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Q58844

- T2M2_METJA

UniProt

Q58844 - T2M2_METJA

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Protein

Type-2 restriction enzyme MjaII

Gene

mjaIIR

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Recognizes the double-stranded sequence GGNCC.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Restriction system

Protein family/group databases

REBASEi1222. MjaII.

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme MjaII (EC:3.1.21.4)
Short name:
R.MjaII
Alternative name(s):
Endonuclease MjaII
Type II restriction enzyme MjaII
Gene namesi
Name:mjaIIR
Ordered Locus Names:MJ1449
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 370370Type-2 restriction enzyme MjaIIPRO_0000077333Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ1449.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG136805.
InParanoidiQ58844.
OMAiPNAGEMR.

Family and domain databases

InterProiIPR019045. Restrct_endonuc_II_TdeIII.
[Graphical view]
PfamiPF09520. RE_TdeIII. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q58844-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPLSKNVIEK ISIETIRVLK SRFDTISDED IKIRNMPFHM AFLRAFYGKI
60 70 80 90 100
GINDDTEALK FLTLSQWFHG LSTTLGQSYF ENIAHILSNG EKRTFKNYKI
110 120 130 140 150
KRSVRDKISE IINDLKSGER LPNVEKENKE LREATSKNSE YVNGLEFTAD
160 170 180 190 200
VYFEDKDKVV MIELKTVRPN AGEMRGEKQK ILYGKAYMME TKPNKKVYYF
210 220 230 240 250
IGFPYDPTEN PENPCGYDKD RFMSSLIEFS KYFDKREVLI AEELWSFLSG
260 270 280 290 300
EENTMKKILD IINSIAKPDF KEKFDFINTF PFINQDRLYT KDAIDEQKFK
310 320 330 340 350
KYMDILQEWR LYSEIECAKA VKELSLLKLS SRDRRTFERL INNSMFSNNN
360 370
KYNENRKMKI LELYNKYMQK
Length:370
Mass (Da):43,911
Last modified:November 1, 1996 - v1
Checksum:i8B4CF6208F914B33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99461.1.
PIRiH64480.
RefSeqiNP_248453.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB99461; AAB99461; MJ_1449.
GeneIDi1452353.
KEGGimja:MJ_1449.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99461.1 .
PIRi H64480.
RefSeqi NP_248453.1. NC_000909.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ1449.

Protein family/group databases

REBASEi 1222. MjaII.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB99461 ; AAB99461 ; MJ_1449 .
GeneIDi 1452353.
KEGGi mja:MJ_1449.

Phylogenomic databases

eggNOGi NOG136805.
InParanoidi Q58844.
OMAi PNAGEMR.

Family and domain databases

InterProi IPR019045. Restrct_endonuc_II_TdeIII.
[Graphical view ]
Pfami PF09520. RE_TdeIII. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiT2M2_METJA
AccessioniPrimary (citable) accession number: Q58844
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

External Data

Dasty 3