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Protein

Uncharacterized adenine-specific methylase MJ1220

Gene

MJ1220

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei303S-adenosyl-L-methionineBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMJAN243232:G1GKE-1324-MONOMER

Protein family/group databases

REBASEi3905 M.MjaORF1220P

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized adenine-specific methylase MJ1220 (EC:2.1.1.72)
Gene namesi
Ordered Locus Names:MJ1220
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000880011 – 578Uncharacterized adenine-specific methylase MJ1220Add BLAST578

Proteomic databases

PRIDEiQ58617

Interactioni

Protein-protein interaction databases

STRINGi243232.MJ_1220

Structurei

3D structure databases

ProteinModelPortaliQ58617
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni280 – 282S-adenosyl-L-methionine bindingBy similarity3

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.Curated

Phylogenomic databases

eggNOGiarCOG02632 Archaea
COG0286 LUCA
InParanoidiQ58617
KOiK03427
OMAiNVSKGYF
OrthoDBiPOG093Z01PP
PhylomeDBiQ58617

Family and domain databases

Gene3Di1.20.1260.30, 1 hit
InterProiView protein in InterPro
IPR022749 D12N6_MeTrfase_N
IPR038333 D12N6_MeTrfase_N_sf
IPR003356 DNA_methylase_A-5
IPR002052 DNA_methylase_N6_adenine_CS
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF12161 HsdM_N, 1 hit
PF02384 N6_Mtase, 1 hit
SUPFAMiSSF53335 SSF53335, 2 hits
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q58617-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLRNVEPRF LKAYNILMDK FGLFPFTYDM AEKVLKDNYE NVNEVLSKLA
60 70 80 90 100
DAGLLEKTAK KEDKRKKIYK IKPLTTEKIE KVSKDKLIGL LKQGADLIRT
110 120 130 140 150
QVDYKVLLLF LFFKAISDKY LLKVEELKKE FEDLDEEDIY VLANEEILEL
160 170 180 190 200
YDVEGKKLYV WHEVANNPED FINALNKIVE MNKEKLSGLD ELIKRTGLPT
210 220 230 240 250
LFENENRHIV QHLINLFSRA DFSEASYDIL GDAYEWTLNY FAPTKAKEGE
260 270 280 290 300
VYTPIEVSKL IAHLVEPKDD EVILDPACGS GSMLIEQYRF AGSNPNIVLV
310 320 330 340 350
GQERNDVTAV LAKLNFILHG INLKDAKVFI GDSLLNPKFE SFIXEVKGTG
360 370 380 390 400
KADKVVANPP WNQDGYDENT LKVNEKYKDI YMYGFPNKNS ADWAWVQLIN
410 420 430 440 450
YYTEKKAGIV LDSGALFRGG KEKTIRKRFV DDDLIEAVVL LPEKLFYNCP
460 470 480 490 500
APGIILILNK NKPEERKGKI LFINASNEYI KHPEVKKLNK LSDENIEKIA
510 520 530 540 550
KAYKEFKDVD GFCKVVDIEE IRKNDYNLNV SLYISPIEED EDVDLGEVYE
560 570
ELNKLHNEYL EKFEVVKGYL EEINGLIK
Length:578
Mass (Da):66,638
Last modified:November 1, 1997 - v1
Checksum:i5339ED873EF8E9E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA Translation: AAB99225.1
PIRiC64452
RefSeqiWP_010870732.1, NC_000909.1

Genome annotation databases

EnsemblBacteriaiAAB99225; AAB99225; MJ_1220
GeneIDi1452116
KEGGimja:MJ_1220

Similar proteinsi

Entry informationi

Entry nameiY1220_METJA
AccessioniPrimary (citable) accession number: Q58617
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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