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Q58FF3 (ENPLL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative endoplasmin-like protein
Alternative name(s):
Putative heat shock protein 90 kDa beta member 2
Gene names
Name:HSP90B2P
Synonyms:GRP94B, GRP94P1, TRAP1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Putative molecular chaperone By similarity.

Sequence similarities

Belongs to the heat shock protein 90 family.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   Biological processStress response
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Putative endoplasmin-like protein
PRO_0000349258

Sequences

Sequence LengthMass (Da)Tools
Q58FF3 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 8DB8E2D7E202E3CE

FASTA39945,859
        10         20         30         40         50         60 
MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV PRGLFDEYGS 

        70         80         90        100        110        120 
KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS LNVSCETLQQ HKLLKVIRKK 

       130        140        150        160        170        180 
LVHKTLDMIK KIADEKYNDT FWKEFGTNIK LGVIEDHSNR TCLAKLLRFQ SSHHPADITS 

       190        200        210        220        230        240 
LHQDVERMKE KQDKICLMAG GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS 

       250        260        270        280        290        300 
EKTKESHEAV EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI 

       310        320        330        340        350        360 
MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL DLAVVEEPDE 

       370        380        390 
EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL 

« Hide

References

[1]"The HSP90 family of genes in the human genome: insights into their divergence and evolution."
Chen B., Piel W.H., Gui L., Bruford E., Monteiro A.
Genomics 86:627-637(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY956768 mRNA. Translation: AAX38255.1.
UniGeneHs.656611.

3D structure databases

ProteinModelPortalQ58FF3.
SMRQ58FF3. Positions 6-355.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000368186.

Polymorphism databases

DMDM74706932.

Proteomic databases

PaxDbQ58FF3.
PRIDEQ58FF3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc031quj.1. human.

Organism-specific databases

GeneCardsGC15P099797.
HGNCHGNC:12099. HSP90B2P.
neXtProtNX_Q58FF3.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0326.
HOGENOMHOG000031988.
HOVERGENHBG007374.
InParanoidQ58FF3.
PhylomeDBQ58FF3.

Gene expression databases

CleanExHS_TRAP1.
GenevestigatorQ58FF3.

Family and domain databases

InterProIPR015566. Endoplasmin.
IPR001404. Hsp90_fam.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR11528. PTHR11528. 1 hit.
PTHR11528:SF21. PTHR11528:SF21. 1 hit.
PfamPF00183. HSP90. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameENPLL_HUMAN
AccessionPrimary (citable) accession number: Q58FF3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: April 26, 2005
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM