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Q58600 (MT52_METJA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable modification methylase MJ1200

EC=2.1.1.37
Alternative name(s):
Cytosine-specific methyltransferase MJ1200
M.MjaVIIP
Gene names
Ordered Locus Names:MJ1200
OrganismMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) [Reference proteome] [HAMAP]
Taxonomic identifier243232 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

Contains 1 SAM-dependent MTase C5-type domain.

Ontologies

Keywords
   Biological processRestriction system
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA restriction-modification system

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA (cytosine-5-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366Probable modification methylase MJ1200
PRO_0000087917

Regions

Domain5 – 366362SAM-dependent MTase C5-type

Sites

Active site1331 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q58600 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 9D5C60CA603FBCFE

FASTA36642,269
        10         20         30         40         50         60 
MVIMLKFIDL FCGCGGFSRG FVEEGFEPLV AIELNEDAAF SYALNFNGQI YEKIRPGEFK 

        70         80         90        100        110        120 
LKELKGYVGI YPFKFPFEEE DIKWLKRLGT LNEKTKKLSP VVINDDIREI HAIEIEKFIK 

       130        140        150        160        170        180 
NKKVDVIIGG PPCEGYTGAN PKREKNPYDR LYKDETGRLV LEYIRIVGDL QPKIFVMENV 

       190        200        210        220        230        240 
PGIKEVRGAI IKEFREIGYE DVYFNTLRAE DYGNPSVRRR VFVSNIEINP EKTQPKTVIE 

       250        260        270        280        290        300 
AIGDLMYKGR DVPNHEFAAL PARFRKRVHK LGWGDAFIYF KGANRRLGNY IRLHPLKLAE 

       310        320        330        340        350        360 
TVMGKRFFIH PYEDRLLTPR EQARLMSYPD YHLFAGGIRS CYNQIGESVP VALSRAIARV 


IKENLK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L77117 Genomic DNA. Translation: AAB99203.1.
PIRG64449.
RefSeqNP_248195.1. NC_000909.1.

3D structure databases

ProteinModelPortalQ58600.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243232.MJ1200.

Protein family/group databases

REBASE3906. M.MjaORF1200P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB99203; AAB99203; MJ_1200.
GeneID1452095.
KEGGmja:MJ_1200.

Phylogenomic databases

eggNOGCOG0270.
KOK00558.
OMARDVPNHE.
PhylomeDBQ58600.

Family and domain databases

Gene3D3.40.50.150. 2 hits.
InterProIPR001525. C5_MeTfrase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PANTHERPTHR10629. PTHR10629. 1 hit.
PfamPF00145. DNA_methylase. 2 hits.
[Graphical view]
PRINTSPR00105. C5METTRFRASE.
SUPFAMSSF53335. SSF53335. 2 hits.
PROSITEPS51679. SAM_MT_C5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMT52_METJA
AccessionPrimary (citable) accession number: Q58600
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Methanococcus jannaschii

Methanococcus jannaschii: entries and gene names