Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q58606

- MTM6_METJA

UniProt

Q58606 - MTM6_METJA

Protein

Modification methylase MjaVI

Gene

mjaVIM

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 2 (01 Jun 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    This methylase recognizes the double-stranded sequence CCGG, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the MjaVI endonuclease.Curated

    Catalytic activityi

    S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine.

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. N-methyltransferase activity Source: InterPro
    3. site-specific DNA-methyltransferase (cytosine-N4-specific) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    Restriction system

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Protein family/group databases

    REBASEi3893. M.MjaVI.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Modification methylase MjaVI (EC:2.1.1.113)
    Short name:
    M.MjaVI
    Alternative name(s):
    N-4 cytosine-specific methyltransferase MjaVI
    Gene namesi
    Name:mjaVIM
    Ordered Locus Names:MJ1209
    OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
    Taxonomic identifieri243232 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
    ProteomesiUP000000805: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194Modification methylase MjaVIPRO_0000087939Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ58606.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0863.
    OMAiSFMSASA.
    PhylomeDBiQ58606.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    InterProiIPR002941. DNA_methylase_N4/N6.
    IPR017985. MeTrfase_CN4_CS.
    IPR001091. RM_Methylase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF01555. N6_N4_Mtase. 1 hit.
    [Graphical view]
    PRINTSiPR00508. S21N4MTFRASE.
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS00093. N4_MTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q58606-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVIIVKIWN KINGITLIND DFLNVDLPNE SIDLIVTSPP YNVGIDYNQH    50
    DDTIPYEEYL DWTKQWLKKA LTLLKKDGRL CLNIPLDKNK GGIKPVYADI 100
    VKIALDVGFK YQTTIIWNEQ NISRRTAWGS FMSASAPYVI APVETIVVLY 150
    KESWKKLSKG ESDITKEEFI EWTNGLWTFP GESKKELDIQ HHFR 194
    Length:194
    Mass (Da):22,461
    Last modified:June 1, 1998 - v2
    Checksum:i6DB2BAEEAEAEBC10
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99220.1.
    RefSeqiWP_010870962.1. NC_000909.1.
    YP_003727984.1. NC_000909.1.

    Genome annotation databases

    EnsemblBacteriaiAAB99220; AAB99220; MJ_1209.
    GeneIDi9348047.
    KEGGimja:MJ_1209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L77117 Genomic DNA. Translation: AAB99220.1 .
    RefSeqi WP_010870962.1. NC_000909.1.
    YP_003727984.1. NC_000909.1.

    3D structure databases

    ProteinModelPortali Q58606.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 3893. M.MjaVI.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB99220 ; AAB99220 ; MJ_1209 .
    GeneIDi 9348047.
    KEGGi mja:MJ_1209.

    Phylogenomic databases

    eggNOGi COG0863.
    OMAi SFMSASA.
    PhylomeDBi Q58606.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    InterProi IPR002941. DNA_methylase_N4/N6.
    IPR017985. MeTrfase_CN4_CS.
    IPR001091. RM_Methylase.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF01555. N6_N4_Mtase. 1 hit.
    [Graphical view ]
    PRINTSi PR00508. S21N4MTFRASE.
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS00093. N4_MTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.

    Entry informationi

    Entry nameiMTM6_METJA
    AccessioniPrimary (citable) accession number: Q58606
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 77 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Methanococcus jannaschii
      Methanococcus jannaschii: entries and gene names
    2. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3