Reviewed,
UniProtKB/Swiss-Prot Q58929 (MER_METJA)
Last modified
November 3, 2009.
Version 55.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: 5,10-methylenetetrahydromethanopterin reductase EC=1.5.99.11 Alternative name(s): Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase Methylene-H(4)MPT reductase | ||||
| Gene names |
| ||||
| Organism | Methanocaldococcus jannaschii (Methanococcus jannaschii) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 2190 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus |
Protein attributes
| Sequence length | 331 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the reversible reduction of methylene-H4MPT to methyl-H4MPT By similarity. |
| Catalytic activity | 5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_01091 |
| Pathway | One-carbon metabolism; methanogenesis from CO(2); methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 1/2. HAMAP MF_01091 |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the mer family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Methanogenesis One-carbon metabolism |
| Cellular component | Cytoplasm |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | methanogenesis Inferred from electronic annotation. Source: UniProtKB-KW one-carbon metabolic processInferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 331 | 331 | 5,10-methylenetetrahydromethanopterin reductase HAMAP MF_01091 | PRO_0000084807 | |||
Sequences
| ||||||||||||||||||
References
| [1] | "Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii." Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G. Venter J.C.Science 273:1058-1073(1996) [PubMed: 8688087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440. |
Cross-references
Sequence databases | |
|---|---|
| L77117 Genomic DNA. Translation: AAB99555.1. | |
| RefSeq | NP_248542.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1F07 based on UniProtKB Q50744. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1452442. |
| GenomeReviews | Gene locus MJ1534 in contig L77117_GR. |
| KEGG | mja:MJ1534. |
| NMPDR | fig|243232.1.peg.1579. |
| TIGR | MJ1534. |
Phylogenomic databases | |
| HOGENOM | Q58929. |
| OMA | KIPIYMG. |
Enzyme and pathway databases | |
| BioCyc | MJAN243232:MJ_1534-MON. |
| BRENDA | 1.5.99.11. 256362. |
Family and domain databases | |
| HAMAP | MF_01091. [Tree] |
| InterPro | IPR011251. Luciferase-like. IPR016048. Luciferase-like_sub. IPR019946. MeH4methanopterin_reductase. [Graphical view] |
| Gene3D | G3DSA:3.20.20.30. Luciferase_like. 1 hit. |
| Pfam | PF00296. Bac_luciferase. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03555. F420_mer. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MER_METJA | ||||||||
| Accession | Primary (citable) accession number: Q58929 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Methanococcus jannaschii Methanococcus jannaschii: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


