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Protein
Submitted name:

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Gene

SMARCC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1Imported
Gene namesi
Name:SMARCC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35954.

PTM / Processingi

Proteomic databases

PaxDbiQ58EY4.
PeptideAtlasiQ58EY4.
PRIDEiQ58EY4.

Expressioni

Gene expression databases

GenevisibleiQ58EY4. HS.

Interactioni

Protein-protein interaction databases

MINTiMINT-1689601.
STRINGi9606.ENSP00000254480.

Structurei

3D structure databases

ProteinModelPortaliQ58EY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini449 – 546SWIRMInterPro annotationAdd BLAST98
Domaini618 – 669SANTInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili914 – 945Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
HOVERGENiHBG054849.
KOiK11649.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR030087. BAF155.
IPR001357. BRCT_dom.
IPR000953. Chromo/shadow_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR032451. SMARCC_C.
IPR032450. SMARCC_N.
IPR007526. SWIRM.
IPR032448. SWIRM-assoc.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR12802:SF9. PTHR12802:SF9. 1 hit.
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
PF16496. SWIRM-assoc_2. 1 hit.
PF16498. SWIRM-assoc_3. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52113. SSF52113. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58EY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAGGGGP GTAVGATGSG IAAAAAGLAV YRRKDGGPDT KFWESPETVS
60 70 80 90 100
QLDSVRVWLG KHYKKYVHAD APTNKTLAGL VVQLLQFQED AFGKHVTNPA
110 120 130 140 150
FTKLPAKCFM DFKAGGALCH ILGAAYKYKN EQGWRRFDLQ NPSRMDRNVE
160 170 180 190 200
MFMNIEKTLV QNNCLTRPNI YLIPDIDLKL ANKLKDIIKR HQGTFTDEKS
210 220 230 240 250
KASHHIYPYS SSQDDEEWLR PVMRKEKQVL VHWGFYPDSY DTWVHSNDVD
260 270 280 290 300
AEIEDPPIPE KPWKVHVKWI LDTDIFNEWM NEEDYEVDEN RKPVSFRQRI
310 320 330 340 350
STKNEEPVRS PERRDRKASA NARKRKHSPS PPPPTPTESR KKSGKKGQAS
360 370 380 390 400
LYGKRRSQKE EDEQEDLTKD MEDPTPVPNI EEVVLPKNVN LKKDSENTPV
410 420 430 440 450
KGGTVADLDE QDEETVTAGG KEDEDPAKGD QSRSVDLGED NVTEQTNHII
460 470 480 490 500
IPSYASWFDY NCIHVIERRA LPEFFNGKNK SKTPEIYLAY RNFMIDTYRL
510 520 530 540 550
NPQEYLTSTA CRRNLTGDVC AVMRVHAFLE QWGLVNYQVD PESRPMAMGP
560 570 580 590 600
PPTPHFNVLA DTPSGLVPLH LRSPQVPAAQ QMLNFPEKNK EKPVDLQNFG
610 620 630 640 650
LRTDIYSKKT LAKSKGASAG REWTEQETLL LLEALEMYKD DWNKVSEHVG
660 670 680 690 700
SRTQDECILH FLRLPIEDPY LENSDASLGP LAYQPVPFSQ SGNPVMSTVA
710 720 730 740 750
FLASVVDPRV ASAAAKAALE EFSRVREEVP LELVEAHVKK VQEAARASGK
760 770 780 790 800
VDPTYGLESS CIAGTGPDEP EKLEGAEEEK MEADPDGQQP EKAENKVENE
810 820 830 840 850
TDEGDKAQDG ENEKNSEKEQ DSEVSEDTKS EEKETEENKE LTDTCKERES
860 870 880 890 900
DTGKKKVEHE ISEGNVATAA AAALASAATK AKHLAAVEER KIKSLVALLV
910 920 930 940 950
ETQMKKLEIK LRHFEELETI MDREKEALEQ QRQQLLTERQ NFHMEQLKYA
960 970 980 990 1000
ELRARQQMEQ QQHGQNPQQA HQHSGGPGLA PLGAAGHPGM MPHQQPPPYP
1010 1020 1030 1040 1050
LMHHQMPPPH PPQPGQIPGP GSMMPGQHMP GRMIPTVAAN IHPSGSGPTP
1060 1070 1080 1090 1100
PGMPPMPGNI LGPRVPLTAP NGMYPPPPQQ QPPPPPPADG VPPPPAPGPP

ASAAP
Length:1,105
Mass (Da):122,911
Last modified:April 26, 2005 - v1
Checksum:i86BB4F0F1572AFE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050564 mRNA. Translation: AAH50564.1.
RefSeqiNP_003065.3. NM_003074.3.
UniGeneiHs.476179.

Genome annotation databases

GeneIDi6599.
KEGGihsa:6599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC050564 mRNA. Translation: AAH50564.1.
RefSeqiNP_003065.3. NM_003074.3.
UniGeneiHs.476179.

3D structure databases

ProteinModelPortaliQ58EY4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1689601.
STRINGi9606.ENSP00000254480.

Proteomic databases

PaxDbiQ58EY4.
PeptideAtlasiQ58EY4.
PRIDEiQ58EY4.

Protocols and materials databases

DNASUi6599.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6599.
KEGGihsa:6599.

Organism-specific databases

CTDi6599.
PharmGKBiPA35954.

Phylogenomic databases

eggNOGiKOG1279. Eukaryota.
COG5259. LUCA.
HOVERGENiHBG054849.
KOiK11649.

Miscellaneous databases

ChiTaRSiSMARCC1. human.
GenomeRNAii6599.

Gene expression databases

GenevisibleiQ58EY4. HS.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.10.60. 1 hit.
InterProiIPR030087. BAF155.
IPR001357. BRCT_dom.
IPR000953. Chromo/shadow_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR032451. SMARCC_C.
IPR032450. SMARCC_N.
IPR007526. SWIRM.
IPR032448. SWIRM-assoc.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR12802:SF9. PTHR12802:SF9. 1 hit.
PfamiPF00249. Myb_DNA-binding. 1 hit.
PF04433. SWIRM. 1 hit.
PF16495. SWIRM-assoc_1. 1 hit.
PF16496. SWIRM-assoc_2. 1 hit.
PF16498. SWIRM-assoc_3. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
SM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF52113. SSF52113. 2 hits.
PROSITEiPS51293. SANT. 1 hit.
PS50934. SWIRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ58EY4_HUMAN
AccessioniPrimary (citable) accession number: Q58EY4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.