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Q58606 (MTM6_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Modification methylase MjaVI

Short name=M.MjaVI
EC=2.1.1.113
Alternative name(s):
N-4 cytosine-specific methyltransferase MjaVI
Gene names
Name:mjaVIM
Ordered Locus Names:MJ1209
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This methylase recognizes the double-stranded sequence CCGG, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the MjaVI endonuclease Potential.

Catalytic activity

S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine.

Sequence similarities

Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 194194Modification methylase MjaVI
PRO_0000087939

Sequences

Sequence LengthMass (Da)Tools
Q58606 [UniParc].

Last modified June 1, 1998. Version 2.
Checksum: 6DB2BAEEAEAEBC10

FASTA19422,461
        10         20         30         40         50         60 
MKVIIVKIWN KINGITLIND DFLNVDLPNE SIDLIVTSPP YNVGIDYNQH DDTIPYEEYL 

        70         80         90        100        110        120 
DWTKQWLKKA LTLLKKDGRL CLNIPLDKNK GGIKPVYADI VKIALDVGFK YQTTIIWNEQ 

       130        140        150        160        170        180 
NISRRTAWGS FMSASAPYVI APVETIVVLY KESWKKLSKG ESDITKEEFI EWTNGLWTFP 

       190 
GESKKELDIQ HHFR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB99220.1.
RefSeqYP_003727984.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58606.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

REBASE3893. M.MjaVI.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB99220; AAB99220; MJ_1209.
GeneID9348047.
KEGGmja:MJ_1209.

Phylogenomic databases

eggNOGCOG0863.
OMASFMSASA.
PhylomeDBQ58606.

Family and domain databases

Gene3D3.40.50.150. 1 hit.
InterProIPR002941. DNA_methylase_N4/N6.
IPR017985. MeTrfase_CN4_CS.
IPR001091. RM_Methylase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamPF01555. N6_N4_Mtase. 1 hit.
[Graphical view]
PRINTSPR00508. S21N4MTFRASE.
SUPFAMSSF53335. SSF53335. 1 hit.
PROSITEPS00093. N4_MTASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTM6_METJA
AccessionPrimary (citable) accession number: Q58606
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: July 9, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names