Q58FF3 (ENPLL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative endoplasmin-like protein

Alternative name(s):
Putative heat shock protein 90 kDa beta member 2

Gene names

Name:	HSP90B2P
Synonyms:	GRP94B, GRP94P1, TRAP1

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	Putative molecular chaperone By similarity.
Sequence similarities	Belongs to the heat shock protein 90 family.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Biological process	Stress response
Molecular function	Chaperone
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: InterPro response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	Putative endoplasmin-like protein		PRO_0000349258

Sequences

	Sequence		Length	Mass (Da)
	Q58FF3 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 8DB8E2D7E202E3CE	FASTA	399	45,859
	10 20 30 40 50 60 MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV PRGLFDEYGS 70 80 90 100 110 120 KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS LNVSCETLQQ HKLLKVIRKK 130 140 150 160 170 180 LVHKTLDMIK KIADEKYNDT FWKEFGTNIK LGVIEDHSNR TCLAKLLRFQ SSHHPADITS 190 200 210 220 230 240 LHQDVERMKE KQDKICLMAG GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS 250 260 270 280 290 300 EKTKESHEAV EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI 310 320 330 340 350 360 MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL DLAVVEEPDE 370 380 390 EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL

References

[1]	"The HSP90 family of genes in the human genome: insights into their divergence and evolution." Chen B., Piel W.H., Gui L., Bruford E., Monteiro A. Genomics 86:627-637(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY956768 mRNA. Translation: AAX38255.1.
IPI	IPI00556538.
UniGene	Hs.656611.
3D structure databases
HSSP	HSSP built from PDB template 1USV based on UniProtKB P02829.
ProteinModelPortal	Q58FF3.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000368186.
Polymorphism databases
DMDM	74706932.
Proteomic databases
PaxDb	Q58FF3.
PRIDE	Q58FF3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
GeneCards	GC15P099797.
HGNC	HGNC:12099. HSP90B2P.
neXtProt	NX_Q58FF3.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0326.
HOGENOM	HOG000031988.
HOVERGEN	HBG007374.
InParanoid	Q58FF3.
OrthoDB	EOG41C6WG.
Gene expression databases
CleanEx	HS_TRAP1.
Genevestigator	Q58FF3.
Family and domain databases
InterPro	IPR001404. Hsp90. IPR020568. Ribosomal_S5_D2-typ_fold. [Graphical view]
PANTHER	PTHR11528. PTHR11528. 1 hit.
Pfam	PF00183. HSP90. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
PROSITE	PS00014. ER_TARGET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ENPLL_HUMAN

Accession

Primary (citable) accession number: Q58FF3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	April 26, 2005
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.