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Protein
Submitted name:

Kelch-like 9 (Drosophila)

Gene

KLHL9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Kelch-like 9 (Drosophila)Imported
Submitted name:
cDNA FLJ34396 fis, clone HCHON2000826, highly similar to Kelch-like protein 9Imported
Gene namesi
Name:KLHL9Imported
ORF Names:hCG_1647676Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38662.

Expressioni

Gene expression databases

BgeeiENSG00000198642.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000351933.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 119BTB (POZ)InterPro annotationAdd BLAST70

Sequence similaritiesi

Contains 1 BTB (POZ) domain.UniRule annotation

Keywords - Domaini

Kelch repeatSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
HOVERGENiHBG106526.
KOiK10447.
OMAiCRWLRYE.
OrthoDBiEOG091G039V.

Family and domain databases

Gene3Di2.130.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR015916. Gal_Oxidase_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 5 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58EZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVSLGNGEM GVSAHLQPCK AGTTRFFTSN THSSVVLQGF DQLRIEGLLC
60 70 80 90 100
DVTLVPGDGD EIFPVHRAMM ASASDYFKAM FTGGMKEQDL MCIKLHGVNK
110 120 130 140 150
VGLKKIIDFI YTAKLSLNMD NLQDTLEAAS FLQILPVLDF CKVFLISGVS
160 170 180 190 200
LDNCVEVGRI ANTYNLIEVD KYVNNFILKN FPALLSTGEF LKLPFERLAF
210 220 230 240 250
VLSSNSLKHC TELELFKAAC RWLRLEDPRM DYAAKLMKNI RFPLMTPQDL
260 270 280 290 300
INYVQTVDFM RTDNTCVNLL LEASNYQMMP YMQPVMQSDR TAIRSDSTHL
310 320 330 340 350
VTLGGVLRQQ LVVSKELRMY DERAQEWRSL APMDAPRYQH GIAVIGNFLY
360 370 380 390 400
VVGGQSNYDT KGKTAVDTVF RFDPRYNKWM QVASLNEKRT FFHLSALKGH
410 420 430 440 450
LYAVGGRSAA GELATVECYN PRMNEWSYVA KMSEPHYGHA GTVYGGLMYI
460 470 480 490 500
SGGITHDTFQ NELMCFDPDT DKWMQKAPMT TVRGLHCMCT VGDKLYVIGG
510 520 530 540 550
NHFRGTSDYD DVLSCEYYSP TLDQWTPIAA MLRGQSDVGV AVFENKIYVV
560 570 580 590 600
GGYSWNNRCM VEIVQKYDPE KDEWHKVFDL PESLGGIRAC TLTVFPPEEN
610
PGSPSRESPL SAPSDHS
Length:617
Mass (Da):69,429
Last modified:February 5, 2008 - v1
Checksum:iB74232F28ABF7C82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039133 mRNA. Translation: AAH39133.1.
BC105008 mRNA. Translation: AAI05009.1.
BC113513 mRNA. Translation: AAI13514.1.
AK091715 mRNA. Translation: BAG52403.1.
CH471071 Genomic DNA. Translation: EAW58614.1.
RefSeqiNP_061335.1. NM_018847.3.
UniGeneiHs.701778.
Hs.710126.
Hs.744736.

Genome annotation databases

GeneIDi55958.
KEGGihsa:55958.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039133 mRNA. Translation: AAH39133.1.
BC105008 mRNA. Translation: AAI05009.1.
BC113513 mRNA. Translation: AAI13514.1.
AK091715 mRNA. Translation: BAG52403.1.
CH471071 Genomic DNA. Translation: EAW58614.1.
RefSeqiNP_061335.1. NM_018847.3.
UniGeneiHs.701778.
Hs.710126.
Hs.744736.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000351933.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55958.
KEGGihsa:55958.

Organism-specific databases

CTDi55958.
PharmGKBiPA38662.

Phylogenomic databases

eggNOGiKOG4441. Eukaryota.
ENOG410XNX8. LUCA.
HOVERGENiHBG106526.
KOiK10447.
OMAiCRWLRYE.
OrthoDBiEOG091G039V.

Miscellaneous databases

GenomeRNAii55958.

Gene expression databases

BgeeiENSG00000198642.

Family and domain databases

Gene3Di2.130.10.80. 1 hit.
InterProiIPR011705. BACK.
IPR017096. BTB-kelch_protein.
IPR000210. BTB/POZ_dom.
IPR015916. Gal_Oxidase_b-propeller.
IPR006652. Kelch_1.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF07707. BACK. 1 hit.
PF00651. BTB. 1 hit.
PF01344. Kelch_1. 5 hits.
[Graphical view]
PIRSFiPIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTiSM00875. BACK. 1 hit.
SM00225. BTB. 1 hit.
SM00612. Kelch. 6 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ58EZ4_HUMAN
AccessioniPrimary (citable) accession number: Q58EZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.