 340 350
MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL
360 370 380 390
DLAVVEEPDE EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL
Length:399
Mass (Da):45,859
Last modified:April 26, 2005 - v1
Checksum:i8DB8E2D7E202E3CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY956768 mRNA. Translation: AAX38255.1.
UniGeneiHs.656611.

Genome annotation databases

UCSCiuc031quj.1. human.

Polymorphism databases

DMDMi74706932.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY956768 mRNA. Translation: AAX38255.1.
UniGeneiHs.656611.

3D structure databases

ProteinModelPortaliQ58FF3.
SMRiQ58FF3. Positions 6-355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000368186.

Polymorphism databases

DMDMi74706932.

Proteomic databases

MaxQBiQ58FF3.
PaxDbiQ58FF3.
PRIDEiQ58FF3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc031quj.1. human.

Organism-specific databases

GeneCardsiGC15P099797.
HGNCiHGNC:12099. HSP90B2P.
neXtProtiNX_Q58FF3.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG0326.
HOGENOMiHOG000031988.
HOVERGENiHBG007374.
InParanoidiQ58FF3.
PhylomeDBiQ58FF3.

Gene expression databases

CleanExiHS_TRAP1.
GenevestigatoriQ58FF3.

Family and domain databases

InterProiIPR001404. Hsp90_fam.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The HSP90 family of genes in the human genome: insights into their divergence and evolution."
    Chen B., Piel W.H., Gui L., Bruford E., Monteiro A.
    Genomics 86:627-637(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiENPLL_HUMAN
AccessioniPrimary (citable) accession number: Q58FF3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 26, 2005
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.