Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q58844 (T2M2_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme MjaII

Short name=R.MjaII
EC=3.1.21.4
Alternative name(s):
Endonuclease MjaII
Type II restriction enzyme MjaII
Gene names
Name:mjaIIR
Ordered Locus Names:MJ1449
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recognizes the double-stranded sequence GGNCC.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

Type II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 370370Type-2 restriction enzyme MjaII
PRO_0000077333

Sequences

Sequence LengthMass (Da)Tools
Q58844 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 8B4CF6208F914B33

FASTA37043,911
        10         20         30         40         50         60 
MPLSKNVIEK ISIETIRVLK SRFDTISDED IKIRNMPFHM AFLRAFYGKI GINDDTEALK 

        70         80         90        100        110        120 
FLTLSQWFHG LSTTLGQSYF ENIAHILSNG EKRTFKNYKI KRSVRDKISE IINDLKSGER 

       130        140        150        160        170        180 
LPNVEKENKE LREATSKNSE YVNGLEFTAD VYFEDKDKVV MIELKTVRPN AGEMRGEKQK 

       190        200        210        220        230        240 
ILYGKAYMME TKPNKKVYYF IGFPYDPTEN PENPCGYDKD RFMSSLIEFS KYFDKREVLI 

       250        260        270        280        290        300 
AEELWSFLSG EENTMKKILD IINSIAKPDF KEKFDFINTF PFINQDRLYT KDAIDEQKFK 

       310        320        330        340        350        360 
KYMDILQEWR LYSEIECAKA VKELSLLKLS SRDRRTFERL INNSMFSNNN KYNENRKMKI 

       370 
LELYNKYMQK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB99461.1.
PIRH64480.
RefSeqNP_248453.1. NC_000909.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ1449.

Protein family/group databases

REBASE1222. MjaII.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB99461; AAB99461; MJ_1449.
GeneID1452353.
KEGGmja:MJ_1449.

Phylogenomic databases

eggNOGNOG136805.
OMAPNAGEMR.
ProtClustDBCLSK2517732.

Family and domain databases

InterProIPR019045. Restrct_endonuc_II_TdeIII.
[Graphical view]
PfamPF09520. RE_TdeIII. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameT2M2_METJA
AccessionPrimary (citable) accession number: Q58844
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names