RPL6

Functionⁱ

Enzyme and pathway databases

Reactomeⁱ	R-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression. R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane. R-BTA-6791226. Major pathway of rRNA processing in the nucleolus. R-BTA-72689. Formation of a pool of free 40S subunits. R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit. R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC). R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Reactomeⁱ

R-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S ribosomal protein L6
Gene namesⁱ	Name:RPL6
Organismⁱ	Bos taurus (Bovine)
Taxonomic identifierⁱ	9913 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos
Proteomesⁱ	UP000009136 Componentⁱ: Chromosome 17

Subcellular locationⁱ

GO - Cellular componentⁱ

cytosolic large ribosomal subunit Source: GO_Central

Complete GO annotation...

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Initiator methionineⁱ			RemovedBy similarity Manual assertion inferred from sequence similarity toⁱ UniProtKB:Q02878 (RL6_HUMAN)
Chainⁱ	2 – 287	286	60S ribosomal protein L6		PRO_0000171007	Add BLAST

Amino acid modifications

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Modified residueⁱ	126 – 126	1	PhosphoserineBy similarity Manual assertion inferred from sequence similarity toⁱ UniProtKB:Q02878 (RL6_HUMAN)
Modified residueⁱ	238 – 238	1	N6-acetyllysineBy similarity Manual assertion inferred from sequence similarity toⁱ UniProtKB:Q02878 (RL6_HUMAN)

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

PaxDbⁱ	Q58DQ3.
PeptideAtlasⁱ	Q58DQ3.
PRIDEⁱ	Q58DQ3.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSBTAG00000031723.

Bgeeⁱ

ENSBTAG00000031723.

Interactionⁱ

Subunit structureⁱ

May bind IPO9 with low affinity.By similarity

Protein-protein interaction databases

STRINGⁱ	9913.ENSBTAP00000042411.

STRINGⁱ

9913.ENSBTAP00000042411.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q58DQ3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the ribosomal protein L6e family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1694. Eukaryota. COG2163. LUCA.
GeneTreeⁱ	ENSGT00390000003682.
HOGENOMⁱ	HOG000207317.
HOVERGENⁱ	HBG002565.
InParanoidⁱ	Q58DQ3.
KOⁱ	K02934.
OMAⁱ	KYHASRN.
OrthoDBⁱ	EOG091G0L13.
TreeFamⁱ	TF300115.

Family and domain databases

Gene3Dⁱ	2.30.30.30. 1 hit.
InterProⁱ	IPR000915. 60S_ribosomal_L6E. IPR014722. Rib_L2_dom2. IPR005568. Ribosomal_L6_N. IPR008991. Translation_prot_SH3-like. [Graphical view]
PANTHERⁱ	PTHR10715. PTHR10715. 1 hit.
Pfamⁱ	PF01159. Ribosomal_L6e. 1 hit. PF03868. Ribosomal_L6e_N. 1 hit. [Graphical view]
SUPFAMⁱ	SSF50104. SSF50104. 1 hit.
PROSITEⁱ	PS01170. RIBOSOMAL_L6E. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

Q58DQ3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAGEKAEKPD TKEKKPEAKK ADAGKKAKKV EKVKKVKKGK PHCSRNPVLV 
        60         70         80         90        100
RGIGRYSRSA MYSRKALYKR KYSAAKSKVE KKKKVRVLAT VTKPVGGDKN 
       110        120        130        140        150
GGTRVVKLRK MPRYYPTEDV PRKLLSHGKK PFSKHVRKLR ASITPGTILI 
       160        170        180        190        200
ILTGRHRGKR VVFLKQLGSG LLLVTGPLSL NRVPLRRTHQ KFVIATSTKI 
       210        220        230        240        250
DISGVKIPEH LTDTYFKKKK LRKPRHQEGE IFDTEREKYE ITEQRKVDQK 
       260        270        280 
AVDSQILRRI KAVPQLQGYL RSVFALTNGI YPHKVVF

Length:287

Mass (Da):32,690

Last modified:January 23, 2007 - v3

Checksum:ⁱD3546817AB51C143

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BT021543 mRNA. Translation: AAX46390.1. BT021544 mRNA. Translation: AAX46391.1. AY911360 mRNA. Translation: AAW82124.1. BC133430 mRNA. Translation: AAI33431.1.
RefSeqⁱ	NP_001026926.1. NM_001031756.2. XP_005217842.1. XM_005217785.2. XP_005217843.1. XM_005217786.2.
UniGeneⁱ	Bt.62205.

Genome annotation databases

Ensemblⁱ	ENSBTAT00000033359; ENSBTAP00000042411; ENSBTAG00000031723.
GeneIDⁱ	511051.
KEGGⁱ	bta:511051.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BT021543 mRNA. Translation: AAX46390.1. BT021544 mRNA. Translation: AAX46391.1. AY911360 mRNA. Translation: AAW82124.1. BC133430 mRNA. Translation: AAI33431.1.
RefSeqⁱ	NP_001026926.1. NM_001031756.2. XP_005217842.1. XM_005217785.2. XP_005217843.1. XM_005217786.2.
UniGeneⁱ	Bt.62205.

3D structure databases

ProteinModelPortalⁱ	Q58DQ3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9913.ENSBTAP00000042411.

STRINGⁱ

9913.ENSBTAP00000042411.

Proteomic databases

PaxDbⁱ	Q58DQ3.
PeptideAtlasⁱ	Q58DQ3.
PRIDEⁱ	Q58DQ3.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSBTAT00000033359; ENSBTAP00000042411; ENSBTAG00000031723.
GeneIDⁱ	511051.
KEGGⁱ	bta:511051.

Organism-specific databases

CTDⁱ	6128.

CTDⁱ

6128.

Phylogenomic databases

eggNOGⁱ	KOG1694. Eukaryota. COG2163. LUCA.
GeneTreeⁱ	ENSGT00390000003682.
HOGENOMⁱ	HOG000207317.
HOVERGENⁱ	HBG002565.
InParanoidⁱ	Q58DQ3.
KOⁱ	K02934.
OMAⁱ	KYHASRN.
OrthoDBⁱ	EOG091G0L13.
TreeFamⁱ	TF300115.

Enzyme and pathway databases

Reactomeⁱ	R-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression. R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane. R-BTA-6791226. Major pathway of rRNA processing in the nucleolus. R-BTA-72689. Formation of a pool of free 40S subunits. R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit. R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC). R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Reactomeⁱ

R-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Gene expression databases

Bgeeⁱ	ENSBTAG00000031723.

Bgeeⁱ

ENSBTAG00000031723.

Family and domain databases

Gene3Dⁱ	2.30.30.30. 1 hit.
InterProⁱ	IPR000915. 60S_ribosomal_L6E. IPR014722. Rib_L2_dom2. IPR005568. Ribosomal_L6_N. IPR008991. Translation_prot_SH3-like. [Graphical view]
PANTHERⁱ	PTHR10715. PTHR10715. 1 hit.
Pfamⁱ	PF01159. Ribosomal_L6e. 1 hit. PF03868. Ribosomal_L6e_N. 1 hit. [Graphical view]
SUPFAMⁱ	SSF50104. SSF50104. 1 hit.
PROSITEⁱ	PS01170. RIBOSOMAL_L6E. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

RL6_BOVIN

Accessionⁱ

Primary (citable) accession number: Q58DQ3
Secondary accession number(s): A3KMZ3

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	January 23, 2007
Last modified:	September 7, 2016
This is version 79 of the entry and version 3 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Ribosomal proteins
Ribosomal proteins families and list of entries
SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q58DQ3 (RL6_BOVIN)

UniProt

Q58DQ3 - RL6_BOVIN

Your basket is currently empty.

60S ribosomal protein L6

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ