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Q58895

- T2M5_METJA

UniProt

Q58895 - T2M5_METJA

Protein

Type-2 restriction enzyme MjaV

Gene

mjaVR

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 70 (14 May 2014)
      Sequence version 2 (01 Jun 1998)
      Previous versions | rss
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    Functioni

    Recognizes the double-stranded unmethylated sequence GTAC.

    Catalytic activityi

    Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

    GO - Molecular functioni

    1. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    Restriction system

    Protein family/group databases

    REBASEi3898. MjaV.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-2 restriction enzyme MjaV (EC:3.1.21.4)
    Short name:
    R.MjaV
    Alternative name(s):
    Endonuclease MjaV
    Type II restriction enzyme MjaV
    Gene namesi
    Name:mjaVR
    Ordered Locus Names:MJ1500
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 230230Type-2 restriction enzyme MjaVPRO_0000077336Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243232.MJ1500.

    Structurei

    3D structure databases

    ProteinModelPortaliQ58895.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG281084.
    OMAiKREFNAS.

    Sequencei

    Sequence statusi: Complete.

    Q58895-1 [UniParc]FASTAAdd to Basket

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    MDDKSYYEEI ESILRQILQP IEKISFSTFI RVVSGYKIIP IDLSKKEDKE    50
    LINDLAKACN EVIEEIKKTG GVKTKEGKTP KRVNEVGNHI EHYVKDVLNK 100
    YGYAITPKTK KGKQKSTGYP DIEFWYKGKK ERDGRVVYIE IKTFNEKNIN 150
    SSHRTFYASP SKDEEGVKIR YDAPHLCLSF KIEKLGRDYY ATGFKIIDLS 200
    KLKGGIKREF NASNRELYKK DLIIYEKDLK 230
    Length:230
    Mass (Da):26,764
    Last modified:June 1, 1998 - v2
    Checksum:i9566FE2061C144D5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99521.1.
    PIRiC64487.
    RefSeqiNP_248507.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB99521; AAB99521; MJ_1500.
    GeneIDi1452407.
    KEGGimja:MJ_1500.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99521.1 .
    PIRi C64487.
    RefSeqi NP_248507.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q58895.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243232.MJ1500.

    Protein family/group databases

    REBASEi 3898. MjaV.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB99521 ; AAB99521 ; MJ_1500 .
    GeneIDi 1452407.
    KEGGi mja:MJ_1500.

    Phylogenomic databases

    eggNOGi NOG281084.
    OMAi KREFNAS.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
    2. Cited for: CHARACTERIZATION.

    Entry informationi

    Entry nameiT2M5_METJA
    AccessioniPrimary (citable) accession number: Q58895
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: June 1, 1998
    Last modified: May 14, 2014
    This is version 70 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries

    External Data

    Dasty 3