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Protein
Submitted name:

SMC4 protein

Gene

SMC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
SMC4 proteinImported
Gene namesi
Name:SMC4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ58F29.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000341382.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini83 – 221139SMC_NInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili327 – 37549Sequence analysisAdd
BLAST
Coiled coili397 – 43135Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0996. Eukaryota.
COG1196. LUCA.
HOGENOMiHOG000184777.
HOVERGENiHBG082271.
KOiK06675.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q58F29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRKGTQPST ARRREEGPPP PSPDGASSDA EPEPPSGRTE SPATAAETAS
60 70 80 90 100
EELDNRSLEE ILNSIPPPPP PAMTNEAGAP RLMITHIVNQ NFKSYAGEKI
110 120 130 140 150
LGPFHKRFSC IIGPNGSGKS NVIDSMLFVF GYRAQKIRSK KLSVLIHNSD
160 170 180 190 200
EHKDIQSCTV EVHFQKIIDK EGDDYEVIPN SNFYVSRTAC RDNTSVYHIS
210 220 230 240 250
GKKKTFKDVG NLLRSHGIDL DHNRFLILQG EVEQIAMMKP KGQTEHDEGM
260 270 280 290 300
LEYLEDIIGC GRLNEPIKVL CRRVEILNEH RGEKLNRVKM VEKEKDALEG
310 320 330 340 350
EKNIAIEFLT LENEIFRKKN HVCQYYIYEL QKRIAEMETQ KEKIHEDTKE
360 370 380 390 400
INEKSNILSN EMKAKNKDVK DTEKKLNKIT KFIEENKEKF TQLDLEDVQV
410 420 430 440 450
REKLKHATSK AKKLEKQLQK DKEKVEEFKS IPAKSNNIIN ETTTRNNALE

KEKEKKKKK
Length:459
Mass (Da):52,529
Last modified:April 26, 2005 - v1
Checksum:i7C05BA76DC41D20F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei459 – 4591Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC001557 mRNA. Translation: AAH01557.1.
BC106033 mRNA. Translation: AAI06034.1.
RefSeqiNP_001002800.1. NM_001002800.2.
NP_001275682.1. NM_001288753.1.
UniGeneiHs.58992.

Genome annotation databases

GeneIDi10051.
KEGGihsa:10051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC001557 mRNA. Translation: AAH01557.1.
BC106033 mRNA. Translation: AAI06034.1.
RefSeqiNP_001002800.1. NM_001002800.2.
NP_001275682.1. NM_001288753.1.
UniGeneiHs.58992.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000341382.

Proteomic databases

PeptideAtlasiQ58F29.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10051.
KEGGihsa:10051.

Organism-specific databases

CTDi10051.

Phylogenomic databases

eggNOGiKOG0996. Eukaryota.
COG1196. LUCA.
HOGENOMiHOG000184777.
HOVERGENiHBG082271.
KOiK06675.

Miscellaneous databases

GenomeRNAii10051.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: CervixImported and PlacentaImported.

Entry informationi

Entry nameiQ58F29_HUMAN
AccessioniPrimary (citable) accession number: Q58F29
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 6, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.