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Q58723 (T2M4_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme MjaIV

Short name=R.MjaIV
EC=3.1.21.4
Alternative name(s):
Endonuclease MjaIV
Type II restriction enzyme MjaIV
Gene names
Name:mjaIVR
Ordered Locus Names:MJ1327
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recognizes the double-stranded unmethylated sequence GTNNAC.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
   Biological processRestriction system
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionType II site-specific deoxyribonuclease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245Type-2 restriction enzyme MjaIV
PRO_0000077335

Sequences

Sequence LengthMass (Da)Tools
Q58723 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4597C2B8EF1FA973

FASTA24528,779
        10         20         30         40         50         60 
MVVKLVNNEL KILSGKLRDI FREIYNKIKN DENINDRNLD DKVLSLLKDY TISEENLKIK 

        70         80         90        100        110        120 
FSEPKDEIYS YEGRRTPYDL LCYGIINGKN FLIFINNKFG DLKSNTRNDV TTYNNLLRLY 

       130        140        150        160        170        180 
LGIKRQRLTS EITINGELVY NRISGNEIVS YGIFVVDKYR RGYKFFLLEE IKDDFYVNPR 

       190        200        210        220        230        240 
NNMFQIRYSP NLGDPIDYFA FVKKLIDAIL ESLEKSLNSI KTEILVLNSI KIQLINIKEG 


KHGED 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB99343.1.
PIRF64465.
RefSeqNP_248327.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58723.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ1327.

Protein family/group databases

REBASE3894. MjaIV.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB99343; AAB99343; MJ_1327.
GeneID1452229.
KEGGmja:MJ_1327.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameT2M4_METJA
AccessionPrimary (citable) accession number: Q58723
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names