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Protein

Putative arsenical pump-driving ATPase

Gene

MJ1142

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity).By similarity

Catalytic activityi

ATP + H2O + arsenite(In) = ADP + phosphate + arsenite(Out).

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 408ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Arsenical resistance

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative arsenical pump-driving ATPase (EC:3.6.3.16)
Alternative name(s):
Arsenical resistance ATPase
Arsenite-translocating ATPase
Arsenite-transporting ATPase
Gene namesi
Ordered Locus Names:MJ1142
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 349349Putative arsenical pump-driving ATPasePRO_0000152257Add
BLAST

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-7584233,EBI-7584233

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

IntActiQ58542. 5 interactions.
MINTiMINT-8378538.
STRINGi243232.MJ_1142.

Structurei

Secondary structure

1
349
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi13 – 219Combined sources
Beta strandi27 – 326Combined sources
Beta strandi34 – 363Combined sources
Helixi39 – 5214Combined sources
Beta strandi57 – 615Combined sources
Helixi67 – 726Combined sources
Beta strandi77 – 793Combined sources
Beta strandi87 – 937Combined sources
Helixi96 – 11015Combined sources
Helixi111 – 1133Combined sources
Helixi115 – 13016Combined sources
Helixi134 – 14815Combined sources
Beta strandi153 – 1575Combined sources
Helixi165 – 1706Combined sources
Helixi171 – 19929Combined sources
Helixi211 – 23222Combined sources
Turni235 – 2373Combined sources
Beta strandi238 – 2447Combined sources
Helixi248 – 26316Combined sources
Beta strandi268 – 2769Combined sources
Helixi284 – 30320Combined sources
Beta strandi307 – 3137Combined sources
Helixi322 – 33211Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UG6X-ray3.30A/B/C/D1-349[»]
3UG7X-ray2.90A/B/C/D1-349[»]
ProteinModelPortaliQ58542.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arsA ATPase family.Curated

Phylogenomic databases

eggNOGiarCOG02849. Archaea.
COG0003. LUCA.
InParanoidiQ58542.
KOiK01551.
OMAiYEIDTHN.
PhylomeDBiQ58542.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR025723. Anion-transp_ATPase-like_dom.
IPR016300. ATPase_ArsA/GET3.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10803. PTHR10803. 1 hit.
PfamiPF02374. ArsA_ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00345. GET3_arsA_TRC40. 1 hit.

Sequencei

Sequence statusi: Complete.

Q58542-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSKIKDSIN SLRGITEKKL EKKDGTKYIM FGGKGGVGKT TMSAATGVYL
60 70 80 90 100
AEKGLKVVIV STDPAHSLRD IFEQEFGHEP TKVKGYDNLY VVEIDPQKAM
110 120 130 140 150
EEYKEKLKAQ IEENPFLGEM LEDQLEMAAL SPGTDESAAF DVFLKYMDSN
160 170 180 190 200
EFDVVIFDTA PTGHTLRFLG MPEVMDKYMT KLIKLRKQMS GFMKMMKKLL
210 220 230 240 250
PFGGKDEDID YDKMLEELEK MKERIVRARN ILSDPERTAF RLVVIPEEMS
260 270 280 290 300
ILESERAMKA LQKYGIPIDA VIVNQLIPED VQCDFCRARR ELQLKRLEMI
310 320 330 340
KEKFGDKVIA YVPLLRTEAK GIETLKQIAK ILYGEEEKEE QKIEQKVGQ
Length:349
Mass (Da):39,919
Last modified:November 1, 1996 - v1
Checksum:i00041F603DFDD5A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99142.1.
PIRiE64442.

Genome annotation databases

EnsemblBacteriaiAAB99142; AAB99142; MJ_1142.
KEGGimja:MJ_1142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB99142.1.
PIRiE64442.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UG6X-ray3.30A/B/C/D1-349[»]
3UG7X-ray2.90A/B/C/D1-349[»]
ProteinModelPortaliQ58542.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ58542. 5 interactions.
MINTiMINT-8378538.
STRINGi243232.MJ_1142.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB99142; AAB99142; MJ_1142.
KEGGimja:MJ_1142.

Phylogenomic databases

eggNOGiarCOG02849. Archaea.
COG0003. LUCA.
InParanoidiQ58542.
KOiK01551.
OMAiYEIDTHN.
PhylomeDBiQ58542.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR025723. Anion-transp_ATPase-like_dom.
IPR016300. ATPase_ArsA/GET3.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10803. PTHR10803. 1 hit.
PfamiPF02374. ArsA_ATPase. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00345. GET3_arsA_TRC40. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiARSA_METJA
AccessioniPrimary (citable) accession number: Q58542
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: November 11, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.