MJ1142

Functionⁱ

Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity).By similarity

Catalytic activityⁱ

ATP + H₂O + arsenite(In) = ADP + phosphate + arsenite(Out).

Regions

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Nucleotide bindingⁱ	33 – 40	8	ATPSequence analysis

GO - Molecular functionⁱ

arsenite-transmembrane transporting ATPase activity Source: UniProtKB-EC
ATP binding Source: UniProtKB-KW
identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 22124326

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Putative arsenical pump-driving ATPase (EC:3.6.3.16) Alternative name(s): Arsenical resistance ATPase Arsenite-translocating ATPase Arsenite-transporting ATPase
Gene namesⁱ	Ordered Locus Names:MJ1142
Organismⁱ	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifierⁱ	243232 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanocaldococcaceae › Methanocaldococcus › Methanocaldococcus jannaschii
Proteomesⁱ	UP000000805 Componentⁱ: Chromosome

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Chainⁱ	1 – 349	349	Putative arsenical pump-driving ATPase		PRO_0000152257	Add BLAST

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
itself		3	EBI-7584233,EBI-7584233

With

Entry

#Exp.

IntAct

Notes

itself

3

EBI-7584233,EBI-7584233

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 22124326

Protein-protein interaction databases

IntActⁱ	Q58542. 5 interactions.
MINTⁱ	MINT-8378538.
STRINGⁱ	243232.MJ_1142.

Structureⁱ

Secondary structure

1

349

Legend: HelixTurnBeta strand

Show more details

Feature key	Position(s)	Length	Description
Helixⁱ	13 – 21	9	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	27 – 32	6	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	34 – 36	3	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	39 – 52	14	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	57 – 61	5	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	67 – 72	6	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	77 – 79	3	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG6
Beta strandⁱ	87 – 93	7	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	96 – 110	15	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	111 – 113	3	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	115 – 130	16	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	134 – 148	15	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	153 – 157	5	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	165 – 170	6	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	171 – 199	29	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	211 – 232	22	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Turnⁱ	235 – 237	3	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	238 – 244	7	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	248 – 263	16	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	268 – 276	9	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	284 – 303	20	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Beta strandⁱ	307 – 313	7	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7
Helixⁱ	322 – 332	11	Combined sources Manual assertion inferred from combination of experimental and computational evidenceⁱ PDB:3UG7

3D structure databases

Select the link destinations:
PDBeⁱ
RCSB PDBⁱ
PDBjⁱ

Links Updated

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3UG6	X-ray	3.30	A/B/C/D	1-349	[»]
3UG7	X-ray	2.90	A/B/C/D	1-349	[»]

ProteinModelPortalⁱ

Q58542.

ModBaseⁱ

Search...

MobiDBⁱ

Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the arsA ATPase family.Curated

Phylogenomic databases

eggNOGⁱ	arCOG02849. Archaea. COG0003. LUCA.
InParanoidⁱ	Q58542.
KOⁱ	K01551.
OMAⁱ	YEIDTHN.
PhylomeDBⁱ	Q58542.

Family and domain databases

Gene3Dⁱ	3.40.50.300. 2 hits.
InterProⁱ	IPR025723. Anion-transp_ATPase-like_dom. IPR016300. ATPase_ArsA/GET3. IPR027417. P-loop_NTPase. [Graphical view]
PANTHERⁱ	PTHR10803. PTHR10803. 1 hit.
Pfamⁱ	PF02374. ArsA_ATPase. 1 hit. [Graphical view]
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00345. GET3_arsA_TRC40. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q58542-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLSKIKDSIN SLRGITEKKL EKKDGTKYIM FGGKGGVGKT TMSAATGVYL 
        60         70         80         90        100
AEKGLKVVIV STDPAHSLRD IFEQEFGHEP TKVKGYDNLY VVEIDPQKAM 
       110        120        130        140        150
EEYKEKLKAQ IEENPFLGEM LEDQLEMAAL SPGTDESAAF DVFLKYMDSN 
       160        170        180        190        200
EFDVVIFDTA PTGHTLRFLG MPEVMDKYMT KLIKLRKQMS GFMKMMKKLL 
       210        220        230        240        250
PFGGKDEDID YDKMLEELEK MKERIVRARN ILSDPERTAF RLVVIPEEMS 
       260        270        280        290        300
ILESERAMKA LQKYGIPIDA VIVNQLIPED VQCDFCRARR ELQLKRLEMI 
       310        320        330        340 
KEKFGDKVIA YVPLLRTEAK GIETLKQIAK ILYGEEEKEE QKIEQKVGQ

Length:349

Mass (Da):39,919

Last modified:November 1, 1996 - v1

Checksum:ⁱ00041F603DFDD5A3

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L77117 Genomic DNA. Translation: AAB99142.1.
PIRⁱ	E64442.

Genome annotation databases

EnsemblBacteriaⁱ	AAB99142; AAB99142; MJ_1142.
KEGGⁱ	mja:MJ_1142.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L77117 Genomic DNA. Translation: AAB99142.1.
PIRⁱ	E64442.

3D structure databases

Select the link destinations:
PDBeⁱ
RCSB PDBⁱ
PDBjⁱ

Links Updated

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3UG6	X-ray	3.30	A/B/C/D	1-349	[»]
3UG7	X-ray	2.90	A/B/C/D	1-349	[»]

ProteinModelPortalⁱ

Q58542.

ModBaseⁱ

Search...

MobiDBⁱ

Search...

Protein-protein interaction databases

IntActⁱ	Q58542. 5 interactions.
MINTⁱ	MINT-8378538.
STRINGⁱ	243232.MJ_1142.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAB99142; AAB99142; MJ_1142.
KEGGⁱ	mja:MJ_1142.

Phylogenomic databases

eggNOGⁱ	arCOG02849. Archaea. COG0003. LUCA.
InParanoidⁱ	Q58542.
KOⁱ	K01551.
OMAⁱ	YEIDTHN.
PhylomeDBⁱ	Q58542.

Family and domain databases

Gene3Dⁱ	3.40.50.300. 2 hits.
InterProⁱ	IPR025723. Anion-transp_ATPase-like_dom. IPR016300. ATPase_ArsA/GET3. IPR027417. P-loop_NTPase. [Graphical view]
PANTHERⁱ	PTHR10803. PTHR10803. 1 hit.
Pfamⁱ	PF02374. ArsA_ATPase. 1 hit. [Graphical view]
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00345. GET3_arsA_TRC40. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

ARSA_METJA

Accessionⁱ

Primary (citable) accession number: Q58542

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	November 11, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

Methanococcus jannaschii
Methanococcus jannaschii: entries and gene names
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q58542 (ARSA_METJA)

UniProt

Q58542 - ARSA_METJA

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Putative arsenical pump-driving ATPase

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ