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Protein

Zinc finger protein 205

Gene

ZNF205

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri306 – 328C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri334 – 356C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri362 – 384C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri390 – 412C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri418 – 440C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri446 – 468C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri474 – 496C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri502 – 524C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 205
Gene namesi
Name:ZNF205
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002540221 – 550Zinc finger protein 205Add BLAST550

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki216Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei290PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiQ58DK7
PRIDEiQ58DK7

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000007323

Structurei

3D structure databases

ProteinModelPortaliQ58DK7
SMRiQ58DK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini124 – 193KRABPROSITE-ProRule annotationAdd BLAST70

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri306 – 328C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri334 – 356C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri362 – 384C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri390 – 412C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri418 – 440C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri446 – 468C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri474 – 496C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri502 – 524C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ58DK7
KOiK09228

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 8 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

Sequencei

Sequence statusi: Complete.

Q58DK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADDGGIRA AQDKERARET PGHGHSCQEM LSESEGTVPL GEAWESPHIK
60 70 80 90 100
MEPEEPHPEG VSQETRAEGA RGWVPLSQGT KEKVCFLPGG ALPAPQTPVL
110 120 130 140 150
SREGRTRDRQ MAAALLTAWS QMPVTFEDMA LYLSREEWGR LDHTQQSFYR
160 170 180 190 200
EVLQKRSGLS LGFPFSRPFW ASQVQGKGEA PGSSRQLGHE EEEKRGVVEV
210 220 230 240 250
DKEELAASLG ALGDAKSFKS RMGRAQGEAP RCGQRAASGQ NSGPAKDDVQ
260 270 280 290 300
PCPVKEAQLE SAPPDTDLPK TQEGHFPEQP REGGTAAPES SEEGLALDSE
310 320 330 340 350
AGKKTYKCEQ CGKAFSWHSH LVTHRRTHTG EKPYACTDCG KRFGRSSHLI
360 370 380 390 400
QHQIIHTGEK PYTCPSCWKS FSHHSTLIQH QRIHTGEKPY VCDRCAKRFT
410 420 430 440 450
RRSDLVTHQG THTGAKPHKC PICGKCFTQS SALVTHQRTH TGVKPYPCPE
460 470 480 490 500
CGKCFSQRSN LIAHNRTHTG EKPYHCLDCG KSFSHSSHLT AHQRTHRGVR
510 520 530 540 550
PYSCPLCGKS FSRRSNLHRH EKIHTAGPKA LAMLMLGAAG TLAAPPPAPT
Length:550
Mass (Da):60,459
Last modified:April 26, 2005 - v1
Checksum:iC1B14CA37B485DE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT021590 mRNA Translation: AAX46437.1
BC123477 mRNA Translation: AAI23478.1
RefSeqiNP_001029645.1, NM_001034473.2
UniGeneiBt.6062

Genome annotation databases

GeneIDi514765
KEGGibta:514765

Entry informationi

Entry nameiZN205_BOVIN
AccessioniPrimary (citable) accession number: Q58DK7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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