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Protein

Type-2 restriction enzyme MjaII

Gene

mjaIIR

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Recognizes the double-stranded sequence GGNCC.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processRestriction system

Enzyme and pathway databases

BioCyciMJAN243232:G1GKE-1571-MONOMER

Protein family/group databases

REBASEi1222 MjaII

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme MjaII (EC:3.1.21.4)
Short name:
R.MjaII
Alternative name(s):
Endonuclease MjaII
Type II restriction enzyme MjaII
Gene namesi
Name:mjaIIR
Ordered Locus Names:MJ1449
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000773331 – 370Type-2 restriction enzyme MjaIIAdd BLAST370

Proteomic databases

PRIDEiQ58844

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_1449

Structurei

3D structure databases

SMRiQ58844
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiarCOG07628 Archaea
ENOG410XTRD LUCA
InParanoidiQ58844
OMAiPNAGEMR
OrthoDBiPOG093Z04RE

Family and domain databases

InterProiView protein in InterPro
IPR019045 Restrct_endonuc_II_TdeIII
PfamiView protein in Pfam
PF09520 RE_TdeIII, 1 hit

Sequencei

Sequence statusi: Complete.

Q58844-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLSKNVIEK ISIETIRVLK SRFDTISDED IKIRNMPFHM AFLRAFYGKI
60 70 80 90 100
GINDDTEALK FLTLSQWFHG LSTTLGQSYF ENIAHILSNG EKRTFKNYKI
110 120 130 140 150
KRSVRDKISE IINDLKSGER LPNVEKENKE LREATSKNSE YVNGLEFTAD
160 170 180 190 200
VYFEDKDKVV MIELKTVRPN AGEMRGEKQK ILYGKAYMME TKPNKKVYYF
210 220 230 240 250
IGFPYDPTEN PENPCGYDKD RFMSSLIEFS KYFDKREVLI AEELWSFLSG
260 270 280 290 300
EENTMKKILD IINSIAKPDF KEKFDFINTF PFINQDRLYT KDAIDEQKFK
310 320 330 340 350
KYMDILQEWR LYSEIECAKA VKELSLLKLS SRDRRTFERL INNSMFSNNN
360 370
KYNENRKMKI LELYNKYMQK
Length:370
Mass (Da):43,911
Last modified:November 1, 1996 - v1
Checksum:i8B4CF6208F914B33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB99461.1
PIRiH64480
RefSeqiWP_010870969.1, NC_000909.1

Genome annotation databases

EnsemblBacteriaiAAB99461; AAB99461; MJ_1449
GeneIDi1452353
KEGGimja:MJ_1449

Similar proteinsi

Entry informationi

Entry nameiT2M2_METJA
AccessioniPrimary (citable) accession number: Q58844
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

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