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Protein

Type-2 restriction enzyme MjaIV

Gene

mjaIVR

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Recognizes the double-stranded unmethylated sequence GTNNAC.

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

GO - Molecular functioni

  1. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Restriction system

Enzyme and pathway databases

BRENDAi3.1.21.4. 3260.

Protein family/group databases

REBASEi3894. MjaIV.

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzyme MjaIV (EC:3.1.21.4)
Short name:
R.MjaIV
Alternative name(s):
Endonuclease MjaIV
Type II restriction enzyme MjaIV
Gene namesi
Name:mjaIVR
Ordered Locus Names:MJ1327
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 245245Type-2 restriction enzyme MjaIVPRO_0000077335Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ1327.

Structurei

3D structure databases

ProteinModelPortaliQ58723.
ModBaseiSearch...
MobiDBiSearch...

Sequencei

Sequence statusi: Complete.

Q58723-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVKLVNNEL KILSGKLRDI FREIYNKIKN DENINDRNLD DKVLSLLKDY
60 70 80 90 100
TISEENLKIK FSEPKDEIYS YEGRRTPYDL LCYGIINGKN FLIFINNKFG
110 120 130 140 150
DLKSNTRNDV TTYNNLLRLY LGIKRQRLTS EITINGELVY NRISGNEIVS
160 170 180 190 200
YGIFVVDKYR RGYKFFLLEE IKDDFYVNPR NNMFQIRYSP NLGDPIDYFA
210 220 230 240
FVKKLIDAIL ESLEKSLNSI KTEILVLNSI KIQLINIKEG KHGED
Length:245
Mass (Da):28,779
Last modified:October 31, 1996 - v1
Checksum:i4597C2B8EF1FA973
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99343.1.
PIRiF64465.
RefSeqiNP_248327.1. NC_000909.1.
WP_010870844.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB99343; AAB99343; MJ_1327.
GeneIDi1452229.
KEGGimja:MJ_1327.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99343.1.
PIRiF64465.
RefSeqiNP_248327.1. NC_000909.1.
WP_010870844.1. NC_000909.1.

3D structure databases

ProteinModelPortaliQ58723.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243232.MJ1327.

Protein family/group databases

REBASEi3894. MjaIV.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB99343; AAB99343; MJ_1327.
GeneIDi1452229.
KEGGimja:MJ_1327.

Enzyme and pathway databases

BRENDAi3.1.21.4. 3260.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiT2M4_METJA
AccessioniPrimary (citable) accession number: Q58723
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2000
Last sequence update: October 31, 1996
Last modified: March 31, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.