UniProtKB - Q58DQ3 (RL6_BOVIN)
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Protein
60S ribosomal protein L6
Gene
RPL6
Organism
Bos taurus (Bovine)
Status
Functioni
Component of the large ribosomal subunit.By similarity
GO - Molecular functioni
- RNA binding Source: GO_Central
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- cytoplasmic translation Source: UniProtKB
- ribosomal large subunit assembly Source: GO_Central
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC). R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L6 |
Gene namesi | Name:RPL6 |
Organismi | Bos taurus (Bovine) |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000171007 | 1 – 287 | 60S ribosomal protein L6Add BLAST | 287 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Cross-linki | 5 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 93 | N6-succinyllysineBy similarity | 1 | |
Modified residuei | 126 | PhosphoserineBy similarity | 1 | |
Modified residuei | 206 | N6-succinyllysineBy similarity | 1 | |
Modified residuei | 238 | N6-acetyllysineBy similarity | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
PaxDbi | Q58DQ3. |
PeptideAtlasi | Q58DQ3. |
PRIDEi | Q58DQ3. |
Interactioni
Subunit structurei
Component of the large ribosomal subunit (By similarity). May bind IPO9 with low affinity (By similarity).By similarity
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000042411. |
Family & Domainsi
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL6 family.Curated
Phylogenomic databases
eggNOGi | KOG1694. Eukaryota. COG2163. LUCA. |
GeneTreei | ENSGT00390000003682. |
HOGENOMi | HOG000207317. |
HOVERGENi | HBG002565. |
InParanoidi | Q58DQ3. |
KOi | K02934. |
OMAi | RKGDKPH. |
OrthoDBi | EOG091G0L13. |
TreeFami | TF300115. |
Family and domain databases
Gene3Di | 2.30.30.30. 1 hit. |
InterProi | View protein in InterPro IPR000915. 60S_ribosomal_L6E. IPR014722. Rib_L2_dom2. IPR005568. Ribosomal_L6_N. IPR008991. Translation_prot_SH3-like_sf. |
PANTHERi | PTHR10715. PTHR10715. 2 hits. |
Pfami | View protein in Pfam PF01159. Ribosomal_L6e. 1 hit. PF03868. Ribosomal_L6e_N. 1 hit. |
SUPFAMi | SSF50104. SSF50104. 1 hit. |
PROSITEi | View protein in PROSITE PS01170. RIBOSOMAL_L6E. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q58DQ3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGEKAEKPD TKEKKPEAKK ADAGKKAKKV EKVKKVKKGK PHCSRNPVLV
60 70 80 90 100
RGIGRYSRSA MYSRKALYKR KYSAAKSKVE KKKKVRVLAT VTKPVGGDKN
110 120 130 140 150
GGTRVVKLRK MPRYYPTEDV PRKLLSHGKK PFSKHVRKLR ASITPGTILI
160 170 180 190 200
ILTGRHRGKR VVFLKQLGSG LLLVTGPLSL NRVPLRRTHQ KFVIATSTKI
210 220 230 240 250
DISGVKIPEH LTDTYFKKKK LRKPRHQEGE IFDTEREKYE ITEQRKVDQK
260 270 280
AVDSQILRRI KAVPQLQGYL RSVFALTNGI YPHKVVF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BT021543 mRNA. Translation: AAX46390.1. BT021544 mRNA. Translation: AAX46391.1. AY911360 mRNA. Translation: AAW82124.1. BC133430 mRNA. Translation: AAI33431.1. |
RefSeqi | NP_001026926.1. NM_001031756.2. XP_005217842.1. XM_005217785.2. XP_005217843.1. XM_005217786.2. |
UniGenei | Bt.62205. |
Genome annotation databases
Ensembli | ENSBTAT00000033359; ENSBTAP00000042411; ENSBTAG00000031723. |
GeneIDi | 511051. |
KEGGi | bta:511051. |
Similar proteinsi
Entry informationi
Entry namei | RL6_BOVIN | |
Accessioni | Q58DQ3Primary (citable) accession number: Q58DQ3 Secondary accession number(s): A3KMZ3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | January 23, 2007 | |
Last modified: | March 28, 2018 | |
This is version 91 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |