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Q58895 (T2M5_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme MjaV

Short name=R.MjaV
EC=3.1.21.4
Alternative name(s):
Endonuclease MjaV
Type II restriction enzyme MjaV
Gene names
Name:mjaVR
Ordered Locus Names:MJ1500
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recognizes the double-stranded unmethylated sequence GTAC.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionType II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 230230Type-2 restriction enzyme MjaV
PRO_0000077336

Sequences

Sequence LengthMass (Da)Tools
Q58895 [UniParc].

Last modified June 1, 1998. Version 2.
Checksum: 9566FE2061C144D5

FASTA23026,764
        10         20         30         40         50         60 
MDDKSYYEEI ESILRQILQP IEKISFSTFI RVVSGYKIIP IDLSKKEDKE LINDLAKACN 

        70         80         90        100        110        120 
EVIEEIKKTG GVKTKEGKTP KRVNEVGNHI EHYVKDVLNK YGYAITPKTK KGKQKSTGYP 

       130        140        150        160        170        180 
DIEFWYKGKK ERDGRVVYIE IKTFNEKNIN SSHRTFYASP SKDEEGVKIR YDAPHLCLSF 

       190        200        210        220        230 
KIEKLGRDYY ATGFKIIDLS KLKGGIKREF NASNRELYKK DLIIYEKDLK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB99521.1.
PIRC64487.
RefSeqNP_248507.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58895.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ1500.

Protein family/group databases

REBASE3898. MjaV.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB99521; AAB99521; MJ_1500.
GeneID1452407.
KEGGmja:MJ_1500.

Phylogenomic databases

eggNOGNOG281084.
OMAKREFNAS.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameT2M5_METJA
AccessionPrimary (citable) accession number: Q58895
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names